Journals / Anestezi Dergisi / 2014 / Cilt: 22 - Sayı: 4

HYPERKALEMIA RELATED CARDIAC ARREST AFTER MASSIVE TRANSFUSION IN THE NEWBORN

YENİDOĞANDA MASİF ERİTROSİT TRANSFÜZYONUNA BAĞLI HİPERPOTASEMİ NEDENİYLE KARDİYOPULMONER ARREST

Pages
228–233
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the newborn, the K+level of the transfused blood should be measured and replacement fluids should be prepared without K+.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The recomendations for masive transfusion for the newborn are limited with the use of fresh, saline washed red blood cells (RBC).
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Key Findings & Data:The preoperative hemoglobin (Hb) level was 16 gr dL-1.
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Conclusion & Impact:In the newborn, the K+level of the transfused blood should be measured and replacement fluids should be prepared without K+.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The recomendations for masive transfusion for the newborn are limited with the use of fresh, saline washed red blood cells (RBC). In this article we report a newborn with cardiopulmonary arrest related to hyperkalemia after masive transfusion. Case: A nineteen-days-old newborn was scheduled for intracranial mass surgery. The preoperative hemoglobin (Hb) level was 16 gr dL-1. Fresh, saline washed RBCs, fresh frozen plasma and platelets were prepared for transfusion. After inhalation induction the patient was hydrated with 4 mL kg-1h-1DW5-1/4NS (7 mEqL-1 K+ in 500 mL). Radial arterial and subclavian venous canulation and invasive pressure, urine output monitorization was made. Due to massive bleeding, 250 mL RBC was transfused in 1 hour. Since the patient experienced cardiac arrest, cardiopulmonary ressusitation (CPR) was initiated. Blood gas analysis revealed pH:7, 28, HCO3:20,6 mEqL-1, pO2:212 mmHg, pCO2: 24 mmHg, SaO2: %99,4, Na+: 138 mEqL-1, K+:8,2 mEqL-1, Cl-:107 mEqL-1, Glu:477 mg dL-1, Hb:12,5 gr dL-1. Calcium gluconate, furosemide, bicarbonate and glucose/insulin infusion was initiated for the treatment of hyperkalemia along with CPR. Circulation was restored 45 min after the administration of a bolus glucose/insulin. Control K+ level was 6,9 mEqL-1. Conclusion: In the newborn, despite the use of fresh, saline washed RBCs, masive transfusion can induce hyperkalemia related cardiac arrest. A bolus glucose/insulin may be effective to treat hyperkalemia related arrest. In the newborn, the K+level of the transfused blood should be measured and replacement fluids should be prepared without K+.

Özet

Amaç: Yenidoğanın masif transfüzyon protokollerinde öneriler; taze ve yıkanmış eritrosit kullanılması ile sınırlıdır. Bu yazıda, masif tansfüzyona bağlı hiperpotasemi nedeniyle kardiyopulmoner arrest gelişen bir yenidoğan sunulmaktadır. Olgu: İntrakraniyal kitle operasyonu planlanan 19 günlük bebeğin preoperatif hemoglobin (Hb) değeri 16 gr dL-1’idi. Transfüzyon için yıkanmış taze eritrosit, plazma ve trombosit hazırlandı. Maske indüksiyonunu takiben, 4 mL kg-1saat-1 %5dekstroz-1/4 izotonik [500 ml içerisinde 7 mEqL-1 potasyum(K+)] ile hidrasyon sağlandı. Radiyal arter ve subklaviyan ven kateterizasyonu, invazif basınç ve saatlik idrar çıkışı monitorizasyonu yapıldı. Masif kanama nedeniyle 1 saatte 250 mL eritrosit verilmesini takiben asistoli gelişti. Kardiyopulmoner resüsitasyona (KPR) başlandı. Kan gazları analizinde pH:7, 28, HCO3:20,6 mEqL-1, pO2:212 mmHg, pCO2: 24 mmHg, SaO2: %99,4, Na+: 138 mEqL-1, K+: 8,2 mEqL-1, Cl-: 107 mEqL-1, Glu:477 mg dL-1, Hb:12,5 gr dL-1 ölçüldü. Hiperpotasemi saptanan hastaya; kalsiyum glukonat, sodyum bikarbonat, furosemid ve glikoz/insülin infüzyonu yapıldı, KPR sürdürüldü. Spontan dolaşım 45. dakikada ancak glikoz/insülin bolusu yapıldıktan sonra başladı. Kontrol K+ değeri 6,9 mEqL-1 ölçüldü. Sonuç: Yenidoğanda taze ve yıkanmış eritrosit kullanılmasına rağmen masif transfüzyona bağlı hiperpotasemi gelişebilir. Hiperpotasemiye bağlı kardiyak arrest tedavisinde glikoz/insülin solüsyonunun bolus uygulanması etkin olabilir. Yenidoğanlarda masif transfüzyonda, transfüze edilen kanın içerisindeki potasyum düzeyinin ölçülerek hastaya verilen potasyum miktarının belirlenmesini ve replasman sıvısının potasyumsuz hazırlanmasını öneriyoruz.

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Cite This Article

YAZICIOĞLU, D., BARAN, İ., KALE, O., ÜTEBEY, G., POLAT, R. (2014). HYPERKALEMIA RELATED CARDIAC ARREST AFTER MASSIVE TRANSFUSION IN THE NEWBORN. Anestezi Dergisi, Cilt: 22 - Sayı: 4, 228–233. https://ajindex.com/articles/160735

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