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Journals / Causapedia / 2016 / Cilt: 5 - Sayı: 2

Konservatif Tedavi Edilen Endometriyum Karsinomu Sonrası Spontan Gebelik Kadın Hastalıkları ve Doğum

Spontaneous Pregnancy After Conservatively Treated Endometrial Adenocarcinoma

AYŞE YASEMİN KARAGEYİM KARŞIDAĞ
ESRA ESİM BÜYÜKBAYRAK
Meltem PİRİMOĞLU
Journal
Causapedia
Pages
92–95
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We conclude that conservative treatment of early stage endometrial adenocarcinoma in young women wishing fertility is an option in carefully selected cases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 26 year old women complaining of primary infertility has applied to our clinic.
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Key Findings & Data:During infertility workup, her endometrium was irregular and thick so endometrial sampling was performed and ‘well differentiated endometrial adenocarcinoma, Grade 1’ was detected.
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Conclusion & Impact:We conclude that conservative treatment of early stage endometrial adenocarcinoma in young women wishing fertility is an option in carefully selected cases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 26 year old women complaining of primary infertility has applied to our clinic. During infertility workup, her endometrium was irregular and thick so endometrial sampling was performed and ‘well differentiated endometrial adenocarcinoma, Grade 1’ was detected. Magnetic resonance imaging (MRI) showed 36x19mm mass in endometrial cavity. Positron Emission Tomography (PET) was normal except uterine lesion. Full curettage was performed and after curettage, we confirmed that there was no detectable endometrial mass or myometrial invasion or cervical involvement by MRI imaging. After counseling, the patient wished to retain her ability to conceive, so high dose progestin therapy was recommended. After megestrol acetate usage for 12 months, we found atrophic endometrium by ultrasound examination, and this was confirmed as atrophic endometrium by histological examination. Then, megestrol acetate treatment was stopped and the patient resumed her menses. She was scheduled for a control visit but she turned out to be pregnant. Then she received routine obstetrical care and delivered by Cesarean section at 39 weeks in gestational periods. We conclude that conservative treatment of early stage endometrial adenocarcinoma in young women wishing fertility is an option in carefully selected cases.

Özet

Yirmi altı yaşındaki hasta kliniğimize primer infertilitetanısı ile başvurdu. Infertilite tetkikleri sırasında kalın vedüzensiz endometriyum saptanması üzerine yapılanendometriyal örneklemede 'iyi diferansiye endometriyaladenokarsinom. Grade 1' saptandı. Manyetik rezonansincelemede (MR) endometriyal kavitede 36X19mm kitleizlendi. Pozitron Emisyon Tomografi (PET), uterinlezyon dışında normal olarak saptandı. Full küretajuygulandı ve işlem sonrası MR ile rezidü endometriyallezyon, myometriyal ve servikal invazyon izlenmedi.Hasta ile görüşüldükten sonra, hastanın gebelik isteğinedeni ile yüksek doz gestagen tedavisi planlandı.Megestrol asetatın 12 ay kullanımından sonra ultrasondaatrofik endometriyum izlendi ve histolojik olarak ta tanıdoğrulandı. Megestrol asetat kesildi ve hasta adetgörmeye başladı. Kontrole çağrılan hasta spontan gebekalarak başvurdu. Rutin obstetrik izleme alınan hasta,39. haftada sezaryen ile doğum yaptı. Fertilite isteği olanerken evre endometriyum adenokarsinomu saptanangenç kadınlarda konservatif tedavi bir seçenek olaraksunulmalıdır

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Cite This Article

KARŞIDAĞ, A. Y. K., BÜYÜKBAYRAK, E. E., PİRİMOĞLU, M. (2016). Konservatif Tedavi Edilen Endometriyum Karsinomu Sonrası Spontan Gebelik Kadın Hastalıkları ve Doğum. Causapedia, Cilt: 5 - Sayı: 2, 92–95. https://ajindex.com/articles/150979

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