Journals / Türk Jinekolojik Onkoloji Dergisi / 2006 / Cilt: 9 Sayı: 4

ENDOMETRİAL VE ENDOSERVİKAL ADENOKARSİNOMLARIN AYIRICI TANISINDA VİMENTİN POZİTİFLİĞİNİN DEĞERİ

Pages
97–100
Publication Date
2006-10-01
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Normal endometrial tissues stained positive for vimentin while this did not count for endocervical tissues Results: Endometrial adenocarcinomas showed stronger staining for vimentin, thus can be used in the challenged differantial diagnosis of endometrial and endocervical adenocarcinomas.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: In poorly differantiated endometrial and endocervical adenocarcinoma leading to a differantial challenge;vimentin primary antibodies were used for understanding the originating tissue and with the aim of helping differantial diagnosis and treatment.
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Key Findings & Data:Material and method: During the years 1996-2002, tissue samples diagnosed at the present hospital as 42 endometrial adenocarcinoma, 15 endocervical adenocarcinoma,10 normal endometrium, and 10 normal endocervix were reevaluated and new sections were analyzed with the immunochemical method by the peroxidase technique for investigating vimentin staining properties.Findings: 38 out of 42 endometrial adenocarcinomas and 2 out of 15 endocervical adenocarcinomas were stained positive.
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Conclusion & Impact:Normal endometrial tissues stained positive for vimentin while this did not count for endocervical tissues Results: Endometrial adenocarcinomas showed stronger staining for vimentin, thus can be used in the challenged differantial diagnosis of endometrial and endocervical adenocarcinomas.
🔬Design:Makale
📍Scope:2002 Verileri
⚙️Variables:Endometrial adenokarsinoma · endoservikal adenokarsinoma · vimentin

Abstract

Aim: In poorly differantiated endometrial and endocervical adenocarcinoma leading to a differantial challenge;vimentin primary antibodies were used for understanding the originating tissue and with the aim of helping differantial diagnosis and treatment. Material and method: During the years 1996-2002, tissue samples diagnosed at the present hospital as 42 endometrial adenocarcinoma, 15 endocervical adenocarcinoma,10 normal endometrium, and 10 normal endocervix were reevaluated and new sections were analyzed with the immunochemical method by the peroxidase technique for investigating vimentin staining properties.Findings: 38 out of 42 endometrial adenocarcinomas and 2 out of 15 endocervical adenocarcinomas were stained positive. Normal endometrial tissues stained positive for vimentin while this did not count for endocervical tissues Results: Endometrial adenocarcinomas showed stronger staining for vimentin, thus can be used in the challenged differantial diagnosis of endometrial and endocervical adenocarcinomas.

Özet

Amaç: Tanı güçlüğü yaratan az diferansiye endometrial ve endoservikal adenokarsinomlarda; olgunun köken aldığı dokuyu anlamak ve ayırıcı tanı yapabilmek için Vimentin primer antikoru kullanılarak ayırıcı tanı ve tedaviye yardımcı olmaktır.Materyal Metod: Hastanemizde tanı alan 1996-2002 yılları arasında 42 Endometrial 15 endoservikal adenokarsinomalı olgu ile 10 normal endometrial, 10 normal endoservikal doku örneği yeniden değerlendirilip bu olgulara yeni kesitler yapılarak peroksidaz tekniği kullanılarak immunohistokimyasal yöntemle vimentinin boyanma özelliği araştırıldı. Bulgular: 42 endometrial adenokarsinomun 38'i, 15 endoservikal adenokarsinomun 2'si pozitif boyandı. Normal endometrial dokular vimentinle pozitif boyanırken endoservikal dokularda pozitif boyanma izlenmedi.Sonuçlar: Endometrial adenokarsinomlarda daha fazla pozitif boyanan vimentin, tanı güçlüğü yaratan endometrial ve endoservikal adenokarsinomların ayırıcı tanısında kullanılabilir.

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Cite This Article

Zergeroğlu, S., Mollamahmutoğlu, L., Reyhan, H., Aydoğdu, T. (2006). ENDOMETRİAL VE ENDOSERVİKAL ADENOKARSİNOMLARIN AYIRICI TANISINDA VİMENTİN POZİTİFLİĞİNİN DEĞERİ. Türk Jinekolojik Onkoloji Dergisi, Cilt: 9 Sayı: 4, 97–100. https://ajindex.com/articles/1603342

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