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Journals / Ege Klinikleri Tıp Dergisi / 2017 / Cilt: 55 - Sayı: 2

Nuchal Fold Nomogram and Relationship With He- art and Central Nervous System Anomalies

Nukhal Fold Nomogramı, Kalp ve Santral Sinir Sis- tem Hastalıkları ile İlişkisi

Aşkı ELLİBEŞ KAYA
ALPER BAŞBUĞ
Bertan AKAR
RUKİYE ADA BENDER
Ozan DOĞAN
Eray ÇALIŞKAN
Pages
65–68
DOI
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⚡ TL;DR(Too Long; Didn't Read)

No statistically significant relationship was found between nuchal fold thickness and CNS diseases (p=0.55 and p<0.05).Conclusion: The increased nuchal fold thickness in fetuses with normal karyotype does not increase with fetal heart and central nervous system diseases

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Nuchal fold thickness is the first trimester continuation of nuchal translucency in the second trimester.
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Key Findings & Data:Thick nuchal fold is important in relation to some systemic diseases, including abnormal karyotype fetus.Material-Method: This is a cross-sectional retrospective study that has been performed among 1625 singleton pregnant women with gestational ages between 16-24 weeks that has taken place in Kocaeli Medical Park Hospital from years 2011-2017.
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Conclusion & Impact:No statistically significant relationship was found between nuchal fold thickness and CNS diseases (p=0.55 and p<0.05).Conclusion: The increased nuchal fold thickness in fetuses with normal karyotype does not increase with fetal heart and central nervous system diseases
🔬Design:Research Article
📍Scope:2011-2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: Nuchal fold thickness is the first trimester continuation of nuchal translucency in the second trimester. Thick nuchal fold is important in relation to some systemic diseases, including abnormal karyotype fetus.Material-Method: This is a cross-sectional retrospective study that has been performed among 1625 singleton pregnant women with gestational ages between 16-24 weeks that has taken place in Kocaeli Medical Park Hospital from years 2011-2017. We calculated nuchal fold lenght %5, %50, %95 percentile per week and draw nuchal fold nomogram. Results: It has been shown that there is a weak positive correlation between nuchal fold thickness and the gestational week (p: 0,001, r:0,18). In 1625 analysed patients, 50 patients had cardiovascular system (CVS) diseases and 32 patients had central nervous system (CNS) diseases. There was not a statistically significant relationship between nuchal fold thickness and CVS diseases (p= 0.98 and p<0.05). No statistically significant relationship was found between nuchal fold thickness and CNS diseases (p=0.55 and p<0.05).Conclusion: The increased nuchal fold thickness in fetuses with normal karyotype does not increase with fetal heart and central nervous system diseases

Özet

Amaç: Nukhal fold kalınlığı birinci trimesterda ölçülen ense saydamlığının ikinci trimesterda devamı niteliğindedir. Özellikle anormal karyotip olan vakalar dâhil edilirse bazı sistemik hastalıklarla ilişkisi ve detaylı ultrasound için bir uyarı niteliği taşıması açısından önemlidir. Yöntem: Çalışmamız 2011-2017 yılları arasında Kocaeli Medikal Park hastanesinde takipleri yapılmış 16-24 haftalar arasındaki 1625 tekil normal karyotipli gebelerden oluşmaktadır. Gebelerin detaylı ultrasonografileri yapıldı. Her hafta için %5, %50, %95 percentil nukhal fold kalınlıkları hesaplanarak nukhal fold nomogramı oluşturuldu. Bulgular: Gebelik yaşı ile nukhal fold kalınlığı arasında pozitif korelasyon tespit edildi (p: 0,001, r:0,18). Tüm hastalar içinde 50 fetusta kardiak hastalık, 32 fetusta santral sinir sistemi patolojisi saptandı. Nukhal fold kalınlığı ile kardiovasküler hastalık arasında istatistiksel olarak anlamlı bir ilişki saptanmadı (p= 0.98 and p<0.05). Nukhal fold kalınlığı ile santral sinir sistemi hastalıkları arasında da istatistiksel olarak anlamlı bir ilişki saptanmadı (p=0.55 and p<0.05).Sonuç: Normal karyotipli fetuslarda nukhal fold kalınlığındaki artış, fetal kalp ve santral sinir sistemi hastalıkları ile artış göstermemektedir

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Cite This Article

KAYA, A. E., BAŞBUĞ, A., AKAR, B., BENDER, R. A., DOĞAN, O., ÇALIŞKAN, E. (2017). Nuchal Fold Nomogram and Relationship With He- art and Central Nervous System Anomalies. Ege Klinikleri Tıp Dergisi, Cilt: 55 - Sayı: 2, 65–68. https://ajindex.com/articles/159114

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