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Journals / Journal of Surgery and Medicine / 2026 / Cilt: 5 Sayı: 4

Retrospective assessment of fungal pathogens isolated from various clinical samples in a tertiary care hospital in Turkey: A cross-sectional study

Meryem Çolak(KARABÜK ÜNİVERSİTESİ, TIP FAKÜLTESİ, TEMEL TIP BİLİMLERİ BÖLÜMÜ, TIBBİ MİKROBİYOLOJİ ANABİLİM DALI)0000-0001-9876-935X
Nergis Aşgın(KARABÜK ÜNİVERSİTESİ, TIP FAKÜLTESİ, TEMEL TIP BİLİMLERİ BÖLÜMÜ, TIBBİ MİKROBİYOLOJİ ANABİLİM DALI)0000-0001-9739-5675
Pages
362–366
Publication Date
2021-04-01
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, each country should figure out its local fungal profile and update its antifungal treatment protocols accordingly.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/Aim: Fungal infections are an emerging health problem worldwide and can be caused by a broad variety of fungal pathogens.
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Key Findings & Data:Methods: A total of 996 clinical samples obtained from 803 patients who visited Karabuk University Training and Research Hospital microbiology laboratory between January 2019-December 2020 were included in this study.
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Conclusion & Impact:Therefore, each country should figure out its local fungal profile and update its antifungal treatment protocols accordingly.
🔬Design:Araştırma Makalesi
📍Scope:2019 Verileri
⚙️Variables:Fungal pathogen · Candida albicans · Candida tropicalis

Abstract

Background/Aim: Fungal infections are an emerging health problem worldwide and can be caused by a broad variety of fungal pathogens. This study aimed to retrospectively determine and evaluate the fungal pathogens isolated from various clinical samples in our laboratory. Methods: A total of 996 clinical samples obtained from 803 patients who visited Karabuk University Training and Research Hospital microbiology laboratory between January 2019-December 2020 were included in this study. The BD-Phoenix 100 automated microbiology system was used for the identification of strains. Results: Among 803 patients, 52.4% were female and 47.5% were male. The median age of the patients was 76 (0-99) years. Urine (49%) and blood (27.6%) samples were evaluated the most. The most common fungal pathogen was Candida albicans (48.7%), followed by Candida tropicalis (16.5%), Candida parapsilosis (10.6%), Candida glabrata (9%), Saccharomyces cerevisiae (5.7%), and Trichosporon species (3.1%). While more than 90% of fungal strains were isolated from the inpatients, 9% were isolated from the outpatients (p<0.05). Among all, 69.4% of strains were isolated from the intensive care units, followed by internal medicine (5.5%), palliative care (5%), urology (3.6%), and orthopedics and traumatology clinics (2.1%). Conclusion: Although C. albicans is still the most common fungal pathogen, the incidences of non-albicans candida and other fungi are increasing worldwide. Therefore, each country should figure out its local fungal profile and update its antifungal treatment protocols accordingly.

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Cite This Article

Çolak, M., Aşgın, N. (2021). Retrospective assessment of fungal pathogens isolated from various clinical samples in a tertiary care hospital in Turkey: A cross-sectional study. Journal of Surgery and Medicine, Cilt: 5 Sayı: 4, 362–366. https://doi.org/10.28982/josam.910783

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