Journals / Cukurova Medical Journal / 2017 / Cilt: 42 - Sayı: 1

Toxoplasma encephalitis: an HIV/AIDS patient with cerebral mass

Toksoplazma ensefaliti: serebral kitle ile başvuran HIV/AIDS olgusu

Pages
184–188
Publication Date
2017-03-31
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The patient was identified human immunodeficiency virus positive while he was under investigation for cerebral mass lesion, The patient has fully recovered by antiprotozoal and antiretroviral therapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Toxoplasmic encephalitis is an opportunistic infection, which develops as a result of reactivation of the latent tissue cysts of Toxoplasma gondii in patients with reduced CD4+ T lymphocytes.
📊
Key Findings & Data:Amongst patients with human immunodeficiency virus or acquired immunodeficiency syndrome, toxoplasmic encephalitis is one of the leading causes of the intracerebral involvement.
💡
Conclusion & Impact:The patient was identified human immunodeficiency virus positive while he was under investigation for cerebral mass lesion, The patient has fully recovered by antiprotozoal and antiretroviral therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:HIV · AIDS · encephalitis

Abstract

Toxoplasmic encephalitis is an opportunistic infection, which develops as a result of reactivation of the latent tissue cysts of Toxoplasma gondii in patients with reduced CD4+ T lymphocytes. Amongst patients with human immunodeficiency virus or acquired immunodeficiency syndrome, toxoplasmic encephalitis is one of the leading causes of the intracerebral involvement. In this report, we present a toxoplasmic encephalitis case, who has admitted with neurological symptoms and fever. The patient was identified human immunodeficiency virus positive while he was under investigation for cerebral mass lesion, The patient has fully recovered by antiprotozoal and antiretroviral therapy.

Özet

Toksoplazma ensefaliti CD4+ T lenfosit sayısı azalmış olan hastalarda, Toxoplasma gondii’nin latent halde bulunan doku kistlerinin reaktivasyonu ile ortaya çıkan fırsatçı bir enfeksiyondur. Toksoplazma ensefaliti, insan immün yetmezlik virüsü enfeksiyonu ve kazanılmış immün yetmezlik sendromu olan hastalarda, santral sinir sistemi tutulumunun başta gelen nedenlerindendir. Bu yazıda , ateş ve nörolojik bulgularla başvuran, radyolojik incelemeler sonucunda saptanan serebral kitlenin etiyolojisi araştırılırken immün yetmezlik virüsü enfeksiyonu tanısı konan ve antiretroviral ve antiprotozoal tedavi ile tam iyileşme sağlanan bir toksoplazma ensefaliti olgusu sunulmuştur.

🔖

Cite This Article

İNAL, A. S., NAZİK, S., CANDEVİR, A., KURTARAN, B., TAŞOVA, Y., AKSU, H. S. Z. (2017). Toxoplasma encephalitis: an HIV/AIDS patient with cerebral mass. Cukurova Medical Journal, Cilt: 42 - Sayı: 1, 184–188. https://ajindex.com/articles/159140

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Luft BJ, Hafner R, Korzun AH, Leport C, Antoniskis D, Bosler EM et al. Toxoplasmic encephalitis in patients with the acquired immunodeficiency syndrome. Members of the ACTG 077p/ANRS 009 Study Team. N Engl J Med. 1993;329:995-1000
  2. Belanger F, Derouin F, Grangeot-Keros L, Meyer L. Incidence and risk factors of toxoplasmosis in a cohort of human immunodeficiency virus-infected patients: 1988-1995. HEMOCO and SEROCO Study Groups. Clin Infect Dis. 1999;28:575-81
  3. Siddiqi OK, Koralnik IJ. Neurologic diseases caused by Human Immunodeficiency Virus Type 1 and opportunistic infections. In Mandell, Douglas and Bennett’s Principles and Practice of Infectious Diseases, Bennett JE, Dolin R, Blaser MJ (editors). 8th ed. Philadelphia: Saunders. 2015:1574-89
  4. Kiderlen TR, Liesenfeld O, Schurmann D, Schneider T. Toxoplasmic encephalitis in AIDS-patients before and after introduction of highly active antiretroviral therapy (HAART). Eur Clin Microbiol Infect Dis. 2011;30:1521-5
  5. Dai L, Mahajan SD, Guo C, Zhang T, Wang W, Li T, et al. Spectrum of central nervous system disorders in hospitalized HIV/AIDS patients (2009- 2011) at a major HIV/AIDS referral center in Beijing, China. J Neurol Sci. 2014;342:88-92
  6. UK Collaborative HIV Cohort (CHIC) Study Steering Committee, Garvey L, Winston A, Walsh J, Post F, Porter K et al. HIV-associated central nervous system diseases in the recent combination antiretroviral therapy era. Eur J Neurol. 2011;18:527- 34
  7. Luft BJ, Remington JS. Toxoplasmic encephalitis in AIDS. Clin Infect Dis. 1992;15:211-22
  8. Weiss LM, Dubey JP. Toxoplasmosis: a history of clinical observations. Int J Parasitol. 2009;39:895-901
  9. Montoya JG, Boothroyd JC, Kovacs JA. Toxoplasma gondii, In: Bennett JE, Dolin R, Blaser MJ (eds). In: Bennett JE, Dolin R, Blaser MJ (eds). Principles and Practice of Infectious Diseases. Saunders, Philadelphia. 2015;3122-3153
  10. Gencer M, Cevizci S, Saçar S, Vural A, Çakır Güngör AN, Uysal A et al. Çanakkale Onsekiz Mart Üniversitesi Tıp Fakültesi Hastanesi Obstetri Polikliniğine müracaat eden gebelerde Anti- Toxoplasma gondii antikorlarının dağılımı ve risk faktörlerinin irdelenmesi. Turkiye Parazitol Derg. 2014;38:76-80
  11. Altuntaş Aydın Ö, Kumbasar Karaosmanoğlu H, Korkusuz R, Nazlıcan Ö. HIV/AIDS hastalarında Toxoplasma gondii seroprevalansı. Turkiye Parazitol Derg. 2014;35:65-7
  12. Türkiye’de AIDS vakalarının dağılımı (Haziran 2014). Hacettepe Üniversitesi HIV/AIDS Tedavi ve Araştırma Merkezi (HATAM