Journals / ANKEM Dergisi / 2013 / Cilt: 27 - Sayı: 2

Antibiotic Resistance of Streptococcus pneumoniae Strains Isolated from Clinical Specimens

Klinik örneklerden izole edilen Streptococcus pneumoniae suşlarının antibiyotik direnci

Pages
70–74
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Susceptibility rates of tested isolates were as follows; for penicillin, 82.5 % susceptible, 2.5 % intermediate, 15 % resistant; for erythromycin 81.6 % susceptible, 1.2 % intermediate, 17.2 % resistant; for clindamycin 85.6 % susceptible, 14.4 % resistant; for levofloxacin 94.3 % susceptible, 0.7 % intermediate, 5 % resistant; ofloxacin 89 % susceptible, 2 % intermediate and 9.0 % resistant and for vancomycin, all isolates were found susceptible.

📌 3 Key Takeaways

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Objective & Hypothesis:Streptococcus pneumoniae is one the most common agents that causes community-acquired pneumonia.
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Key Findings & Data:Penicillin is still the agent that commonly used in pneumoccal infections but because of the increasing rate of resistance other agents are used in treatment, too.
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Conclusion & Impact:Susceptibility rates of tested isolates were as follows; for penicillin, 82.5 % susceptible, 2.5 % intermediate, 15 % resistant; for erythromycin 81.6 % susceptible, 1.2 % intermediate, 17.2 % resistant; for clindamycin 85.6 % susceptible, 14.4 % resistant; for levofloxacin 94.3 % susceptible, 0.7 % intermediate, 5 % resistant; ofloxacin 89 % susceptible, 2 % intermediate and 9.0 % resistant and for vancomycin, all isolates were found susceptible.
🔬Design:Research Article
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

Streptococcus pneumoniae is one the most common agents that causes community-acquired pneumonia. Penicillin is still the agent that commonly used in pneumoccal infections but because of the increasing rate of resistance other agents are used in treatment, too. In this study we aimed to investigate the antimicrobial susceptibility of S.pneumoniae isolates in six years period. S.pneumoniae strains (n=328) that isolated from various clinical samples sent to the laboratory during January 2006 - December 2011 were evaluated retrospectively. S.pneumonaie isolates were identified by optochin disc method and Vitek2 Compact (Biomeriux, France) automatized system and antibiotic susceptibility was done by Kirby-Bauer disc diffusion method as recommended CLSI. Respiratory tract samples (n=147) were the most common clinical samples that S.pneumoniae were isolated. Susceptibility rates of tested isolates were as follows; for penicillin, 82.5 % susceptible, 2.5 % intermediate, 15 % resistant; for erythromycin 81.6 % susceptible, 1.2 % intermediate, 17.2 % resistant; for clindamycin 85.6 % susceptible, 14.4 % resistant; for levofloxacin 94.3 % susceptible, 0.7 % intermediate, 5 % resistant; ofloxacin 89 % susceptible, 2 % intermediate and 9.0 % resistant and for vancomycin, all isolates were found susceptible.

Özet

Streptococcus pneumoniae toplumdan kazanılmış pnömoniye en sık neden olan etkenlerden biridir. Pnömokok infeksiyonlarının tedavisinde penisilin en sık tercih edilen antimikrobik olmakla birlikte, artan direnç oranları nedeniyle farklı antimikrobikler de tedavide kullanılmaktadır. Bu çalışmada amacımız S.pneumoniae izolatlarının altı yıllık süre içindeki antibiyotik duyarlılıklarını incelemektir. Ocak 2006-Aralık 2011 tarihleri arasında laboratuvara gönderilen çeşitli klinik örneklerden üreyen 328 S.pneumoniae suşu değerlendirilmiştir. S.pneumoniae izolatlarının tanımlanması optokin disk testi ve Vitek2 Compact (Biomeriux, Fransa) otomatize sisteminde yapılmıştır. Antibiyotik duyarlılığı Vitek2 Compact sistemi ve bazı suşlarda Kirby-Bauer disk difüzyon yöntemiyle çalışılmıştır. S.pneumoniae izolatlarının en sık izole edildiği örnek türünün solunum yolu örnekleri olduğu görülmüştür (n=147). Antibiyotik duyarlılıkları ise; penisilin için % 82.5 duyarlı, % 2.5 orta duyarlı, % 15 dirençli; eritromisin için % 81.6 duyarlı, % 1.2 orta duyarlı, % 17.2 dirençli; klindamisin için % 85.6 duyarlı, % 14.4 dirençli; levofloksasin için % 94.3 duyarlı, % 0.7 orta duyarlı, % 5 dirençli; ofloksasin için % 89 duyarlı, % 2 orta duyarlı ve % 9.0 dirençli ve tüm izolatlar vankomisine duyarlı olarak saptanmıştır.

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Cite This Article

ÇAYCI, Y. T., YILMAZ, H., YANIK, K., KARADĞ, A., GÜNAYDIN, M. (2013). Antibiotic Resistance of Streptococcus pneumoniae Strains Isolated from Clinical Specimens. ANKEM Dergisi, Cilt: 27 - Sayı: 2, 70–74. https://ajindex.com/articles/152259

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