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Journals / Journal of Health Sciences and Medicine / 2026 / Volume: 8 Issue: 5

Efficacy and safety of intravaginal gas ozone therapy in the treatment of bacterial vaginosis

Bakteriyel vajinozis tedavisinde intravajinal gaz ozon tedavisinin etkinliği ve güvenliği

Savaş Özgür Ağlamış(DR Özgür Ağlamış Clinic)0000-0003-1803-106X
Seval Yılmaz Ergani(4 Department of Perinatology, Etlik City Hospital, Ankara, Turkey)0000-0002-7017-8854
Eda Adeviye Şahin(Dr Eda Sahin private clinic)0000-0003-4004-8167
Hanifi Şahin(İstanbul Health and Technology University,)
Turan Şahin(Dr ilhan Varank training research hospital)0000-0003-1616-9735
Pages
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Publication Date
2025-09-16
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further investigation with a larger number of patients should be conducted to confirm our data.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aims: The aim of this study is to share our experiences and results with our intravaginal gas ozone technique in the treatment of bacterial vaginosis (BV) by retrospective data analysis.
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Key Findings & Data:Methods: Salutem plus brand medical ozone device, 60 gamma 200 cc gas ozone was administered intravaginally through 50 cc syringes with the help of a nasogastric catheter to 102 patients diagnosed with BV using Amsel criteria.
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Conclusion & Impact:Further investigation with a larger number of patients should be conducted to confirm our data.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Bacterial vaginosis · intravaginal · ozone therapy

Abstract

Aims: The aim of this study is to share our experiences and results with our intravaginal gas ozone technique in the treatment of bacterial vaginosis (BV) by retrospective data analysis. Methods: Salutem plus brand medical ozone device, 60 gamma 200 cc gas ozone was administered intravaginally through 50 cc syringes with the help of a nasogastric catheter to 102 patients diagnosed with BV using Amsel criteria. Patients whose hemogram parameters were checked before and after the procedure were called for 1st, 3rd, 6th, 9th and 12th month clinical controls in terms of recurrence, and the examination findings and digital data of these patients were analyzed retrospectively in terms of treatment, complications and recurrence. Results: No life-threatening complications were encountered. Minor adverse effects were observed and resolved spontaneously in a short time without the need for any treatment. Recurrence rates were observed to be lower than in classical regimen treatments. Additionally, no more than 2 recurrences were observed during 1-year follow-up. Conclusion: Our study is the first example of the literature in terms of evaluation of treatment, recurrence and complications of intravaginal gas ozone therapy in the treatment of bacterial vaginosis. These finding suggest that intravaginal gas ozone therapy, which is considered a safe form of treatment, will become more widespread in the future and the number and frequency of its application will increase even more. Further investigation with a larger number of patients should be conducted to confirm our data.

Özet

Özet Amaçlar: Bu çalışmanın amacı, bakteriyel vajinozis (BV) tedavisinde intravajinal gaz ozon tekniğimizle ilgili deneyimlerimizi ve sonuçlarımızı retrospektif veri analiziyle paylaşmaktır. Yöntemler: Salutem plus marka tıbbi ozon cihazı, 60 gama 200 cc gaz ozon, Amsel kriterlerine göre BV tanısı konulan 102 hastaya nazogastrik kateter yardımıyla 50 cc'lik şırıngalarla intravajinal olarak uygulandı. İşlem öncesi ve sonrası hemogram parametreleri kontrol edilen hastalar, tekrarlama açısından 1., 3., 6., 9. ve 12. ay klinik kontrollerine çağrıldı ve bu hastaların muayene bulguları ve dijital verileri tedavi, komplikasyonlar ve tekrarlama açısından retrospektif olarak analiz edildi. Sonuçlar: Yaşamı tehdit eden herhangi bir komplikasyonla karşılaşılmadı. Minör yan etkiler gözlendi ve herhangi bir tedaviye gerek kalmadan kısa sürede kendiliğinden düzeldi. Tekrarlama oranlarının klasik rejim tedavilerine göre daha düşük olduğu görüldü. Ek olarak, 1 yıllık takipte en fazla 2 tekrar gözlendi. Sonuçlar: Çalışmamız bakteriyel vajinozis tedavisinde intravajinal gaz ozon tedavisinin tedavisi, tekrarı ve komplikasyonlarının değerlendirilmesi açısından literatürdeki ilk örnektir. Güvenli bir tedavi şekli olarak kabul edilen intravajinal gaz ozon tedavisinin gelecekte daha da yaygınlaşacağını ve uygulama sayısının ve sıklığının daha da artacağını düşünüyoruz. Verilerimizi doğrulamak için daha fazla sayıda hasta ile daha fazla araştırma yapılmalıdır.

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Cite This Article

Ağlamış, S. Ö., Ergani, S. Y., Şahin, E. A., Şahin, H., Şahin, T. (2025). Efficacy and safety of intravaginal gas ozone therapy in the treatment of bacterial vaginosis. Journal of Health Sciences and Medicine, Volume: 8 Issue: 5. https://doi.org/10.32322/jhsm.1734344

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