Journals / Medical Records / 2026 / Cilt: 5 Sayı: 2

Relationship between Arterial Stiffness and CHA2DS2-VASc Score in AF-related Stroke Patients

Fatih Akkaya(Department of Cardiology, Ordu University Faculty of Medicine)0000-0002-9016-4986
Yusuf Hoşoğlu(Department of Cardiology, Adiyaman University Training and Research Hospital)0000-0003-2440-9209
Mustafa İnç(Department of Cardiology, Aydin State Hospital)0000-0002-9492-6327
Vildan Altunayoglu Cakmak(Department of Neurology, Karadeniz Technical University School of Medicine)0000-0003-2828-2583
Abdulkadir Kırış(Department of Cardiology, Medicalpark Karadeniz Hospital)0000-0002-8209-6928
Pages
295–8
Publication Date
2023-05-15
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Calculation of CHA2DS2-VASc and monitoring of arterial stiffness in stroke-prone individuals may be stimulus for taking preventive measures from stroke in these patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Arterial stiffness is related with both atrial fibrillation (AF) and stroke.
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Key Findings & Data:The CHA2DS2-VASc score is used to assess stroke risk in patients with AF.
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Conclusion & Impact:Calculation of CHA2DS2-VASc and monitoring of arterial stiffness in stroke-prone individuals may be stimulus for taking preventive measures from stroke in these patients.
🔬Design:Klinik Araştırma
📍Scope:Comprehensive Sample
⚙️Variables:CHA2DS2-VASc · atrial fibrillation · pulse wave velocity

Abstract

Aim: Arterial stiffness is related with both atrial fibrillation (AF) and stroke. The CHA2DS2-VASc score is used to assess stroke risk in patients with AF. In this study, it was aimed to examine the relationship between arterial stiffness and CHA2DS2-VASc score in AF-related stroke patients. Material and Methods: Thirty stroke patients with paroxysmal AF participated in this research. Calculations of the patients' pre-stroke CHA2DS2-VASc scores were made. The SphygmoCor device was used to assess the Carotid-Femoral Pulse Wave Velocity (cfPWV), which served as a surrogate for arterial stiffness. It was determined whether or not there was a statistical connection between the CHA2DS2-VASc score and arterial stiffness. Results: The patients were seperated into groups based on their CHA2DS2-VASc scores prior to the stroke (group 1: score=0-1, group 2: score=≥2). The two groups' characteristics were comparable, except for age, BMI and systolic blood pressure. Patients with high CHA2DS2-VASc scores (group 2) demonstrated significantly greater cfPWV values than those with low scores (group 1). The CHA2DS2-VASc score and the cfPWV revealed a favourable association in the correlation study. Conclusion: The CHA2DS2-VASc score and cfPWV were substantially and linearly associated. Calculation of CHA2DS2-VASc and monitoring of arterial stiffness in stroke-prone individuals may be stimulus for taking preventive measures from stroke in these patients.

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Cite This Article

Akkaya, F., Hoşoğlu, Y., İnç, M., Cakmak, V. A., Kırış, A. (2023). Relationship between Arterial Stiffness and CHA2DS2-VASc Score in AF-related Stroke Patients. Medical Records, Cilt: 5 Sayı: 2, 295–8. https://doi.org/10.37990/medr.1207426

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References (17)

  1. Cecelja M, Chowienczyk P. Role of arterial stiffness in cardiovascular disease. JRSM Cardiovasc Dis. 2012;1:cvd.2012.012016.
  2. Laurent S, Cockcroft J, Van Bortel L, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J. 2006;27:2588-605.
  3. Ben-Shlomo Y, Spears M, Boustred C, et al. Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol. 2014;63:636-46.
  4. Van Bortel LM, Laurent S, Boutouyrie P, et al. Expert consensus document on the measurement of aortic stiffness in daily practice using carotid-femoral pulse wave velocity. J Hypertens. 2012;30:445-8.
  5. Chen Y, Shen F, Liu J, Yang GY. Arterial stiffness and stroke: de-stiffening strategy, a therapeutic target for stroke. Stroke Vasc Neurol. 2017;2:65-72.
  6. Lee HL, Kim JT, Lee JS, et al. CHA2DS2-VASc score in acute ischemic stroke with atrial fibrillation: results from the Clinical Research Collaboration for Stroke in Korea. Sci Rep. 2021;11:793.
  7. Gasecki D, Rojek A, Kwarciany M, et al. Aortic stiffness predicts functional outcome in patients after ischemic stroke. Stroke. 2012;43:543-4.
  8. Gasecki D, Coca A, Cunha P, et al. Blood pressure in acute ischemic stroke: challenges in trial interpretation and clinical management: position of the ESH Working Group on Hypertension and the Brain. J Hypertens. 2018;3:1212-21.
  9. Lage JGB, Bortolotto AL, Scanavacca MI, et al.Arterial stiffness and atrial fibrillation: A review. Clinics. 2022;77:100014.
  10. Hindricks G, Potpara T, Dagres N, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur Heart J. 2020;42:373-498.
  11. Koene RJ, Alraies MC, Norby FL, et al. Relation of the CHA(2)DS(2)-VASc Score to Risk of Thrombotic and Embolic Stroke in Community-Dwelling Individuals Without Atrial Fibrillation (From The Atherosclerosis Risk in Communities [ARIC] Study). Am J Cardiol. 2019;123:402-8.
  12. Williams B, Mancia G, Spiering W, et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension. J Hypertens. 2018;36:1953-2041.
  13. The Reference Values for Arterial Stiffness C. Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values’. Eur Heart J. 2010;31:2338-50.
  14. Kowalczyk K, Jabłoński B, Kwarciany M, et al. Changes of augmentation index early after ischaemic stroke predict functional outcome. Blood Pressure. 2020;29:327-35.
  15. Kwarciany M, Gąsecki D, et al. Acute hypertensive response in ischemic stroke is associated with increased aortic stiffness. Atherosclerosis. 2016;251:1-5.
  16. Chen LY, Foo DC, Wong RC, et al. Increased carotid intima-media thickness and arterial stiffness are associated with lone atrial fibrillation. Int J Cardiol. 2013;168:3132-4.
  17. Chung GE, Park HE, Lee H, Choi S-Y. Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score. Sci Rep. 2021;11:4955.