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Journals / Journal of Health Sciences and Medicine / 2026 / Volume: 5 Issue: 4

Methanol poisoning in the emergency department: a retrospective study

Guner Yurtsever(İZMİR ATATURK RESEARCH AND TRAİNİNG HOSPİTAL)0000-0002-6803-1239
Cüneyt Arıkan(İZMİR ATATURK RESEARCH AND TRAİNİNG HOSPİTAL)0000-0001-6823-5357
Hüseyin Acar(İZMİR ATATURK RESEARCH AND TRAİNİNG HOSPİTAL)0000-0002-1905-7133
Omay Sorgun(Izmir Ödemiş State Hospital)0000-0002-0376-7173
Ejder Saylav Bora(İZMİR ATATURK RESEARCH AND TRAİNİNG HOSPİTAL)0000-0002-2448-2337
Pages
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Publication Date
2022-07-20
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no difference in mortality between patients treated with ethanol and fomepizole.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Massive methanol poisonings have occurred in the past decades, resulting in a large number of deaths.
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Key Findings & Data:In this study, our aim is to retrospectively analyze methanol poisoning cases admitted to the emergency department between 2019-2021, to evaluate their demographic characteristics, causes of poisoning, clinical and laboratory findings, treatments applied and mortality, and to contribute to the poisoning data of our country.
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Conclusion & Impact:There was no difference in mortality between patients treated with ethanol and fomepizole.
🔬Design:Review & Systematic Survey
📍Scope:2019-2021 Verileri
⚙️Variables:methanol intoxication · mortality · emergency department

Abstract

Aim: Massive methanol poisonings have occurred in the past decades, resulting in a large number of deaths. In this study, our aim is to retrospectively analyze methanol poisoning cases admitted to the emergency department between 2019-2021, to evaluate their demographic characteristics, causes of poisoning, clinical and laboratory findings, treatments applied and mortality, and to contribute to the poisoning data of our country. Material and Method: The cases of methanol poisoning who applied to the emergency department in a 3-year period were analyzed retrospectively. Medical files of patients aged 18 years and older were reviewed. Patients diagnosed with 'methanol poisoning' as a result of the examination were included in the study. Results: A total of 59 patients were included in the study. 88% (n=52) of the patients with a mean age of 53±10 were male. The presence of neurological symptoms and GCS were associated with mortality among the symptoms of patients presenting to the emergency department (p=0.017, p<0.001, respectively), it was seen that low pH and NaHCO3, and high lactate, serum sodium and anion gap were associated with mortality (p<0.001, p=0.003, p<0.001, p=0.022, respectively, p=0.001) Conclusion: Methanol poisoning is a disease with high mortality despite the improved treatment possibilities. Lactate level was found to be an independent factor for mortality, and increased lactate levels are associated with poor clinical outcome. There was no difference in mortality between patients treated with ethanol and fomepizole.

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Cite This Article

Yurtsever, G., Arıkan, C., Acar, H., Sorgun, O., Bora, E. S. (2022). Methanol poisoning in the emergency department: a retrospective study. Journal of Health Sciences and Medicine, Volume: 5 Issue: 4. https://doi.org/10.32322/jhsm.1095045

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