Journals / Akademik Gastroenteroloji Dergisi / 2011 / Cilt: 10 - Sayı: 2

The frequency of cholelithiasis in patients with cirrhosis due to chronic hepatitis B and chronic hepatitis C

Kronik hepatit B ve kronik hepatit C’ ye bağlı gelişen sirozlu hastalarda safra kesesi taşlı sıklığı

Pages
56–60
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It would be useful to observe the patients with cirrhosis for early diagnosis and treatment of cholelithiasis.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Aims: Many studies have shown that the prevalence of cholelithiasis in cirrhosis is increased 2-5 times compared to the normal population.
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Key Findings & Data:Materials and Methods: A total of 305 patients between the ages of 18-70 years with cirrhosis due to chronic hepatitis B and chronic hepatitis C were enrolled in the study.
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Conclusion & Impact:It would be useful to observe the patients with cirrhosis for early diagnosis and treatment of cholelithiasis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background and Aims: Many studies have shown that the prevalence of cholelithiasis in cirrhosis is increased 2-5 times compared to the normal population. In this study, patients followed with liver cirrhosis due to chronic hepatitis B and chronic hepatitis C were investigated regarding the prevalence of cholelithiasis (gallstones) and the relation of this with age, gender and etiology of the disease. Materials and Methods: A total of 305 patients between the ages of 18-70 years with cirrhosis due to chronic hepatitis B and chronic hepatitis C were enrolled in the study. Patients with chronic hepatitis B and chronic hepatitis C and the patients with cirrhosis were compared with regard to age, gender and the frequency of cholelithiasis. Results: There were 67 patients (33 female, 44 male) with cirrhosis, and the mean age was 54±13 years. Cholelithiasis was determined in 12 of 67 patients with cirrhosis, and when they were examined in terms of gender, there was no significant difference between female (4, 33.3%) and male (8, 66.7%) patients. No statistically significant difference was found regarding the presence of cholelithiasis between the patients with cirrhosis due to hepatitis B or hepatitis C. However, the frequency of cholelithiasis was greater in patients with hepatitis B. Conclusions: The incidence of cholelithiasis in patients with cirrhosis is 17.9%. This is similar to the rates that have been reported previously about the frequency of cholelithiasis (7-30%). It would be useful to observe the patients with cirrhosis for early diagnosis and treatment of cholelithiasis.

Özet

Giriş ve Amaç: Birçok çalışmada, sirozda safra kesesi taşı prevalansı nın normal popülasyona göre arttığı bildirilmiştir. Bu çalışmada kronik hepatit B ve kronik hepatit C’ye bağlı gelişen karaciğer sirozu nedeniyle takipli hastalardaki safra kesesi taşı sıklığı ve bunun yaş, cinsiyet, hastalık etiyolojisi ile ilişkisinin araştırılması planlanmıştır. Gereç ve Yöntem: Çalışmamızda 2005–2010 yılları arasında Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Gastroenteroloji kliniğine başvuran, 18–70 yaş aralığındaki kronik hepatit B, kronik hepatit C ve bunlara bağlı siroz gelişmiş olan toplam 305 hasta incelendi. Kronik hepatit B ve kronik hepatit C hastaları, bunlara bağlı siroz gelişmiş hastalar yaş, cinsiyet, safra kesesi taşı sıklığı açısından karşılaştırıldı. Bulgular: Siroz tanısı olan hasta sayısı 67 (33 kadın, 44 erkek) olup yaş ortalaması 54±13 idi. Sirozlu 67 olgunun 12’sinde safra kesesi taşı tespit edilmiş olup, bu 12 hastada kadın (4,%33,3) ve erkek (8, %66,7) cinsiyet açı sından istatistiksel olarak anlamlı fark bulunmamıştır. HBV’ye bağlı sirozlu olgularla, HCV’ye bağlı sirozlu olgular arasında safra kesesi taşı varlığı açısından istatiksel bir fark saptanmadı. Ancak HBV’li olgularda safra kesesi taşı sıklığı daha sık izlenmiştir. Sonuç: Hastalarımızda sirozlu olgularda safra kesesi taşı görülme sıklığı %17,9 olarak saptanmı ştır. Bu oran daha önce ülkemizden bildirilen safra kesesi taşı sıklığı oranlarıyla (%7-30) benzerdir. Sirozlu olguların safra kesesi taşı açısından erken tanı ve takibi yararlı olacaktır.

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Cite This Article

YILDIZ, P., ŞENATEŞ, E., YEŞİL, A., BAYOĞLU, İ. V., YEŞİL, E. E., DEMİRTUNÇ, R. (2011). The frequency of cholelithiasis in patients with cirrhosis due to chronic hepatitis B and chronic hepatitis C. Akademik Gastroenteroloji Dergisi, Cilt: 10 - Sayı: 2, 56–60. https://ajindex.com/articles/161234

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