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Journals / Journal of Health Sciences and Medicine / 2026 / Volume: 8 Issue: 2

Ultrasonographic evaluation of Caval Aortic Index in gestational and pregestational diabetes: a predictor of perinatal outcomes?

Gestasyonel ve pregestasyonel diyabette Caval Aort İndeksinin ultrasonografik değerlendirmesi: perinatal sonuçları öngörebilir mi?

Gülşan Karabay(ANKARA ETLİK ŞEHİR HASTANESİ)0000-0003-2567-2850
Zeynep Şeyhanlı(Ankara Etlik Şehir Hastanesi)0000-0003-3924-3723
Ahmet Arif Filiz(Ankara Etlik Şehir Hastanesi)0000-0002-6137-0270
Betül Tokgöz Çakır(Ankara Etlik Şehir Hastanesi)0000-0003-0202-4981
Gizem Aktemur(Ankara Etlik Şehir Hastanesi)0000-0001-6824-881X
Sadun Sucu(Ankara Etlik Şehir Hastanesi)0000-0003-3758-0136
Nazan Vanlı Tonyalı(Ankara Etlik Şehir Hastanesi)0000-0002-7284-6887
Umut Karabay(Gülhane Eğitim Araştırma Hastanesi)0000-0002-9632-360X
Şevki Çelen(Ankara Etlik Şehir Hastanesi)0000-0001-7033-3474
Zehra Vural Yılmaz(Ankara Etlik Şehir Hastanesi)0000-0002-8719-1879
Pages
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Publication Date
2025-03-21
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

While the Caval Aortic Index provides limited prognostic utility, integrating these measurements into comprehensive models may enhance perinatal risk assessment.

📌 3 Key Takeaways

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Objective & Hypothesis:Aims: Diabetes mellitus (DM), including gestational (GDM) and pregestational diabetes (pre-GDM), adversely affects maternal and fetal outcomes due to hyperglycemia and vascular changes.
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Key Findings & Data:Methods: This prospective case-control study included 120 DM patients and 100 controls.
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Conclusion & Impact:While the Caval Aortic Index provides limited prognostic utility, integrating these measurements into comprehensive models may enhance perinatal risk assessment.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Gestational diabetes · pregestational diabetes · Caval Aortic Index

Abstract

Aims: Diabetes mellitus (DM), including gestational (GDM) and pregestational diabetes (pre-GDM), adversely affects maternal and fetal outcomes due to hyperglycemia and vascular changes. The Caval Aortic Index, a non-invasive measure of blood volume, could provide insights into these complications. In our study, we aimed to determine the functional changes in inferior vena cava (IVC) and aorta (Ao) diameters as well as the importance of caval aortic index in predicting perinatal outcomes in diabetic pregnant women. Methods: This prospective case-control study included 120 DM patients and 100 controls. DM patients were divided into pre-GDM, diet-regulated GDM, and insulin-regulated GDM groups. Ultrasound measurements of inferior vena cava and aortic diameters were performed, alongside Doppler evaluations. Statistical analyses were conducted to assess the association of these parameters with adverse perinatal outcomes. Results: Although the IVC and aortic diameters of the pregnant women with DM were higher compared to the control group and a statistically significant difference (p 3.81 mm (AUC: 0.674). Conclusion: Ultrasonographic IVC and aortic diameters reflect vascular adaptations in diabetic pregnancies but lack predictive value for adverse outcomes. While the Caval Aortic Index provides limited prognostic utility, integrating these measurements into comprehensive models may enhance perinatal risk assessment.

Özet

Amaç: Diabetes mellitus (DM), gebelik diyabeti (GDM) ve gebelik öncesi diyabeti (pre-GDM) içermekle beraber hiperglisemi ve vasküler değişiklikler nedeniyle maternal ve fetal sonuçları olumsuz etkileyebilir. Kaval aortik indeks, dolaşımdaki kan hacmini değerlendiren non-invaziv bir parametre olup, bu komplikasyonlar ile ilişkilendirilebilir. Biz de çalışmamızda diyabetli gebelerde inferior vena kava (IVC) ve aort (Ao) çaplarındaki fonksiyonel değişikliklerin yanı sıra kaval aort indeksinin perinatal sonuçları tahmin etmedeki önemini belirlemeyi amaçladık. Yöntemler: Bu prospektif vaka-kontrol çalışmasına 120 DM olan gebe ve 100 sağlıklı kontrol gebesi dahil edilmiştir. DM olan gebeler; pre-GDM, diyetle düzenlenen ve insülinle düzenlenen GDM olarak üç gruba ayrılmıştır. Ultrasonografi ile inferior vena kava ve aort çapları ölçülmüş ve Doppler değerlendirmeleri yapılmıştır. Bu parametrelerin olumsuz perinatal sonuçlarla ilişkisi istatistiksel analizlerle değerlendirilmiştir. Bulgular: DM olan gebelerin IVC ve aort çapları, kontrol grubuna kıyasla daha yüksek olup gruplar arasında istatistiksel olarak anlamlı fark (p 3.81 mm kesim noktası ile AUC: 0.674 olarak hesaplanmıştır. Sonuç: Ultrasonografik IVC ve aort çapları, diyabetik gebeliklerde vasküler adaptasyonları yansıtabilir ancak olumsuz perinatal sonuçları öngörmede sınırlı değere sahiptir. Kaval aortik indeksin prognostik değeri düşük olmakla birlikte, bu ölçümlerin kapsamlı risk değerlendirme modellerine entegre edilmesi, perinatal risk öngörüsünü artırabilir.

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Cite This Article

Karabay, G., Şeyhanlı, Z., Filiz, A. A., Çakır, B. T., Aktemur, G., Sucu, S., Tonyalı, N. V., Karabay, U., Çelen, Ş., Yılmaz, Z. V. (2025). Ultrasonographic evaluation of Caval Aortic Index in gestational and pregestational diabetes: a predictor of perinatal outcomes?. Journal of Health Sciences and Medicine, Volume: 8 Issue: 2. https://doi.org/10.32322/jhsm.1616423

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