Journals / ANKEM Dergisi / 2012 / Cilt: 26 - Sayı: 3

Macrolide-lincosamide-streptogramin B (MLS B ) resistance phenotypes in staphylococci isolated from clinical samples

Klinik örneklerden izole edilen stafilokok suşlarında makrolid- linkozamid-streptogramin B (MLS B ) direnç fenotipleri

Pages
116–119
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Out of 100 isolates, eighty seven had inducible MLS B(five MSSA, 66 MRCoNS,16 MSCoNS); nine had structural (one MRSA, eight MSCoNS) and four (two MSCoNS, two MRCoNS) had efflux type resistance.

📌 3 Key Takeaways

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Objective & Hypothesis:The task of Clinical Microbiology Laboratories also includes to show the macrolide-lincosamide-streptogramin B (MLS B) resistance in routine practice caused by community and hospital acquired staphylococcal strains.
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Key Findings & Data:One hundred Staphylococcus strains, 6 Staphylococcus aureus and 94 coagulase negative staphylococci [CoNS], isolated from clinical specimens in 2010-2011 at Tepecik Education and Research Hospital were included in this study.
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Conclusion & Impact:Out of 100 isolates, eighty seven had inducible MLS B(five MSSA, 66 MRCoNS,16 MSCoNS); nine had structural (one MRSA, eight MSCoNS) and four (two MSCoNS, two MRCoNS) had efflux type resistance.
🔬Design:Research Article
📍Scope:2010-2011 Verileri
⚙️Variables:Domain Parameters

Abstract

The task of Clinical Microbiology Laboratories also includes to show the macrolide-lincosamide-streptogramin B (MLS B) resistance in routine practice caused by community and hospital acquired staphylococcal strains. The aim of this study was to evaluate the MLS B type resistance and their phenotypes in staphylococcal strains isolated from various clinical samples. One hundred Staphylococcus strains, 6 Staphylococcus aureus and 94 coagulase negative staphylococci [CoNS], isolated from clinical specimens in 2010-2011 at Tepecik Education and Research Hospital were included in this study. Methicillin resistan - ce was detected by cefoxitin susceptibility using disk diffusion method. MLS B resistance was shown by D-test method. One of the six S.aureus strains was identified as methicillin resistant (MRSA), five as methicillin susceptible (MSSA); 76 of the CoNS isolates were methicillin resistant (MRCoNS), and 18 were methicillin susceptible (MSCoNS). Out of 100 isolates, eighty seven had inducible MLS B(five MSSA, 66 MRCoNS,16 MSCoNS); nine had structural (one MRSA, eight MSCoNS) and four (two MSCoNS, two MRCoNS) had efflux type resistance.

Özet

Tedavisi sorun oluşturan toplum ve hastane kaynaklı dirençli stafilokok infeksiyonlarında, mikrobiyoloji laboratuvarlarının görevi makrolid-linkozamid-streptogramin B direncini de ortaya koymaktır. Bu çalışmada, çeşitli klinik örneklerden izole edilen stafilokok suşlarında MLS B direnci ve fenotiplerinin belirlenmesi amaçlanmıştır. İzmir Tepecik Eğitim ve Araştırma Hastanesi İnfeksiyon Hastalıkları Kliniği Mikrobiyoloji Laboratuvarında 2010-2011 yıllarında klinik örneklerden tanımlanan toplam 100 stafilokok suşu [6 Staphylococcus aureus ve 94 koagülaz negatif stafilokok (KNS)] çalışmaya dâhil edilmiştir. Metisilin direnci sefoksitin diski kullanılarak disk difüzyon yöntemiyle saptanmış, MLS B direnci ise D test yöntemiyle araştırılmıştır. Altı S.aureus suşunun biri metisiline dirençli (MRSA), beşi metisiline duyarlı (MSSA); KNS suşlarının 76’sı metisiline dirençli (MRKNS), 18’i metisiline duyarlı (MSKNS) bulunmuştur. Çalışmaya dahil edilen 100 stafilokok suşunun 87’sinde indülenebilir MLS B (beşi MSSA, 66’sı MRKNS, 16’sı MSKNS); dokuzunda yapısal MLS B (biri MRSA, sekizi MRKNS), dördünde efluks tipi direnç (ikisi MSKNS, ikisi MRKNS suşlarında) fenotipi tespit edilmiştir.

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Cite This Article

ŞAMLIOĞLU, P. (2012). Macrolide-lincosamide-streptogramin B (MLS B ) resistance phenotypes in staphylococci isolated from clinical samples. ANKEM Dergisi, Cilt: 26 - Sayı: 3, 116–119. https://ajindex.com/articles/156757

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