Journals / Journal of Surgery and Medicine / 2019 / Cilt: 3 Sayı: 12

Complete scintigraphic resolution of a bone metastasis after androgen-deprivation therapy

Derya Çayır(ANKARA DIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİ)0000-0002-7756-3210
Mehmet Bozkurt(ANKARA DIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİ)0000-0002-8325-5249
Salih Sinan Gültekin(ANKARA DIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİ)0000-0003-2458-3530
Aynur Turan(ANKARA DIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİ)0000-0001-6654-3129
Pages
898–899
Publication Date
2019-12-03
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here we present a rare case of prostate cancer with radiologically undetectable bone metastasis evident on scintigraphy that has disappeared after 18 months of ADT.

📌 3 Key Takeaways

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Objective & Hypothesis:99mTc-methylene diphosphonate (MDP) whole body bone scintigraphy is a frequently used imaging method for the evaluation of the bone metastases of prostate cancer.
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Key Findings & Data:Nuclear medicine imaging modalities are very valuable in terms of functional assessment and treatment response assessment of the malign lesions that cannot be detected by anatomic imaging methods.
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Conclusion & Impact:Here we present a rare case of prostate cancer with radiologically undetectable bone metastasis evident on scintigraphy that has disappeared after 18 months of ADT.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Tüm vücut görüntüleme · Prostat kanseri · Metastaz

Abstract

99mTc-methylene diphosphonate (MDP) whole body bone scintigraphy is a frequently used imaging method for the evaluation of the bone metastases of prostate cancer. Nuclear medicine imaging modalities are very valuable in terms of functional assessment and treatment response assessment of the malign lesions that cannot be detected by anatomic imaging methods. However, it is known that some scintigraphic studies may have a relatively limited role in defining resolution and anatomical details of the lesion, compared to some radiological imaging modalities. Androgen-deprivation therapy (ADT) alone is rarely effective for the treatment of bone metastases, on that account combined systemic therapies are often preferred. Here we present a rare case of prostate cancer with radiologically undetectable bone metastasis evident on scintigraphy that has disappeared after 18 months of ADT.

Özet

99mTc-metilen difosfonat (MDP) tüm vücut kemik sintigrafisi prostat kanserinin kemik metastazlarını değerlendirmede sıklıkla kullanılmaktadır. Anatomik görüntüleme yöntemleri ile saptanamayan malign lezyonların fonksiyonel olarak izlenebilmesi ve tedaviye yanıtının değerlendirilebilmesi açısından nükleer tıp tetkikleri çok değerlidir. Bununla birlikte sintigrafik yöntemlerin rezolüsyon ve anatomik detayları belirlemede bazı radyolojik tetkiklere göre sınırlı olabildiği bilinmektedir. Kemik metastazlarının tedavisinde sıklıkla kombine sistemik tedaviler tercih edilmekte olup, androjen-deprivasyon tedavisi (ADT) tek başına nadiren etkilidir. Burada bilgisayarlı tomografi ile saptanamayan, 18 ay ADT ile regrese olan kemik metastazlı nadir prostat kanserli bir olguyu sunuyoruz.

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Cite This Article

Çayır, D., Bozkurt, M., Turan, A. (2019). Complete scintigraphic resolution of a bone metastasis after androgen-deprivation therapy. Journal of Surgery and Medicine, Cilt: 3 Sayı: 12, 898–899. https://doi.org/10.28982/josam.598062

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