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Journals / Journal of Surgery and Medicine / 2026 / Cilt: 5 Sayı: 9

Nano-based ceramic surgical blade accelerates wound healing

Fatih Ada(SİVAS CUMHURİYET ÜNİVERSİTESİ)0000-0002-6953-5906
Erkan Gümüş(ADNAN MENDERES UNIVERSITY)0000-0001-6432-7457
Ferit Kasımzade(Ankara Şehir Hastanesi)0000-0003-3646-3181
Pages
924–927
Publication Date
2021-09-01
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The use of nano-based zirconia surgical blade should be kept in mind in patient groups with wound healing problems.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/Aim: Many factors affect the results of a surgical operation, one of which is the harmony of the materials used during surgery with the tissue.
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Key Findings & Data:Methods: The study was conducted after approval was granted by the Sivas Cumhuriyet University Animal Experiments Local Ethics Committee with the decision number 65202830-050.04.04-33.
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Conclusion & Impact:The use of nano-based zirconia surgical blade should be kept in mind in patient groups with wound healing problems.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Ceramic · Healing · Histological

Abstract

Background/Aim: Many factors affect the results of a surgical operation, one of which is the harmony of the materials used during surgery with the tissue. Zirconia is a material with antimicrobial properties, high surface sensitivity and robustness. This study was conducted to observe the acute and subacute effects of the nano-based zirconia surgical blade on living tissue. Methods: The study was conducted after approval was granted by the Sivas Cumhuriyet University Animal Experiments Local Ethics Committee with the decision number 65202830-050.04.04-33. A total of 16 rats were used in the study. Eight were incised with classic steel surgical blade and eight, with nano-based zirconia surgical blade. A total of 4 incisions were performed to each rat and the incisions were closed with 3.0 polypropylene suture. Tissue samples were obtained from the incisions on day 0, 3, 7 and 21, and examined histologically. Results: The epidermis layer thickness on days 7 and 21 (P=0.030, P=0.025), the dermis layer thickness on days 3 and 7 (P=0.035, P=0.030), muscle layer thickness on days 7 and 21 (P=0.030, P=0.025) were significantly increased and inflammatory cells were significantly less on days 3, 7 and 21 (P=0.030, P=0.020, P=0.025) in the nano-ceramic surgical blade compared to the other group. Collagen tissue density was significantly higher in favor of the nano-ceramic blade on the 3rd and 7th days (P=0.025, P=0.020). Conclusion: Nano-based zirconia surgical blade has been shown to have positive effects on wound healing. The use of nano-based zirconia surgical blade should be kept in mind in patient groups with wound healing problems.

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Cite This Article

Ada, F., Gümüş, E., Kasımzade, F. (2021). Nano-based ceramic surgical blade accelerates wound healing. Journal of Surgery and Medicine, Cilt: 5 Sayı: 9, 924–927. https://doi.org/10.28982/josam.857885

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References (20)

  1. Parsak CK, Sakman G, Çelik, Ü. Yara iyileşmesi, yara bakımı ve komplikasyonları. Arşiv Kaynak Tarama Dergisi. 2007;16(2):145-59.
  2. Mftah A, Alhassan FH, Al-Qubaisi MS, El Zowalaty ME, Webster TJ, Sh-eldin M, et al. Physicochemical properties, cytotoxicity, and antimicrobial activity of sulphated zirconia nanoparticles. International Journal of Nanomedicine. 2015;10: 765.
  3. Kuai JC, Zhang FH, Liu YZ. ELID Grinding Technology of Nano-Material Cutting Tool. In Applied Mechanics and Materials. 2012;155:960-4.
  4. Kuai JC, Zhang FH, Liu YZ. ELID Grinding Technology of Nano-Ceramic Scalpel. In Advanced Materials Research. 2012;468:1560-3.
  5. Strong AL, Bowles AC, MacCrimmon CP, Frazier TP, Lee SJ, Wu X, et al. Adipose stromal cells repair pressure ulcers in both young and elderly mice: potential role of adipogenesis in skin repair. Stem Cells Translational Medicine. 2015;4(6):632-42.
  6. Barbul A. Wound healing. Schwartz’s Principles of Surgery. Mc Graw Hill Eight edition. 2005;223.
  7. Sherris DA, Kern EB. The Wound. In Basic Surgical Skills, Mayo Foundation for medical Education and research, Rochester, 1999:8-12.
  8. Pakyari M, Farokhi A, Jalili RB, Kilani RT, Brown E, Ghahary, A. Local Expression of Indoleamine 2, 3, Dioxygenase Prolongs Allogenic Skin Graft Take in a Mouse Model. Advances in Wound Care. 2018;8(2):58-70.
  9. Özpolat B, Gürpınar Aylin Ö, Ayva Şebnem E, Gazyağcı S, Niyaz M. The effect of basic fibroblast growth factor and adipose tissue-derived mesenchymal stem cells on wound healing, epithelization and angiogenesis in a tracheal resection and end-to-end anastomosis rat model. Turkish Journal of Thoracic and Cardiovascular Surgery. 2013;21:1010-9.
  10. Gupta A, Kumar P. Assessment of the histological state of the healing wound. Plastic and Aesthetic Research. 2015;2(5):239.
  11. Durgun M, Durgun Ögücü S, Özakpınar Rıfat H, Eryılmaz Tolga A, Öktem Fatih H, İnözü E, et al. Approach to of infected sternotomy wounds in the management of mediastinitis. Turkish Journal of Thoracic and Cardiovascular Surgery. 2012;20:820-5.
  12. Ryu SW, Lee SH, Yoon HJ. A comparative histological and immunohistochemical study of wound healing following incision with a scalpel, CO2 laser or Er, Cr: YSGG laser in the Guinea pig oral mucosa. Acta Odontologica Scandinavica. 2012;70(6):448-54.
  13. Carreira LM, Azevedo P. Comparison of the Influence of CO2-laser and Scalpel Skin Incisions on the Surgical Wound Healing Process. ARC Journal of Anesthesiology. 2016;1(3):1-8.
  14. Jawad MM, Alam MK, AbdulQader ST, Al-Azzawi LM, Husein A, Mahmood AS. Histological evaluation of incision healing response made by metallic scalpel on rabbits skin: preliminary study. International Medical Journal. 2013;20(4):496-8.
  15. Demir T, Kara C, Özbek E, Kalkan Y. Evaluation of neodymium-doped yttrium aluminium garnet laser, scalpel incision wounds, and low-level laser therapy for wound healing in rabbit oral mucosa: a pilot study. Photomedicine and laser surgery. 2010;28(1):31-7.
  16. Tuncer I, Özçakır-Tomruk C, Şencift K, Çöloğlu S. Comparison of conventional surgery and CO2 laser on intraoral soft tissue pathologies and evaluation of the collateral thermal damage. Photomedicine and laser surgery. 2010;28(1):75-9.
  17. Kara C, Süleyman H, Tezel A, Orbak R, Cadirci E, Polat B, Kara I. Evaluation of pain levels after Nd: YAG laser and scalpel incisions: an experimental study in rats. Photomedicine and laser surgery. 2010;28(5):635-8.
  18. Pearce EC, Hall JE, Boyd KL, Rousseau B, Ries WR. The Ophthalmology Microscalpel versus Standard Scalpels and Wound Healing in a Rat Model. Otolaryngology-Head and Neck Surgery. 2014;151(3):424-30.
  19. Tsai PH, Lin YZ, Li JB, Jian SR, Jang JSC, Li C, et al. Sharpness improvement of surgical blade by means of ZrCuAlAgSi metallic glass and metallic glass thin film coating. Intermetallics. 2012;31:127-31.
  20. Kelley DB, Abt AB. Uniform Tissue Sections Cut with a Double-Bladed Scalpel. Journal of Histotechnology.2013;16(4):363-4.