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Journals / Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi / 2019 / Cilt: 33 - Sayı: 1

micro RNAs in Ovarian Cancer

Over Kanserinde mikro RNA’lar

Hüsnü Töre YAVUZŞEN
SAFİYE AKTAŞ
Hasan Bahadır SAATLİ
ZEKİYE SULTAN ALTUN
Pages
93–101
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, it is aimed to investigate the role of miRNAs in ovarian cancer studies conducted to date.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Ovarian cancer is the fifth most common cancer death in women.
📊
Key Findings & Data:Currently, gynecological examination, evaluation with ultrasound and serum measurements such as CA-125 are the standard for ovarian cancer diagnosis and treatment.
💡
Conclusion & Impact:In this review, it is aimed to investigate the role of miRNAs in ovarian cancer studies conducted to date.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Over kanseri · mikroRNA · biyobelirteç

Abstract

Ovarian cancer is the fifth most common cancer death in women. Currently, gynecological examination, evaluation with ultrasound and serum measurements such as CA-125 are the standard for ovarian cancer diagnosis and treatment. However, there is an intense need for new biomarkers that can lead to the diagnosis and treatment of the disease. MicroRNAs (miRNAs), short, protein-coding RNAs, are particularly useful stabilizing endogenous RNAs to become biomarkers in cancer. In this review, it is aimed to investigate the role of miRNAs in ovarian cancer studies conducted to date.

Özet

Over kanseri kadınlarda ölümler arasında 5. en sık ölüm nedeni olan kanserdir. Over kanseri tanı ve tedavisi için günümüzde standart olarak jinekolojik muayene, ultarason ile değerlendirme ve CA-125 gibi serum ölçümleri yer almaktadır. Ancak hem hastalığın tanısı ve tedavisi ile yol gösterebilecek yeni biyobelirteçlere yoğun bir ihtiyaç bulunmaktadır. Kısa, protein kodlamayan RNA’lar olan mikroRNA’lar (miRNA), özellikle kanserde biyobelirteç olmak için oldukça kullanışlı stabil endojen RNA’lardır. Bu derleme kapsamında over kanserinde miRNA’ların bugüne dek yapılan çalışmalarda ki rolünün irdelenmesi amaçlanmıştır.

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Cite This Article

YAVUZŞEN, H. T., AKTAŞ, S., SAATLİ, H. B., ALTUN, Z. S. (2019). micro RNAs in Ovarian Cancer. Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi, Cilt: 33 - Sayı: 1, 93–101. https://ajindex.com/articles/150621

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