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Journals / Journal of Surgery and Medicine / 2018 / Cilt: 2 Sayı: 3

Kounis syndrome as a result of anaphylactic reaction to diclofenac sodium: A case report

Diklofenak sodyum kullanımı sonrası anafilaktik reaksiyon sonucu gelişen Kounis sendromu: Olgu sunumu

Abdullah İbrahim(Haydarpasa Numune Training and Research Hospital)
Şahin Çolak(Haydarpasa Numune Training and Research Hospital)
Mehmet Özgür Erdoğan(Haydarpasa Numune Training and Research Hospital)
Mustafa Ahmet Afacan(Haydarpasa Numune Training and Research Hospital)
Ayhan Sarıtaş(Duzce University School of Medicine Department of Emergency Medicine)
Hayati Kandiş(Duzce University School of Medicine Department of Emergency Medicine)
Pages
337–338
Publication Date
2018-09-01
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present a case of a patient who developed Kounis syndrome as a result of anaphylactic reaction to Voltaren (Diclofenac sodium) which is one of the drugs widely used in the emergency departments as intramuscular pain killer.

📌 3 Key Takeaways

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Objective & Hypothesis:Kounis syndrome refers to acute coronary syndromes of varying degrees (myocardial ischaemia to infarction) induced by mast cell activation as a result of allergic and anaphylactic reactions.
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Key Findings & Data:Following subclinical, acute or chronic allergic reactions, it has a clinical spectrum ranging from chest pain to ST segment elevated myocardial infarction.
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Conclusion & Impact:We present a case of a patient who developed Kounis syndrome as a result of anaphylactic reaction to Voltaren (Diclofenac sodium) which is one of the drugs widely used in the emergency departments as intramuscular pain killer.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Kounis sendromu · Diklofenak sodyum · Aşırı duyarlılık

Abstract

Kounis syndrome refers to acute coronary syndromes of varying degrees (myocardial ischaemia to infarction) induced by mast cell activation as a result of allergic and anaphylactic reactions. Following subclinical, acute or chronic allergic reactions, it has a clinical spectrum ranging from chest pain to ST segment elevated myocardial infarction. The trigger of the allergic reaction can be drugs, food, environmental factors (insect bite, bee sting, pollen, latex contact). We present a case of a patient who developed Kounis syndrome as a result of anaphylactic reaction to Voltaren (Diclofenac sodium) which is one of the drugs widely used in the emergency departments as intramuscular pain killer.

Özet

Kounis sendromu mast hücrelerinin etkinleşmesi ile seyreden alerji, hipersensitivite, anaflaksi veya anaflaktoid reaksiyonlarla ilişkili olarak akut koroner sendromun değişik derecelerini ifade eder. Subklinik olarak akut veya kronik alerjik reaksiyona eşlik eden ve göğüs ağrısından başlayıp ST elavasyonlu miyokard enfarktüsü kadar uzanan bir klinik spektruma sahiptir. İlaçlar, yiyecekler, çevresel etkenler (böcek ısırması, arı sokması, polenler, lateks teması gibi) alerjik reaksiyonu tetikleyen neden olabilir. Burada, acil servislerde yaygın olarak kullanılan Voltaren’e (Diklofenak sodyum) bağlı gelişen anafilaktik reaksiyonu olan bir Kounis sendrom vakasını sunuyoruz.

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Cite This Article

İbrahim, A., Çolak, Ş., Erdoğan, M. Ö., Afacan, M. A., Sarıtaş, A., Kandiş, H. (2018). Kounis syndrome as a result of anaphylactic reaction to diclofenac sodium: A case report. Journal of Surgery and Medicine, Cilt: 2 Sayı: 3, 337–338. https://doi.org/10.28982/josam.402775

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References (10)

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