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Journals / ENT Updates / 2016 / Cilt: 6 - Sayı: 2

Rekürren aftöz stomatitli hastalarda bir tanıindikatörü olarak ortalama trombosit hacmi ve nötrofil/lenfosit oranının değerlendirilmesi

Evaluation of mean platelet volume and neutrophil to lymphocyte ratio as a diagnostic indicator in patients with recurrent aphthous stomatitis

Murat ŞEREFLİCAN
BETÜL ŞEREFLİCAN
Bengü TUMAN
Nadir GÖKSÜGÜR
Selcan KESGİN
Veysel YURTTAŞ
Pages
82–86
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion:It was shown that MPV can be used as a diagnostic indicator in patients with RAS

📌 3 Key Takeaways

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Objective & Hypothesis:Objective:Recurrent aphthous stomatitis (RAS) is a chronic inflammatory disease of oral mucosa characterized by recurrent painfululcers.
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Key Findings & Data:Mean platelet volume (MPV) indicates thrombocytic activation, while neutrophil/lymphocyte rate (NLR) is an indicator of chronic inflammation, and both of them can be measuredduring routine whole blood analysis.
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Conclusion & Impact:Conclusion:It was shown that MPV can be used as a diagnostic indicator in patients with RAS
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective:Recurrent aphthous stomatitis (RAS) is a chronic inflammatory disease of oral mucosa characterized by recurrent painfululcers. Despite it is a condition seen frequently, its etiology andpathogenesis are not known fully. Its etiology is reportedly idiopathic or multifactorial. Mean platelet volume (MPV) indicates thrombocytic activation, while neutrophil/lymphocyte rate (NLR) is an indicator of chronic inflammation, and both of them can be measuredduring routine whole blood analysis. The aim of this study is to investigate MPV and NLR values in patients with RAS and the controlgroup. Methods:A total of 39 patients with RAS and 34 control subjectswere included in the study. Results: When the patient and the control groups were compared,MPV, ESR, CRP and vitamin B12 values were significantly higher inthe patient group while NLR, WBC, hemoglobin, neutrophil and lymphocyte values were not significantly different between both groups. Conclusion:It was shown that MPV can be used as a diagnostic indicator in patients with RAS

Özet

Amaç: Rekürren aftöz stomatit (RAS) oral mukozanın tekrarlayan,ağrılı ülserlerle karakterize, kronik inflamatuar bir hastalığıdır. Sıkgörülen bir durum olmasına karşın etyolojisi ve patogenezi tam olarak bilinmemektedir. Etyolojisinin idiyopatik veya multifaktöryel olduğu belirtilmektedir. Ortalama trombosit hacmi (MPV) trombositaktivasyonunu gösteren, nötrofil lenfosit oranı (NLR) ise kronik inflamasyon göstergesi olan ve her ikisi de rutin tam kan tetkiklerindeölçülebilen değerlerdir. Bu çalışmanın amacı RAS'lı ve kontrol grubuhastalardaki MPV ve NLR değerlerini araştırmaktır. Yöntem:Bu çalışmaya 39 RAS'ı bulunan ve 34 kontrol grubu hastadahil edildi. Bulgular:Hasta ve kontrol grubu karşılaştırıldığında MPV, ESR, CRP,vitamin B12 değerlerinin hasta grubunda kontrol grubuna göre anlamlı derecede yüksek çıktı ve NLR, WBC, hemoglobin, nötrofil, lenfositdeğerleri arasında her iki grup arasında anlamlı fark bulunmadı. Sonuç:Ortalama trombosit hacminin, RAS'lı hastalarda tanısal birgösterge olabileceği ortaya konuldu

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Cite This Article

ŞEREFLİCAN, M., ŞEREFLİCAN, B., TUMAN, B., GÖKSÜGÜR, N., KESGİN, S., YURTTAŞ, V. (2016). Rekürren aftöz stomatitli hastalarda bir tanıindikatörü olarak ortalama trombosit hacmi ve nötrofil/lenfosit oranının değerlendirilmesi. ENT Updates, Cilt: 6 - Sayı: 2, 82–86. https://ajindex.com/articles/154567

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References (16)

  1. Chavan M, Jain H, Diwan N, Khedkar S, Shete A, Durkar S. Recurrent aphthous stomatitis: a review. J Oral Pathol Med 2012;41:577–83
  2. Brailo V, Boras VV, Cekic-Arambasin A. Recurrent aphthous ulcerations: analysis of predisposing factors in 68 patients. [Article in Croatian] Lijec Vjesn 2007;129:4–7
  3. Scully C, Gorsky M, Lozada-Nur F. The diagnosis and management of recurrent aphthous stomatitis: a consensus approach. J Am Dent Assoc 2003;134:200–7
  4. Ekiz O, Balta I, Sen BB, et al. Mean platelet volume in recurrent aphthous stomatitis and Behçet disease. Angiology 2014;65: 161–5
  5. Kapsoritakis AN, Koukourakis MI, Sfiridaki A, et al. Mean platelet volume: a useful marker of inflammatory bowel disease activity. Am J Gastroenterol 2001;96:776–81
  6. Yazici S, Yazici M, Erer B, Calik Y, Ozhan H, Ataoglu S. The platelet indices in patients with rheumatoid arthritis: mean platelet volume reflects disease activity. Platelets 2010;21:122–5
  7. Balta S, Demirkol S, Cakar M, Celik T. Mean platelet volume as a surrogate marker of low-grade inflammation in osteoarthritis. Platelets 2014;25:643–4
  8. Zahorec R. Ratio of neutrophil to lymphocyte counts – rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy 2001;102:5–14
  9. Taflo¤lu ‹, Sert D, Colak N, Uzun A, Songur M, Ecevit A. Neutrophil-lymphocyte ratio and the platelet-lymphocyte ratio predict the limb survival in critical limb ischemia. Clin Appl Thromb Hemost 2014;20:645–50
  10. Biyik M, Ucar R, Solak Y, et al. Blood neutrophil-to-lymphocyte ratio independently predicts survival in patients with liver cirrhosis. Eur J Gastroenterol Hepatol 2013;25:435–41
  11. McLeod RI. Drug-induced aphthous ulcers. Br J Dermatol 2000;143:1133–9
  12. Landsberg R, Fallon M, Insel R. Alterations of T helper / inducer and T Supresser / inducer cells in patients with recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol 1990;69:205– 8
  13. Rogers RS 3rd. Recurrent aphthous stomatitis in the diagnosis of Behçet's disease. Yonsei Med J 1997;38:370–9
  14. Preeti L, Magesh K, Rajkumar K, Karthik R. Recurrent aphthous stomatitis. J Oral Maxillofac Pathol 2011;15:252–6
  15. Slebioda Z, Szponar E, Kowalska A. Etiopathogenesis of recurrent aphthous stomatitis and the role of immunologic aspects: literature review. Arch Immunol Ther Exp (Warsz) 2014;62: 205–15
  16. Geri G, Terrier B, Rosenzwajg M, et al. Critical role of IL-21 in modulating TH17 and regulatory T cells in Behçet