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Journals / Pediatric Practice and Research / 2026 / Volume: 11 Issue: 2

The Relationship Between ABO-Rh Blood Types and Disease Severity in Children with COVID-19 Infection

COVID-19 Tanılı Çocuklarda ABO-Rh Kan Grupları ile Hastalık Şiddeti Arasındaki İlişki

Edanur Yeşil(MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-8926-9959
Ali Özdemir(Mersin City Training and Research Hospital)0000-0001-7340-0409
Meltem Erdem(Ankara Etlik City Training and Research Hospital)0000-0002-9038-9165
Berfin Özgökçe Özmen(Mersin City Training and Research Hospital)0000-0001-5054-8507
Mehtap Akça(Mersin University Medical Faculty)0000-0002-6397-2320
Beyhan Bülbül(Samsun City Training and Research Hospital)0000-0002-5720-1212
Burcu Bursal Duramaz(Kanuni Sultan Süleyman Süleyman Research and Training Hospital)0000-0002-4098-947X
Güldane Dikme(MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ)0009-0001-8747-3972
Aslınur Meryem Karagüven(İstanbul Bezmialem University, Department of Pediatrics)0000-0002-7905-3484
Hakan Yazan(İstanbul Bezmialem University)0000-0002-7680-4000
Velat Şen(DİCLE ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-9232-5982
Kamil Yılmaz(DİCLE ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0001-5137-0501
Erkan Çakır(İstanbul Bezmialem University)0000-0002-1438-7854
Ozden Turel(İstanbul Bezmialem University)0000-0002-6535-4147
Solmaz Çelebi(ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-3536-0263
Mustafa Kemal Hacımustafaoğlu(ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-4646-660X
Necdet Kuyucu(MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-6721-4105
Pages
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Publication Date
2023-07-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusions: In our study with pediatric population, no difference was detected between blood types and/or Rhesus condition and COVID-19 severity.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The purpose of this study was to evaluate correlation between ABO, Rhesus (Rh) blood type and the disease severity status, pneumonia status in children with COVID-19.
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Key Findings & Data:Material and Methods: This is a multicenter study of all children 0.05).
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Conclusion & Impact:Conclusions: In our study with pediatric population, no difference was detected between blood types and/or Rhesus condition and COVID-19 severity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:ABO blood group · COVID-19 · risk factors

Abstract

Aim: The purpose of this study was to evaluate correlation between ABO, Rhesus (Rh) blood type and the disease severity status, pneumonia status in children with COVID-19. Material and Methods: This is a multicenter study of all children 0.05). Conclusions: In our study with pediatric population, no difference was detected between blood types and/or Rhesus condition and COVID-19 severity.

Özet

Amaç: Bu çalışmanın amacı, COVID-19'lu çocuklarda ABO, Rhesus (Rh) kan grubu ile hastalık şiddet durumu, pnömoni durumu arasındaki ilişkiyi değerlendirmektir. Materyal ve Metot: Bu, COVID-19 enfeksiyonu olan 18 yaşından küçük tüm çocukların elektronik tıbbi dosyalarından retrospektif olarak incelendiği çok merkezli bir çalışmadır. Hastalar asemptomatik, hafif hastalık ve radyolojik olarak kanıtlanmış pnömoni olarak üç kategoriye ayrıldı. COVID-19 hastaları ve kontrol grubu arasındaki ABO ve Rh kan grubu dağılımındaki farklılıklar analiz edildi. Bulgular: Çalışmaya 5 farklı hastaneden medyan yaşı 12 (1-18) olan toplam 1026 hasta dahil edildi. Asemptomatik hastalar %32 (n=323), hafif semptomatik %59 (n=607) ve radyolojik olarak kanıtlanmış pnömoni tüm vakaların %9'u (n=96) idi. Kontrol grubu olarak toplam 1600 çocuk dahil edildi. Kontrol kan grupları ile COVID-19 hastalarının kan grubu dağılımı arasında istatistiksel olarak anlamlı fark yoktu (p=0,062). Laboratuvar özellikleri değerlendirildiğinde hastaların klinik şiddeti arttıkça; yaş (p=0,012), lökosit sayısı (p=0,013), CRP (p=0,002), ferritin (p=0,0001) ve D-dimer (p=0,049) arttı; ve lenfosit sayıları azaldı (p=0,027). Klinik şiddet durumu ile kan grupları (ABO ve Rh) ve sadece ABO durumu arasında istatistiksel olarak anlamlı fark yoktu (sırasıyla p=0.126, p=0.630). Klinik ve laboratuvar verileri Rh durumuna göre değerlendirildiğinde istatistiksel olarak anlamlı fark bulunmadı (p>0,05). Sonuç: Pediatrik popülasyon ile yaptığımız çalışmamızda kan grupları ve/veya Rhesus durumu ile COVID-19 şiddeti arasında fark saptanmadı.

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Cite This Article

Yeşil, E., Özdemir, A., Erdem, M., Özmen, B. Ö., Akça, M., Bülbül, B., Duramaz, B. B., Dikme, G., Karagüven, A. M., Yazan, H., Şen, V., Yılmaz, K., Çakır, E., Turel, O., Çelebi, S., Hacımustafaoğlu, M. K., Kuyucu, N. (2023). The Relationship Between ABO-Rh Blood Types and Disease Severity in Children with COVID-19 Infection. Pediatric Practice and Research, Volume: 11 Issue: 2. https://doi.org/10.21765/pprjournal.1320697

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