Structure determination of the new products ( 2-5 ) was established on the basis of IR, 1 H NMR, 13 C NMR , and mass spectrometry.
📌 3 Key Takeaways
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Objective & Hypothesis:The aim of this research is to synthesize and characterize of new cyclic members of cyclic aminobenzoquinones.
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Key Findings & Data:Mono amino substituted products; 2-chloro-5,6-dimethyl-3-(pyrrolidin-1-yl)-1,4-benzoquinone ( 2 ) , 2-chloro-5,6-dimethyl-3-(piperidin-1-yl)-1,4-benzoquinone ( 3 ) , 2-chloro-5,6-dimethyl-3-morpholino-1,4-benzoquinone ( 4 ), and 2 -chloro-5,6-dimethyl-3-thiomorpholino-1,4-benzoquinone ( 5 ) have been synthesized by a green methodology using water as solvent by means of nucleophilic substitution reactions between 2,3-dichloro-5,6-dimethyl-1,4-benzoquinone ( 1 ) and cyclic secondary amines.
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Conclusion & Impact:Structure determination of the new products ( 2-5 ) was established on the basis of IR, 1 H NMR, 13 C NMR , and mass spectrometry.
The aim of this research is to synthesize and characterize of new cyclic members of cyclic aminobenzoquinones. Mono amino substituted products; 2-chloro-5,6-dimethyl-3-(pyrrolidin-1-yl)-1,4-benzoquinone ( 2 ) , 2-chloro-5,6-dimethyl-3-(piperidin-1-yl)-1,4-benzoquinone ( 3 ) , 2-chloro-5,6-dimethyl-3-morpholino-1,4-benzoquinone ( 4 ), and 2 -chloro-5,6-dimethyl-3-thiomorpholino-1,4-benzoquinone ( 5 ) have been synthesized by a green methodology using water as solvent by means of nucleophilic substitution reactions between 2,3-dichloro-5,6-dimethyl-1,4-benzoquinone ( 1 ) and cyclic secondary amines. Structure determination of the new products ( 2-5 ) was established on the basis of IR, 1 H NMR, 13 C NMR , and mass spectrometry.
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