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Journals / Medical Records / 2026 / Cilt: 5 Sayı: 3

Relationship Between Chronic Spontaneous Urticaria and Fibromyalgia Syndrome

Sevgi Kulaklı(Giresun Üniversitesi Tıp Fakültesi)0000-0001-7886-1060
Işıl Deniz Oğuz(GİRESUN ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0001-8628-6107
İlker Fatih Sarı(GİRESUN ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-0127-6503
Halil Öğüt(HATAY MUSTAFA KEMAL ÜNİVERSİTESİ, TAYFUR ATA SÖKMEN TIP FAKÜLTESİ)0000-0002-0910-5728
Pages
638–43
Publication Date
2023-09-18
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Furthermore, the FMS prevalence was not affected by the duration and severity of urticaria; however, it was associated with decreased quality of life.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Autoimmunity, peripheral nerve dysfunction, and neurogenic inflammation are common mechanisms in chronic spontaneous urticaria (CSU) and fibromyalgia syndrome (FMS).
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Key Findings & Data:Material and Methods: Fifty-three patients with CSU and 49 controls were enrolled in this prospective, controlled, cross-sectional study.
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Conclusion & Impact:Furthermore, the FMS prevalence was not affected by the duration and severity of urticaria; however, it was associated with decreased quality of life.
🔬Design:Survey & Empirical Study
📍Scope:2016 Verileri
⚙️Variables:fibromiyalgia syndrome · chronic urticaria · quality of life

Abstract

Aim: Autoimmunity, peripheral nerve dysfunction, and neurogenic inflammation are common mechanisms in chronic spontaneous urticaria (CSU) and fibromyalgia syndrome (FMS). We aimed to detect the prevalence of FMS in patients with CSU and to determine whether this prevalence was affected by the severity of urticaria, and dermatology life quality. Material and Methods: Fifty-three patients with CSU and 49 controls were enrolled in this prospective, controlled, cross-sectional study. The severity of CSU was assessed using Urticaria Activity Scores (UAS), and Dermatology Life Quality Index (DLQI) scores were recorded. The 2016 fibromyalgia diagnostic criteria were used for the diagnosis of FMS, and FMS-related functional disability was assessed using the Fibromyalgia Impact Questionnaire (FIQ). Results: Fibromiyalgia prevalence and the FIQ scores were higher in the CSU group than in the control (p=0.033 and p=0.004, respectively). There was no statistically significant difference between the urticaria durations and UAS of CSU with and without FMS (p>0.05), but DLQI scores were statistically significantly higher in CSU with FMS (p=0.007). A statistically significant moderate positive correlation was present between DLQI and FIQ, Widespread Pain Index, and Symptom Severity Scale scores (r=0.500, r=0.408, r=0.469, r=0.507, respectively). Conclusions: The prevalence of FMS and the disability due to FMS was increased in CSU. Furthermore, the FMS prevalence was not affected by the duration and severity of urticaria; however, it was associated with decreased quality of life.

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Cite This Article

Kulaklı, S., Oğuz, I. D., Sarı, İ. F., Öğüt, H. (2023). Relationship Between Chronic Spontaneous Urticaria and Fibromyalgia Syndrome. Medical Records, Cilt: 5 Sayı: 3, 638–43. https://doi.org/10.37990/medr.1284145

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