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Journals / Sağlık Profesyonelleri Araştırma Dergisi / 2026 / Sayı: 2026

Hypertension and Beyond; Exploring Fatigue, Dyspnea, and Physical Function: a cohort study

Hipertansiyon ve Ötesi; Yorgunluk, Nefes Darlığı ve Fiziksel Fonksiyonların İncelenmesi: Bir Kohort Çalışması

Cansu Şahbaz Pirinççi(Sağlık Bilimleri Üniversitesi)0000-0002-3921-0721
Emine Cihan(SELCUK UNIVERSITY)0000-0003-0699-3771
Muhammed Arca(İSTİNYE ÜNİVERSİTESİ)0000-0001-8104-4985
Elif Dilara Durmaz(İSTİNYE ÜNİVERSİTESİ)0000-0001-5670-8890
Muhammed Süleymanoğlu(UNIVERSITY OF HEALTH SCIENCES, DİYARBAKIR GAZİ YAŞARGİL HEALTH RESEARCH CENTER)0000-0003-1128-9455
Pages
64–70
Publication Date
2026-03-09
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusions: The increased level of fatigue negatively affected the psychological status of the patients, and increased dyspnea at high blood pressure also affected ambulation-related activities of daily living compared to normotensive people of similar age.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Hypertension can negatively affect physical performance, causing increased fatigue and dyspnea during daily activities.
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Key Findings & Data:Material and Methods: The study was conducted with 60 participants diagnosed with hypertension and 60 normotensive (non-hypertensive), totaling 120 participants.
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Conclusion & Impact:Conclusions: The increased level of fatigue negatively affected the psychological status of the patients, and increased dyspnea at high blood pressure also affected ambulation-related activities of daily living compared to normotensive people of similar age.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Dispne · Yorgunluk · Fonksiyonel Kapasite

Abstract

Objective: Hypertension can negatively affect physical performance, causing increased fatigue and dyspnea during daily activities. The aim of our study was to investigate fatigue, dyspnea and functional capacity of people diagnosed with hypertension. Material and Methods: The study was conducted with 60 participants diagnosed with hypertension and 60 normotensive (non-hypertensive), totaling 120 participants. Fatigue was assessed with the Fatigue Impact Scale and Fatigue Severity Scale, dyspnea with the Modified Medical Research Council Dyspnea Scale (mMRC), and functional capacity with the 6 Minute Walking Test. Results: Psychological scores from the subscales of the FIS were statistically significantly lower in the normotensive group compared to the hypertensive group (p = 0.014). When the mMRC dyspnea scale was evaluated, a statistically significant difference was obtained between the groups in terms of distribution (p<0.001). The results of the study show that hypertensive subjects have reduced functional exercise capacity. Conclusions: The increased level of fatigue negatively affected the psychological status of the patients, and increased dyspnea at high blood pressure also affected ambulation-related activities of daily living compared to normotensive people of similar age.

Özet

Amaç: Hipertansiyon, fiziksel performansı olumsuz etkileyerek günlük aktiviteler sırasında yorgunluk ve nefes darlığının artmasına neden olabilir. Çalışmamızın amacı, hipertansiyon tanısı konmuş kişilerin yorgunluk, nefes darlığı ve fonksiyonel kapasitelerini araştırmaktı. Gereç ve Yöntem: Çalışma, hipertansiyon tanısı konmuş 60 katılımcı ve normotansif (hipertansif olmayan) 60 katılımcı olmak üzere toplam 120 katılımcı ile gerçekleştirilmiştir. Yorgunluk, Yorgunluk Etki Ölçeği ve Yorgunluk Şiddet Ölçeği ile, nefes darlığı, Modifiye Tıbbi Araştırma Konseyi Nefes Darlığı Ölçeği (mMRC) ile ve fonksiyonel kapasite, 6 Dakikalık Yürüme Testi ile değerlendirilmiştir. Sonuçlar: FIS alt ölçeklerinden elde edilen psikolojik puanlar, hipertansif gruba kıyasla normotansif grupta istatistiksel olarak anlamlı derecede daha düşüktü (p = 0,014). mMRC nefes darlığı ölçeği değerlendirildiğinde, gruplar arasında dağılım açısından istatistiksel olarak anlamlı bir fark elde edildi (p<0,001). Çalışmanın sonuçları, hipertansif deneklerin fonksiyonel egzersiz kapasitelerinin azaldığını göstermektedir. Sonuçlar: Artan yorgunluk düzeyi, hastaların psikolojik durumunu olumsuz etkilemiş ve yüksek tansiyonda artan dispne, benzer yaştaki normotansif kişilere kıyasla, yürümeyle ilgili günlük yaşam aktivitelerini de etkilemiştir.

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Cite This Article

Pirinççi, C. Ş., Cihan, E., Arca, M., Durmaz, E. D., Süleymanoğlu, M. (2026). Hypertension and Beyond; Exploring Fatigue, Dyspnea, and Physical Function: a cohort study. Sağlık Profesyonelleri Araştırma Dergisi, Sayı: 2026, 64–70. https://doi.org/10.57224/jhpr.1817137

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References (21)

  1. James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;311(5):507-20.
  2. Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, et al. 2020 International Society of Hypertension Global Hypertension Practice Guidelines. Hypertension. 2020;75(6):1334-57.
  3. Hardas SP, Savant N, Mulay P. One-year clinical outcomes in patients with very small coronary artery disease treated with drug-eluting stents: An observational study in the Indian population. Indian Heart J. 2021;73(6):729-32.
  4. Lee YYL, Jelinek HF, McLachlan CS. Systolic blood pressure but not electrocardiogram QRS duration is associated with heart rate variability (HRV): a cross-sectional study in rural Australian non-diabetics. Clin Hypertens. 2017;23:9.
  5. Feldman PH, McDonald MV, Trachtenberg M, Trifilio M, Onorato N, Sridharan S, et al. Reducing Hypertension in a Poststroke Black and Hispanic Home Care Population: Results of a Pragmatic Randomized Controlled Trial. Am J Hypertens. 2020;33(4):362-70.
  6. Liu MY, Li N, Li WA, Khan H. Association between psychosocial stress and hypertension: a systematic review and meta-analysis. Neurol Res. 2017;39(6):573-80.
  7. Myers J, Prakash M, Froelicher V, Do D, Partington S, Atwood JE. Exercise capacity and mortality among men referred for exercise testing. N Engl J Med. 2002;346(11):793-801.
  8. Armutlu K, Keser İ, Korkmaz N, Akbıyık Dİ, Sümbüloğlu V, Güney Z, et al. Psychometric study of Turkish version of Fatigue Impact Scale in multiple sclerosis patients. J Neurol Sci 2007;255(1-2):64-8.
  9. Armutlu K, Korkmaz NC, Keser I, Sumbuloglu V, Akbiyik DI, Guney Z, et al. The validity and reliability of the Fatigue Severity Scale in Turkish multiple sclerosis patients. Int J Rehabil Res. 2007;30(1):81-5.
  10. Munari AB, Gulart AA, Dos Santos K, Venâncio RS, Karloh M, Mayer AF. Modified Medical Research Council Dyspnea Scale in GOLD Classification Better Reflects Physical Activities of Daily Living. Respir Care. 2018;63(1):77-85.
  11. Enright PL. The six-minute walk test. Respir Care. 2003;48(8):783-5.
  12. Joyner MJ, Wallin BG, Charkoudian N. Sex differences and blood pressure regulation in humans. Exp Physiol. 2016;101(3):349-55.
  13. Brown CD, Higgins M, Donato KA, Rohde FC, Garrison R, Obarzanek E, et al. Body mass index and the prevalence of hypertension and dyslipidemia. Obes Res. 2000 Dec;8(9):605-19.
  14. Mancia G, Ambrosioni E, Rosei EA, Leonetti G, Trimarco B, Volpe M, et al. Blood pressure control and risk of stroke in untreated and treated hypertensive patients screened from clinical practice: results of the ForLife study. J Hypertens. 2005;23(8):1575-81.
  15. Fagard RH. Physical activity, physical fitness and the incidence of hypertension. J Hypertens. 2005;23(2):265-7.
  16. Thurston TS, Weavil JC, Wan HY, Supiano MA, Kithas PA, Amann M. Hypertension restricts leg blood flow and aggravates neuromuscular fatigue during human locomotion in males. Am J Physiol Regul Integr Comp Physiol. 2024;327(5):517-24.
  17. Skalska P, Kurpaska M, Banak M, Krzesiński P. Hypertensive women with dyspnea exhibit an unfavorable central blood pressure response to exercise. Hypertens Res. 2025;48(5):1759-67.
  18. d'Elia HF, Rehnberg E, Kvist G, Ericsson A, Konttinen Y, Mannerkorpi K. Fatigue and blood pressure in primary Sjogren's syndrome. Scand J Rheumatol. 2008;37:284-92.
  19. Pagani M, Lucini D, Mela GS, Langewitz W, Malliani A. Sympathetic overactivity in subjects complaining of unexplained fatigue. Clin Sci (Lond). 1994;87(6):655-61.
  20. D'Souza AW, Stickland MK. Putting the HYPE in hypertension: peripheral chemoreflex constraint of skeletal muscle blood flow. J Physiol. 2024;24.
  21. Paffenbarger RS Jr, Wing AL, Hyde RT, Jung DL. Physical activity and incidence of hypertension in college alumni. Am J Epidemiol. 1983;117(3):245-57.