Journals / Journal of Health Sciences and Medicine / 2026 / Volume: 9 Issue: 4

Impact of preoperative anxiety on postoperative quality of life after free gingival graft surgery: a prospective cohort clinical study

Hande Güntan Erdemir(BEZMI ALEM FOUNDATION UNIVERSITY, FACULTY OF DENTISTRY)0000-0002-1470-4370
Serap Karakış Akcan(istanbul gelişim üniversitesi)0000-0003-4371-5455
Pages
—
Publication Date
2026-07-20
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: FGG surgery was associated with short-term OHQoL impairment, with recovery at one month; associations with anxiety, gender, and smoking should be interpreted cautiously.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aims: This study aimed to evaluate the effect of free gingival graft (FGG) surgery on patients’ oral health-related quality of life (OHQoL) during early healing and to assess the influence of preoperative anxiety over a one-month follow-up.
📊
Key Findings & Data:Methods: A total of 36 patients (11 males, 25 females) were enrolled.
💡
Conclusion & Impact:Conclusion: FGG surgery was associated with short-term OHQoL impairment, with recovery at one month; associations with anxiety, gender, and smoking should be interpreted cautiously.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Anxiety · gingival recession · oral health

Abstract

Aims: This study aimed to evaluate the effect of free gingival graft (FGG) surgery on patients’ oral health-related quality of life (OHQoL) during early healing and to assess the influence of preoperative anxiety over a one-month follow-up. Methods: A total of 36 patients (11 males, 25 females) were enrolled. OHQoL was assessed using OHIP-14 at baseline (T0), during the first postoperative week (T1-7), and at 1 month (T30). Demographic variables and smoking status were recorded. Preoperative anxiety was evaluated using STAI-S/T, and postoperative pain during T1-7 was assessed using VAS. Intraoperative graft and recipient site dimensions were recorded. Plaque and gingival index and keratinized tissue width were assessed at T0 and T30. Results: Total OHIP-14 scores increased significantly during T1-3 and decreased significantly at T30 compared with T0 (p<0.05). Functional limitation scores increased during T1-7, pain and discomfort during T1-2, and behavioral impact on T1, while psychological impact scores showed significant improvement during T6-7. Analgesic consumption on T1 was positively correlated with total OHIP-14 scores. Females demonstrated higher OHIP-14 scores at T0 and throughout T1-7, whereas smokers exhibited higher scores during T3-7. STAI-S scores were significantly higher in females and showed significant correlations with OHIP-14 total and pain-discomfort scores at T0 and T3-7 (p<0.05). STAI-T correlated significantly with OHIP-14 only at T7. Conclusion: FGG surgery was associated with short-term OHQoL impairment, with recovery at one month; associations with anxiety, gender, and smoking should be interpreted cautiously.

🔖

Cite This Article

Erdemir, H. G., Akcan, S. K. (2026). Impact of preoperative anxiety on postoperative quality of life after free gingival graft surgery: a prospective cohort clinical study. Journal of Health Sciences and Medicine, Volume: 9 Issue: 4. https://doi.org/10.32322/jhsm.1897335

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (41)

  1. The World Health Organization Quality of Life Assessment (WHOQOL): development and general psychometric properties. Soc Sci Med. 1998;46(12):1569-1585. doi:10.1016/s0277-9536(98)00009-4
  2. Allen PF. Assessment of oral health related quality of life. Health Qual Life Outcomes. 2003;1:40. doi:10.1186/1477-7525-1-40
  3. Slade GD. Derivation and validation of a short-form oral health impact profile. Community Dent Oral Epidemiol. 1997;25(4):284-290. doi:10. 1111/j.1600- 0528.1997.tb00941.x
  4. Locker D, Matear D, Stephens M, Lawrence H, Payne B. Comparison of the GOHAI and OHIP-14 as measures of the oral health-related quality of life of the elderly. Community Dent Oral Epidemiol. 2001;29(5):373-381. doi:10.1034/j.1600-0528.2001.290507.x
  5. Locker D. Measuring oral health: a conceptual framework. Community Dent Health. 1988;5(1):3-18.
  6. Mumcu G, Inanc N, Ergun T, et al. Oral health related quality of life is affected by disease activity in Behçet’s disease. Oral Dis. 2006;12(2):145-151. doi:10.1111/j.1601-0825.2005.01173.x
  7. Zucchelli G, Tavelli L, McGuire MK, et al. Autogenous soft tissue grafting for periodontal and peri-implant plastic surgical reconstruction. J Periodontol. 2020;91(1):9-16. doi:10.1002/JPER.19-0350
  8. Douglas de Oliveira DW, Marques DP, Aguiar-Cantuária IC, Flecha OD, Gonçalves PF. Effect of surgical defect coverage on cervical dentin hypersensitivity and quality of life. J Periodontol. 2013;84(6):768-775. doi:10.1902/jop.2012.120479
  9. Zucchelli G, Mounssif I, Mazzotti C, et al. Does the dimension of the graft influence patient morbidity and root coverage outcomes? A randomized controlled clinical trial. J Clin Periodontol. 2014;41(7):708-716. doi:10.1111/jcpe.12256
  10. Ng SK, Leung WK. Oral health-related quality of life and periodontal status. Community Dent Oral Epidemiol. 2006;34(2):114-122. doi:10. 1111/j.1600-0528.2006.00267.x
  11. Ozcelik O, Haytac MC, Seydaoglu G. Immediate post-operative effects of different periodontal treatment modalities on oral health-related quality of life: a randomized clinical trial. J Clin Periodontol. 2007;34(9): 788-796. doi:10.1111/j.1600-051X.2007.01120.x
  12. Saito A, Hosaka Y, Kikuchi M, et al. Effect of initial periodontal therapy on oral health-related quality of life in patients with periodontitis in Japan. J Periodontol. 2010;81(7):1001-1009. doi:10.1902/jop.2010.090663
  13. Del Pizzo M, Modica F, Bethaz N, Priotto P, Romagnoli R. The connective tissue graft: a comparative clinical evaluation of wound healing at the palatal donor site. A preliminary study. J Clin Periodontol. 2002;29(9):848-854. doi:10.1034/j.1600-051x.2002.290910.x
  14. Griffin TJ, Cheung WS, Zavras AI, Damoulis PD. Postoperative complications following gingival augmentation procedures. J Periodontol. 2006;77(12):2070-2079. doi:10.1902/jop.2006.050296
  15. Wessel JR, Tatakis DN. Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures. J Periodontol. 2008;79(3):425-430. doi:10.1902/jop.2008.070325
  16. Fardal Ø, McCulloch CA. Impact of anxiety on pain perception associated with periodontal and implant surgery in a private practice. J Periodontol. 2012;83(9):1079-1085. doi:10.1902/jop.2011.110562
  17. Croog SH, Baume RM, Nalbandian J. Pre-surgery psychological characteristics, pain response, and activities impairment in female patients with repeated periodontal surgery. J Psychosom Res. 1995;39(1): 39-51. doi:10.1016/0022-3999(94)00089-n
  18. Piedra-Hernández L, Batista-Cárdenas D, Gómez-Fernández A, Ramírez K. Dental anxiety and oral health-related quality of life before and after non-surgical periodontal treatment. Clin Oral Investig. 2023; 27(9):5459-5474. doi:10.1007/s00784-023-05165-1
  19. Vettore M, Quintanilha RS, Monteiro da Silva AM, Lamarca GA, Leão AT. The influence of stress and anxiety on the response of non-surgical periodontal treatment. J Clin Periodontol. 2005;32(12):1226-1235. doi:10.1111/j.1600-051X.2005.00852.x
  20. von Elm E, Altman DG, Egger M, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol. 2008; 61(4):344-349. doi:10.1016/j.jclinepi.2007.11.008
  21. Löe H. The Gingival Index, the Plaque Index and the Retention Index systems. J Periodontol. 1967;38(6):610-616. doi:10.1902/jop.1967.38.6.610
  22. Harris RJ. Clinical evaluation of 3 techniques to augment keratinized tissue without root coverage. J Periodontol. 2001;72(7):932-938. doi:10. 1902/jop.2001.72.7.932
  23. Başol ME, Karaağaçlıoğlu L, Yılmaz B. Türkçe Ağız Sağlığı Etki Ölçeğinin geliştirilmesi: OHIP-14-TR. Turkiye Klinikleri J Dent Sci. 2014;20(2):85-92.
  24. National Stress Reduction Association. STAI scoring. https://www.nsrusa.org/score.php. Accessed November 4, 2025.
  25. Zucchelli G, Mele M, Stefanini M, et al. Patient morbidity and root coverage outcome after subepithelial connective tissue and de-epithelialized grafts: a comparative randomized-controlled clinical trial. J Clin Periodontol. 2010;37(8):728-738. doi:10.1111/j.1600-051X. 2010.01550.x
  26. Arunyanak SP, Kungsadalpipob K, Wright KE, Subbalekha K, Dragan I, Mattheos N. The use of patient-related outcomes (PRO) and experience (PRE) in assessing the periodontal and implant patient. Periodontol 2000. 2024;95(1):40-50.doi:10.1111/prd.12589
  27. İşler SÇ, Uraz A, Şengül J, Çakıroğlu M, Bakırarar B, Çetiner D. Evaluation of patients’ oral health-related quality of life after harvesting free gingival graft. Cumhuriyet Dent J. 2019;22(1):11-21. doi:10.7126/cumudj.452909
  28. Mounssif I, Bentivogli V, Rendón A, et al. Patient-reported outcome measures after periodontal surgery. Clin Oral Investig. 2023;27(12):7715-7724. doi:10.1007/s00784-023-05362-y
  29. Özçelik O, Haytaç MC, Şeydaoğlu G. Periodontal cerrahi sonrası yaşam kalitesini etkileyen faktörler. Int Arch Dent Sci. 2007;28(1):67-73. doi:10.5505/iads.2007.62207
  30. Ohrn K, Jönsson B. A comparison of two questionnaires measuring oral health-related quality of life before and after dental hygiene treatment in patients with periodontal disease. Int J Dent Hyg. 2012;10(1):9-14. doi:10.1111/j.16015037.2011.00511.x
  31. Yemenoğlu H, Köse O, Cepni P. Analysis of dental anxiety levels and oral health-related quality of life of patients attending a periodontology clinic. Int J Dent Oral Res. 2024;4(2):38-46. doi:10.61139/ijdor.1497831
  32. Şen DÖ, Şengül BI, Yarkaç FU, Öncü E. Impact of platelet-rich fibrin derivatives on patient morbidity and quality of life in palatal donor sites following free gingival graft surgery: a randomized clinical trial. Clin Oral Investig. 2024;28(12):631. doi:10.1007/s00784-024-06023-4
  33. Tonetti MS, Cortellini P, Pellegrini G, et al. Xenogenic collagen matrix or autologous connective tissue graft as adjunct to coronally advanced flaps for coverage of multiple adjacent gingival recession: randomized trial assessing non-inferiority in root coverage and superiority in oral health-related quality of life. J Clin Periodontol. 2018;45(1):78-88. doi:10.1111/jcpe.12834
  34. Souza SL, Macedo GO, Tunes RS, et al. Subepithelial connective tissue graft for root coverage in smokers and non-smokers: a clinical and histologic controlled study in humans. J Periodontol. 2008;79(6):1014-1021. doi:10.1902/jop.2008.070479
  35. Eli I, Schwartz-Arad D, Baht R, Ben-Tuvim H. Effect of anxiety on the experience of pain in implant insertion. Clin Oral Implants Res. 2003; 14(1):115-118. doi:10.1034/j.1600-0501.2003.140115.x
  36. Moore R, Birn H, Kirkegaard E, Brødsgaard I, Scheutz F. Prevalence and characteristics of dental anxiety in Danish adults. Community Dent Oral Epidemiol. 1993;21(5):292-296. doi:10.1111/j.16000528.1993.tb00777.x
  37. Thomson WM, Stewart JF, Carter KD, Spencer AJ. Dental anxiety among Australians. Int Dent J. 1996;46(4):320-324.
  38. Steenen SA, Linke F, van Westrhenen R, de Jongh A. Interventions to reduce adult state anxiety, dental trait anxiety, and dental phobia: a systematic review and meta-analyses of randomized controlled trials. J Anxiety Disord. 2024;105:102891. doi:10.1016/j.janxdis.2024.102891
  39. McGrath C, Bedi R. The association between dental anxiety and oral health-related quality of life in Britain. Community Dent Oral Epidemiol. 2004;32(1):67-72. doi:10.1111/j.1600-0528.2004.00119.x
  40. Tavelli L, Asa’ad F, Acunzo R, Pagni G, Consonni D, Rasperini G. Minimizing patient morbidity following palatal gingival harvesting: a randomized controlled clinical study. Int J Periodontics Restorative Dent. 2018;38(6):e127-e134. doi:10.11607/prd.3581
  41. Burkhardt R, Hämmerle CH, Lang NP; Research Group on Oral Soft Tissue Biology & Wound Healing. Self-reported pain perception of patients after mucosal graft harvesting in the palatal area. J Clin Periodontol. 2015;42(3):281-287. doi:10.1111/jcpe.12357