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Journals / Ege Klinikleri Tıp Dergisi / 2018 / Cilt: 56 - Sayı: 3

Non IgE Mediated Food Allergies in Children

Çocuklarda IgE Aracılı Olmayan Besin Alerjileri

İrem TURGAY YAMUR
Özge YILMAZ-TOPAL
Emine DİBEK MISIRLIOĞLU
Pages
154–163
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Besin alerjileri İmmünoglobulin E (IgE) aracılı, non-IgE aracılı (IgE aracılı olmayan) ve her ikisinin bir- likte görüldüğü alerjik reaksiyonlar olarak gruplanır (1)

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Non-IgE mediated gastrointestinal food allergies are food protein induced enterocolitis syndrome, aller- gic proctocolitis, food protein induced enteropathy and celiac disease.
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Key Findings & Data:They may also affect skin (derma- titis herpetiformis) and lungs (Heiner’s syndrome).
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Conclusion & Impact:Besin alerjileri İmmünoglobulin E (IgE) aracılı, non-IgE aracılı (IgE aracılı olmayan) ve her ikisinin bir- likte görüldüğü alerjik reaksiyonlar olarak gruplanır (1)
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Non-IgE mediated gastrointestinal food allergies are food protein induced enterocolitis syndrome, aller- gic proctocolitis, food protein induced enteropathy and celiac disease. They may also affect skin (derma- titis herpetiformis) and lungs (Heiner’s syndrome). Non-IgE mediated gastrointestinal food allergies are typically present in infancy and are triggered most commonly by cow’s milk protein. These disorders are differentiated by clinical features and course patterns. The usual presenting features are vomiting with lethargy and dehydration in FPIES; bloody and mucous stools in well appearing infant in FPIAP; and diarrhea with malabsorption and failure to thrive in FPE. Non-IgE mediated food allergies are diagnosed by a consistent history of food allergy, resolution of symptoms after elimination of the offending food and confirmatory lab-oratory tests. The basis of tre- atment relies on the avoidance of the allergenic food. Besin alerjileri tetikleyen besinin alınmasıyla gelişen anormal immünolojik yanıtlar sonucunda ortaya çı- kar. Besin alerjileri İmmünoglobulin E (IgE) aracılı, non-IgE aracılı (IgE aracılı olmayan) ve her ikisinin bir- likte görüldüğü alerjik reaksiyonlar olarak gruplanır (1)

Özet

Non-IgE aracılı besin alerjileri besin proteini ilişkili enterokolit sendromu (BPİES), besin proteini ilişkili alerjik proktokolit (BPİAP), besin proteini ilişkili enteropati (BPE), çölyak hastalığıdır. Deri (dermatitis herpetiformis) ve solunum sistemini (Heiner Sendromu) de etkileyebilmektedir. BPİES, BPİAP ve BPE genellikle süt çocukluğu döneminde görülür, en sık tetikleyici gıda inek sütüdür. Hastalar klinik özellikleri ve seyirleri ile ayırt edilebilir. Klinik bulgular BPIES’te kusma, letarji, dehidratasyon, BPİAP’ta kanlı mukuslu gaita, BPE’de malabsorpsiyon, diyare ve gelişme geriliğidir. Non-IgE aracılı besin alerjilerinde tanı; besin alerjisi ile uyumlu öykü, sorumlu besinin eliminasyonu ile klinik düzelme ve destekleyici laboratuvar bulgularının olması ile konur. Tedavinin temelini ise sorumlu besinden kaçınmak oluşturmaktadır.

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Cite This Article

YAMUR, İ. T., YILMAZ-TOPAL, Ö., MISIRLIOĞLU, E. D. (2018). Non IgE Mediated Food Allergies in Children. Ege Klinikleri Tıp Dergisi, Cilt: 56 - Sayı: 3, 154–163. https://ajindex.com/articles/156668

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