Journals / Çocuk Enfeksiyon Dergisi / 2017 / Cilt: 11 - Sayı: 4

A Retrospective Analysis of Rotavirus and Adenovirus Infections in Pediatric Population Admitted to Emergency Department with Acute Gastroenteritis

Akut Gastroenteritle Acile Başvuran Pediatrik Popülasyonda Rotavirüs ve Adenovirüs Enfeksiyonlarının Retrospektif Analizi

Pages
153–160
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Describing the characteristics of the infections may help to eliminate unnecessary tests and inappropriate diagnoses especially in emergency settings.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Acute gastroenteritis (AGE) is a frequent reason of morbidity and mortality in children in both developed and underdeveloped countries.
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Key Findings & Data:We aimed to review the frequency, and the age, gender, season of admission, characteristics and rate of hospitalization of rotavirus and adenovirus infections in pediatric population admitted to emergency department with AGE in which stool analysis was performed.
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Conclusion & Impact:Describing the characteristics of the infections may help to eliminate unnecessary tests and inappropriate diagnoses especially in emergency settings.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Acute gastroenteritis (AGE) is a frequent reason of morbidity and mortality in children in both developed and underdeveloped countries. It is mostly caused by infectious agents which differ according to age groups and seasons. We aimed to review the frequency, and the age, gender, season of admission, characteristics and rate of hospitalization of rotavirus and adenovirus infections in pediatric population admitted to emergency department with AGE in which stool analysis was performed. Material and Methods: The records of 5526 patients aged between 0-16 years who were admitted to pediatric emergency unit with AGE in a year and in which stool analysis were performed were reviewed. Frequency of rotavirus and adenovirus cases, gender and age distribution and hospitalization data were analyzed. Results: A total of 5526 patients with AGE, 2303 females and 3223 males, with a mean age of 5.21 ± 3.40 were included. Adenovirus was detected in 3.1% and rotavirus was detected in 22.4% of all cases. There were no significant differences between genders in adenovirus and rotavirus cases. Rotavirus infection was significantly high in children aged between 7 months-2 years and 3-6 years while adenovirus infection rate was similar in all age groups except adolescence. Rotavirus detection was significantly higher in winter months whereas adenovirus infections are seen throughout the year. Among rotavirus cases (n= 1240); 344 (27.7%) patients were taken under observation and 73 (5.9%) patients were hospitalized. For adenovirus cases (n= 169); 50 (29.6%) patients were taken under observation and 10 (5.9%) patients were hospitalized. Conclusion: Our study consists of a remarkable number of patients. Rotavirus has a seasonal pattern and is more frequent in younger children and requires more hospitalization. Describing the characteristics of the infections may help to eliminate unnecessary tests and inappropriate diagnoses especially in emergency settings.

Özet

Giriş: Akut ishaller, gelişmiş ve gelişmekte olan ülkelerde çocuklarda morbidite ve mortalitenin sık görülen nedenlerindendir. Çoğunlukla yaş gruplarına ve mevsimlere göre farklılıklar gösteren enfeksiyöz ajanlar tarafından oluşturulur. Biz bu çalışmada Çocuk Acil Polikliniğimize akut gastroenterit nedeniyle gelen ve gaita tahlili yapılan pediatrik hasta gru-bunda rotavirüs ve adenovirüs sıklığını, bu enfeksiyonlar için mevsim, cinsiyet, yaş özelliklerini ve gözleme alınma, hastaneye yatış üzerine et-kilerini araştırmayı amaçladık. Gereç ve Yöntemler: Çalışmamıza 0-16 yaş grubunda, akut gastroente-rit şikayeti ile bir yılda Çocuk Acil’e başvuran ve gaita tahlili yapılmış olan 5526 hasta alındı. Tüm olgularda rotavirüs varlığı, adenovirüs varlığı, yaş, cinsiyet, geliş mevsimi, gözleme alınma ve hastaneye yatış durumlarına ait bilgiler analiz edildi. Bulgular: Çalışmamıza ortalama yaşları 5.21 ± 3.40 olan, 2303’ü kız, 3223’ü erkek, toplam 5526 akut gastroenteritli olgu alınmıştır. Tüm ol-guların %3.1’inde adenovirüs, %22.4’ünde rotavirüs etken olarak sap-tanmıştır. Adenovirüs ve rotavirüs saptanan olgularda cinsiyet anlamlı bulunmamıştır. Yaş gruplarına bakıldığında rotavirüsün en sık 7 ay-2 yaş ve 3-6 yaş dönemi çocuklarında, adenovirüsün ise adölesan dönemi hariç eşit oranda görüldüğü saptanmıştır. Rotavirüs enfeksiyonlarının kışın daha sık, adenovirüs enfeksiyonlarının ise yıl boyunca görüldü-ğü saptanmıştır. Rotavirüs olguları (n= 1240) içinde; 344 (27.7%) hasta gözleme alınmış ve 73 (5.9%) hasta hospitalize edilmiştir. Adenovirüs olguları (n= 169) içinde ise 50 (29.6%) hasta gözleme alınmış ve 10 (5.9%) hospitalize edilmiştir. Sonuç: Çalışmamız oldukça yüksek sayıda hastayı kapsamaktadır. Ro-tavirüsün mevsimsel paterni vardır, süt çocuklarında daha sıktır ve hastaneye yatışa daha çok gerek duyulur. Akut gastroenterit etkenle-ri hakkında yeterli epidemiyolojik bilgi sahibi olunursa uygulanmakta olan birçok gereksiz tetkik ve antibiyotik tedavisinden kaçınılmasının mümkün olabileceği görülmektedir.

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Cite This Article

ÇÖMÇE, M., KAFADAR, D., EROL, M., YİĞİT, Ö. (2017). A Retrospective Analysis of Rotavirus and Adenovirus Infections in Pediatric Population Admitted to Emergency Department with Acute Gastroenteritis. Çocuk Enfeksiyon Dergisi, Cilt: 11 - Sayı: 4, 153–160. https://ajindex.com/articles/160851

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References (14)

  1. Wilhelmi I, Roman E, Sánchez-Fauquier A. Viruses causing gastroenteritis. Clin Microbiol Infect 2003;9:247-62. Tekin A. The frequency of rotavirus and enteric adenovirus in children with acute gastroenteritis in Mardin. J Clin Exp Invest 2010;1:41-5.
  2. Bon F, Fascia P, Dauvergne M, et al. Prevalence of group A rotavirus, human calicivirus, astrovirus, and adenovirus type 40 and 41 infections among children with acute gastroenteritis in Dijon, France. J Clin Microbiol 1999;37:3055-8.
  3. Logan C, O’Leary JJ, O’Sullivan N. Real-time reverse transcription-PCR for detection of rotavirus and adenovirus as causative agents of acute viral gastroenteritis in children. J Clin Microbiol 2006;44:3189-95.
  4. Gray J, Vesikari T, van Damme P, et al. Rotavirus. J Pediatr Gastroenterol Nutr 2008;46(Suppl 2):S24-31. Cheng AC, McDonald JR, Thielman NM. Infectious diarrhea in developed and developing countries. J Clin Gastroenterol 2005;39:757-73.
  5. Pacini DL, Collier AM, Henderson FW. Adenovirus infections and respiratory illnesses in children in group day care. J Infect Dis 1987;156:920-6.
  6. Baskin E, Gokalp AS, Turkay S, Icagasioglu D, Toksoy HB. Adenovirus gastroenteritis. Indian Pediatr 1995;32:1128-9.
  7. Cunliffe NA, Booth JA, Elliot C, et al. Healthcare associated viral gastroenteritis among children in a large pediatric hospital, United Kingdom. Emerg Infect Dis 2010;16:55-62.
  8. Mitchell DK, Jiang X, Matson DO. Gastrointestinal infections. In: Storch GA (ed). Essentials of Diagnostic Virology. 1st ed. New York: Churchill Livingstone, 2000:79-92.
  9. Dennehy PH, Gauntlett DR, Tente WE. Comparison of nine commercial immunoassays for the detection of rotavirus in fecal specimens. J Clin Microbiol 1988;26:1630-4.
  10. Terletskaia-Ladwig E, Leinmüller M, Schneider F, Meier S, Enders M. Laboratory approaches to the diagnosis of adenovirus infection depending on clinical manifestations. Infection 2007;35:438-43.
  11. Izzuddin Poo M, Lee WS. Admission to hospital with childhood acute gastroenteritis in Kuala Lumpur, Malaysia. Med J Malaysia 2007;62:189-93.
  12. Fodha I, Chouikha A, Peenze I, et al. Identification of viral agents causing diarrhea among children in the Eastern Center of Tunisia. J Med Virol 2006;78:1198-203.
  13. Celik C, Gozel MG, Turkay H, Bakici MZ, Güven AS, Elaldi N. Rotavirus and adenovirus gastroenteritis: time series analysis. Pediatr Int 2015;57:590-6.
  14. Ozsari T, Bora G, Kaya B, Yakut K. The prevalence of rotavirus and adenovirus in the childhood gastroenteritis. Jundishapur J Microbiol 2016;9