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Journals / Medical Records / 2026 / Cilt: 7 Sayı: 1

Bacterial and Fungal Infections Among COVID-19 Patients in Intensive Care Unit

Deniz Gezer(MERSİN ŞEHİR EĞİTİM VE ARAŞTIRMA HASTANESİ)0000-0002-9036-0135
Sencer Yurtsever(MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-6690-119X
Seda Tezcan Ülger(MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-0823-3680
Pages
216–222
Publication Date
2025-01-15
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Evaluation of bacterial superinfections during the later waves of the pandemic may be critical, especially given the changes in the management of these patients, such as the routine use of corticosteroids and the raise of the different variants of the SARS-CoV-2.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Secondary infections caused by bacteria or fungi are dangerous because they increase death rates, particularly in patients with COVID-19 who are receiving intensive care.
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Key Findings & Data:In this study, hospital-associated secondary infections resulting from bacteria and fungi amid COVID-19 patients treated in intensive care units, as well as their distribution according to microbial agents, were investigated.
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Conclusion & Impact:Evaluation of bacterial superinfections during the later waves of the pandemic may be critical, especially given the changes in the management of these patients, such as the routine use of corticosteroids and the raise of the different variants of the SARS-CoV-2.
🔬Design:Klinik Araştırma
📍Scope:2021 Verileri
⚙️Variables:Corticosteroids · COVID-19 · intensive care unit

Abstract

Aim: Secondary infections caused by bacteria or fungi are dangerous because they increase death rates, particularly in patients with COVID-19 who are receiving intensive care. In this study, hospital-associated secondary infections resulting from bacteria and fungi amid COVID-19 patients treated in intensive care units, as well as their distribution according to microbial agents, were investigated. Material and Method: The study comprised 134 COVID-19 patients who were being treated in the Mersin City Hospital of the Ministry of Health intensive care unit between January 1, 2021, and April 30, 2021. The patients’ demographics and clinical records, as well as bacterial and fungal infections in the blood, urine and deep tracheal aspirate samples, were analyzed retrospectively. Results: The rate of secondary infection was found to be quite high in patients hospitalized in intensive care units for over 72 hours (91.4%). The majority of secondary infections were detected in blood samples (n=103, 15%). Secondary infection was detected in 61 (8.9%) deep tracheal aspirate specimens and 59 (8.5%) urine samples. The most common secondary infectious agents were Candida spp. (22.3%), Acinetobacter baumannii (16.8%). In addition, it was determined that ≥60 years and ≥3 days of mechanical ventilation independently increased the probability of developing secondary infection. Conclusion: Our findings are emphasized that the concern of secondary infection due to Candida spp., Acinetobacter baumanii and Stahylococcus epidermidis agents. Evaluation of bacterial superinfections during the later waves of the pandemic may be critical, especially given the changes in the management of these patients, such as the routine use of corticosteroids and the raise of the different variants of the SARS-CoV-2.

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Cite This Article

Gezer, D., Yurtsever, S., Ülger, S. T. (2025). Bacterial and Fungal Infections Among COVID-19 Patients in Intensive Care Unit. Medical Records, Cilt: 7 Sayı: 1, 216–222. https://doi.org/10.37990/medr.1527943

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