Sigara İçen ve İçmeyen Sağlıklı Kişilerde Serum Lipid Peroksid ve Lipid Parametrelerinin Araştırılması

Özet

SüleymanDemirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 1996 Haziran; 3(2) Sigara İçen ve İçmeyen Sağlıklı Kişilerde Serum Lipid Peroksid ve Lipid Parametrelerinin Araştırılması Süleyman Kaleli Mahmut Ay Osman Çağlayan Ahmet Akkaya Fatih Gültekin Özet Sigara içen 30 ve sigara içmeyen 30 olmak üzere toplam 60 yetişkin erkeğin serumlarında HDL-C, HDL2-C, HDL3-C, LDL-C, total kolesterol (TC), trigliserid (TG) ve lipid peroksit analizleri yapıldı. Analiz sonuçları sigara içenler ve kontrol grubu sırasıyla: HDL-C: (36.5±3.6)-(41.5±7.8) mg/dl, HDL2-C: (3.53±1.7)-(6.78±4.27) mg/dl, HDL3-C: (33.21 ±4.15)-(34.57±5.23) mg/dl, LDL-C: (136.14^28.59)-(93.03±29.06) mg/dl, TC: (170.ü±40.51)-(160.26-33.83) mg/dl, TG: (169.4±53.58)-(115.89±44.9) mg/dl, Lipid peroksit (2.98±1.3)-(2.39±0.59) nmol/ml ol ar ak saptanmıştır. Sigara içiminin HDL-C ve HDL2-C'ü anlamlı ölçüde azaltırken (sırasıylap 0.05) gözlenmiştir. Anahtar Kelimeler: Sigara, Lipid, LipidPeroksidasyonu. Abstract Determinations of Serum Lipid Peroxide Levels and Lipid Paranıeters in Smokers and Non-Smokers in 30 smokers and 30 non-smokers (60 healthy male), serum HDL-C, HDLrC, HDL3-C, LDL-C, total cholesterol (TC), triglyceride (TG) and lipid peroxide levels were analysed. The results were (36.5±3.6)-(41.5±7.8) mg/dl, (3.53±1.7)-(6.78±4.27) mg/dl, (33.21±4.15)-(34.57±5.23) mg/dl, (136.14±28.59)-(93.03^29.06) mg/dl, (170.0±40,51)-(160.26±33.83) mg/dl, (169.4±53.58)-(115.89±44.9) mg/dl, (2.98±1.3)-(2.39±0.59) nmol/ml for HDL-C, HDL2-C, HDL3-C, LDL-C, TC, TG and lipid peroxide, respectively. in smokers, the levels of HDL-C and HDLrC were found to be decreased (p<0.05, p<0.01, respectively), LDL-C, TG and lipid peroxide levels were noted to be increased (p<0.001, p<0.001, p<0.05, respectively) and HDL3-C and TC levels were found to be unchanged. Key Words: Cigarette, Lipid, Lipid Peroxidation.