Journals / Bezmiâlem Science / 2018 / Cilt: 6 - Sayı: 3

Comparing Mean Platelet Volume Values in Patients with Recurrent Aphthous Stomatitis and Patients with Behcet’s Disease

Tekrarlayan Oral Aft ve Behçet Hastalarında Ortalama Trombosit Hacmi Değerlerinin Karşılaştırılması

Pages
196–199
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although in some studies, MPV was high in patients with Behcet’s disease, in our study, we did not observe any statistically significant difference in patients with Behcet’s disease, patients with recurrent aphthous stomatitis, and control group.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Platelets play an important role in the pathogenesis of disorders associated with the local or systemic inflammation.
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Key Findings & Data:Age, sex, MPV values, vitamin B12, and TSH were retrospectively recorded.
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Conclusion & Impact:Although in some studies, MPV was high in patients with Behcet’s disease, in our study, we did not observe any statistically significant difference in patients with Behcet’s disease, patients with recurrent aphthous stomatitis, and control group.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Platelets play an important role in the pathogenesis of disorders associated with the local or systemic inflammation. Mean platelet volume (MPV) is a marker for platelet activation, and larger platelets are more activated. In this study, we aimed to investigate MPV values in patients with Behcet’s disease, patients with recurrent aphthous stomatitis, and controls. Methods: Patients with Behcet’s disease and patients with recur- rent aphthous stomatitis who presented to a dermatology outpa- tients clinic were enrolled in this study. Age, sex, MPV values, vitamin B12, and TSH were retrospectively recorded. Results: A total of 113 patients with recurrent aphthous stoma- titis, 87 patients with Behcet’s disease, and 71 healthy controls were enrolled in this study. Among them, 74 (65.5%) of the pa- tients with recurrent aphthous stomatitis were females, and 39 (35.5%) were males. Additionally, 50 (63.4%) of the patients with Behcet’s disease were females, and 37 (42.5%) were males. Finally, 45 (63.4%) of the controls were females, and 26 (36.6%) were males. There was no statistically significant difference in MPV values in patients with Behcet’s disease, patients with re- current aphthous stomatitis, and control group. Conclusion: MPV is a simple and useful parameter seen in routine complete blood count (CBC) laboratory tests. It is investigated as an inflammation marker. Although in some studies, MPV was high in patients with Behcet’s disease, in our study, we did not observe any statistically significant difference in patients with Behcet’s disease, patients with recurrent aphthous stomatitis, and control group.

Özet

Amaç: Trombositler lokal ve sistemik inflamasyon patogenezinde rol oynamaktadır. Ortalama trombosit hacmi (mean platelet vo- lume, MPV) trombosit aktivasyonun göstergesidir; büyük trom- bositlerin daha aktif olduğu düşünülmektedir. Çalışmamızda Behçet hastaları ve tekrarlayan oral aftı olan hastalarda MPVde- ğerlerini karşılaştırmayı amaçladık. Yöntemler: Çalışmamıza 2014 Ocak ile 2016 Kasım tarihle- ri arasında Bezmialem Vakıf Üniversitesi Tıp Fakültesi Deri ve Zührevi Hastalıkları polikliniklerine tekrarlayan oral aft ve Beh- çet hastalığı tanısı ile başvuran hastalar alındı. Hastaların yaş, cinsiyet, MPV değerleri, vitamin B12, TSH, paterji değerleri retrospektif olarak tarandı ve kaydedildi. Bulgular: Çalışmamıza tekrarlayan oral aftı (TOA) olan 113, Behçet hastalığı (BH) olan 87 ve kontrol grubu olarak 71 sağlık- lı kişi alındı. Tekrarlayan oral aftı olan hastaların 74’ü (%65,5) kadın, 39’u (%35,5) erkekti. Kontrol grubu, TOA ve BH grubu yaş ve cinsiyet açısından istatiksel olarak uyumluydu. BH’larının 50’si (%63,4) kadın, 37’si (%42,5) erkekti. Kontrol grubunun 45’i (%63,4) kadın, 26’sı (%36,6) erkekti. TOA’ı olan hastalar, BH’ları ve kontrol grubu arasında MPV değerleri açısından ista- tistiksel olarak anlamlı fark saptanmadı. Sonuç: MPV rutin kan tetkiklerinde bakılabilen basit ve kulla- nışlı bir parametredir. Ortalama trombosit hacmini göstermekte- dir. MPV inflamasyon belirteci olarak araştırılmıştır. Biz çalışma- mızda BH, TOA hastaları ve kontrol grubunda MPV değerleri açısından anlamlı fark saptamadık.

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Cite This Article

ÖZKAYA, D. B., KÜÇÜK, Ö. S., ONSUN, N. (2018). Comparing Mean Platelet Volume Values in Patients with Recurrent Aphthous Stomatitis and Patients with Behcet’s Disease. Bezmiâlem Science, Cilt: 6 - Sayı: 3, 196–199. https://ajindex.com/articles/153009

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