Journals / Bezmiâlem Science / 2017 / Cilt: 5 - Sayı: 1

Development of Liver and Pancreas

Karaciğer ve Pankreas Gelişimi

Pages
30–35
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this manuscript, we attempted to review the morphological and functional development of the liver and pancreas with the aid of pictures obtained from various stages of prenatal and postnatal development in the organs of rats.

📌 3 Key Takeaways

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Objective & Hypothesis:The parenchyma of the liver and pancreas is derived from the endoderm, whereas the stroma is derived from the mesoderm.
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Key Findings & Data:At the 3rd-4th of development, the liver, gallbladder and bile ducts become diverticulum hepaticum that is derived from the caudal portion of the foregut.
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Conclusion & Impact:In this manuscript, we attempted to review the morphological and functional development of the liver and pancreas with the aid of pictures obtained from various stages of prenatal and postnatal development in the organs of rats.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The parenchyma of the liver and pancreas is derived from the endoderm, whereas the stroma is derived from the mesoderm. Both of them are derived from the endoderm of the foregut as the esophagus, stomach, and a part of duodenum. At the 3rd-4th of development, the liver, gallbladder and bile ducts become diverticulum hepaticum that is derived from the caudal portion of the foregut. There were inductive effects of septum transversum and cardiac mesoderm for the development of liver diverticulum. The pancreas arise from the endoderm of the foregut. The pancreas is derived from the fusion of the ventral and dorsal pancreas bulbs, which arise from the endoderm of the duodenum. The inductive effects of the notochord and dorsal aorta play a role in the development of the pancreas. In this manuscript, we attempted to review the morphological and functional development of the liver and pancreas with the aid of pictures obtained from various stages of prenatal and postnatal development in the organs of rats.

Özet

Karaciğer ve pankreasın parankiması endoderm, stroması ise mezoderm kaynaklıdır. Her iki organ da özefagus, mide ve duodenumun bir kısmının kaynaklandığı ön bağırsak endoderminden gelişirler. Karaciğer, safra kesesi ve safra kanalları 3. haftanın ortası ile 4. haftanın başında ön bağırsağın kaudal parçasından kaynaklanan diverticulum hepaticum'dan gelişmeye başlarlar. Karaciğer divertikülünün gelişmesinde septum transversumun ve kardiyak mezodermin indükleyici etkileri vardır. Pankreas da önbağırsağın endoderminden kaynaklanır. Pankreasın gelişeceği alanda duodenum endoderminden kaynaklanan dorsal ve ventral pankreas tomurcuklarının daha sonra birleşmesi ile pankreas gelişir. Pankreas gelişiminde yakın komşuluğunda bulunduğu notokorddan ve dorsal aortadan kaynaklanan sinyallerin indükleyici etkileri rol oynar. Bu kısa derlemede karaciğer ve pankreasın morfolojik ve fonksiyonel gelişimleri bu organların prenatal ve postnatal gelişimleri ile ilgili sıçanlardan elde edilen resimler eşliğinde anlatılmıştır.

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Cite This Article

EŞREFOĞLU, M., TAŞLIDERE, E., ÇETİN, A. (2017). Development of Liver and Pancreas. Bezmiâlem Science, Cilt: 5 - Sayı: 1, 30–35. https://ajindex.com/articles/159265

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