Journals / Çocuk Enfeksiyon Dergisi / 2018 / Cilt: 12 - Sayı: 4

A Rare Cause of Acute Renal Failure and Thrombocytopenia in Child: A Case Due to Hantavirus Infection

Çocuklarda Nadir Akut Böbrek Yetmezliği ve Trombositopeni Nedeni: Hantavirüs Enfeksiyonu Olgusu

Pages
156–159
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We observed a hantavirus infec-tion causing haemorrhagic fever with renal syndrome (HFRS) and corre-spondingly applied symptomatic treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:Seventeen years old yo male patient had applied to the primary care center for his complaints; fever, malaise and headache, and was he was investigated for causes thrombocytopenia of after thrombocytopenia had been detected in the workup.
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Key Findings & Data:He had hyperaemia in oropharynx, 39°C fever, noticaable malaise, thrombocytopenia and renal failure at admittance to our clinic.
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Conclusion & Impact:We observed a hantavirus infec-tion causing haemorrhagic fever with renal syndrome (HFRS) and corre-spondingly applied symptomatic treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Seventeen years old yo male patient had applied to the primary care center for his complaints; fever, malaise and headache, and was he was investigated for causes thrombocytopenia of after thrombocytopenia had been detected in the workup. He had hyperaemia in oropharynx, 39°C fever, noticaable malaise, thrombocytopenia and renal failure at admittance to our clinic. No atypic cell was seen in peripheral blood smear of the patient. Laboratory tests for parvovirus, cytomegalovirus (CMV), Epstein-Barr virus (EBV), brucella agglutination and gruber widal test and markers for hepatitis were examined and the results were neg-ative. A detailed patient history showed that we had informed that the patient had burned dead mice bodies. Serolohical investigation showed that IgG and IgM antibodies were positive in both Biot Analysis and in-direct immunofluorescence assay (IFA). We observed a hantavirus infec-tion causing haemorrhagic fever with renal syndrome (HFRS) and corre-spondingly applied symptomatic treatment.

Özet

On yedi yaşında erkek hasta 3 gündür devam eden ateş, halsizlik ve baş ağrısı şikayeti ile aile hekimliğine başvurmuş ve yapılan tetkiklerinde trombositopeni tespit edilmesi üzerine tarafımıza yönlendirilmiş. Hastanemize başvurduğunda orofarinkste hiperemi, 39°C ateş, belirgin halsizlik, trombositopeni ve böbrek yetmezliği olduğu görüldü. Hastanın periferik kan yaymasında atipik hücre görülmedi. Hastadan parvovirüs, sitomegalovirüs (CMV), Epstein-Barr virüs (EBV), hepatit belirteçleri, brusella aglütinasyon ve Gruber Widal testleri istenildi ve sonuçlar negatif saptandı. Hastadan alınan ayrıntılı anamnezde ölmüş fareleri yaktığı öğrenildi. Hantavirüsün serolojik tetkikinde hem indirekt immünfluoresan assay (IFA) hem de Biot Analysis’de IgG ve IgM antikorları pozitif saptandı. Hastada kanamalı ateş ile seyreden akut renal sendroma yol açan hantavirüs enfeksiyonu düşünüldü ve sadece semptomatik tedavi uygulandı.

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Cite This Article

ÜNAL, N., ENGİN, M. M. N., TEMİZKAN, R. C., KILIÇASLAN, Ö. (2018). A Rare Cause of Acute Renal Failure and Thrombocytopenia in Child: A Case Due to Hantavirus Infection. Çocuk Enfeksiyon Dergisi, Cilt: 12 - Sayı: 4, 156–159. https://ajindex.com/articles/159354

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References (10)

  1. Bi Z, Formenty PB, Roth CE. Hantavirus infection: a review and global update. J Infect Dev Ctries 2008;2:3-23. Çebi G. Hantavirüs infeksiyonları. Klimik Dergisi 2011;24:139-49.
  2. Heyman P, Cochez C, Korukluoglu G, Gözalan A, Uyar Y, Lundkvist A. Kıtalararası köprü; Avrupa ve Küçük Asya’nın hantavirüsleri. Bridging continents; hantaviruses of Europe and Asia Minor. Turk Hij Den Biyol Derg 2011;68:41-8.
  3. Khan AS, Ksiazek TG, Peters CJ. Hantavirus pulmonary syndrome. Lancet 1996;16;347:739-41.
  4. Vapalahti O, Mustonen J, Lundkvist A, Hettonen H, Plyusnin A, Vaheri A. Hantaviruses infections in Europe. The Lancet Infect Dis 2003;3:653-752.
  5. Guerrant RL, Walker DH, Peter F, Weller PF. Tropical infectious diseases. Principles, Pathogens and Practice. 3rd ed. Saunders Elsevier, 2011:470-80.
  6. Kaya S, Yılmaz G, Erensoy Ş, Çağlayık DY, Uyar Y, Köksal İ. Doğu Karadeniz, Giresun ilinde tespit edilen iki hantavirus enfeksiyonu olgusu. Mikrobiyol Bul 2010;44:479-87.
  7. Jonsson CB, Figueiredo LT, Vapalahti O. A global perspective on hantavirus ecology, epidemiology, and disease. Clin Microbiol Rev 2010;23:412-41. Klempa B. Hantaviruses and climate change. Clin Microbiol Infect 2009;15:518-23.
  8. Gozalan A, Kalaycıoğlu H, Uyar Y, Sevindi DF, Turkyilmaz B, Çakir V, et al. Human puumala and dobrava hantavirus infections in the Black Sea region of Turkey: a cross-sectional study. Vector Borne Zoonotic Dis 2013;13:111-8.
  9. Faber SM, Ulrich RG, Frank C, Pfaff GM, Jacob J, Krüger DH, et al. Steep rise in notified hantavirus infections in Germany. Euro Surveill 2010;15. Köksal F. Hantavirüsler. Klinik Mikrobiyoloji. 9. baskı. Ankara: Atlas Kitabevi, 2008;1501-09.
  10. Muranyi W, Bahr U, Zeier M, van der Woude FJ. Hantavirus infection. J Am Soc Nephrol 2005;16:3669-79.