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Journals / Journal of Amasya University the Institute of Sciences and Technology / 2026 / Volume: 2 Issue: 1

BIOACTIVITIES OF ISOLATED PHYTOCHEMICAL CONSTITUENTS AND EXTRACTS OF Crateva adansonii DC.

Vinujan Shanmugalingam(Palmyra Research Institute, Jaffna 40000, Sri Lanka)0000-0002-9208-4090
Saravanan Vivekanandarajah Sathasivampillai(KnowledgeLink Group, Inc., Waltham, MA 02451, USA)0000-0002-5938-0509
Pholtan Rajeev Sebastian(Provincial Herbal Garden Management Center, Trincomalee 31000, Sri Lanka)0000-0001-9341-5843
Pages
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Publication Date
2021-06-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This work supports put a basis for further studies associated with this plant species in the future.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Crateva adansonii DC. is a tree that belongs to the Capparaceae family.
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Key Findings & Data:ScienceDirect, Web of Science, Semantic Scholar, Scopus, and PubMed were utilized to detect the applicable published works from 1900 to June 2021.
💡
Conclusion & Impact:This work supports put a basis for further studies associated with this plant species in the future.
🔬Design:Review & Systematic Survey
📍Scope:2021 Verileri
⚙️Variables:Capparaceae · Crateva adansonii · ethnobotany

Abstract

Crateva adansonii DC. is a tree that belongs to the Capparaceae family. In traditional medicine, it is used to cure several disorders including constipation, earache, fevers, itch, malaria, rheumatic pains, and snakebites. Furthermore, phytochemicals including daucosterol, phytol, pyropheophorbide A, suramin, and ψ-taraxasterol have been isolated from different parts of C. adansonii. This review paper objects to scrutinize, recap, and document the reported bioactivity studies of C. adansonii. ScienceDirect, Web of Science, Semantic Scholar, Scopus, and PubMed were utilized to detect the applicable published works from 1900 to June 2021. Up to now, in vivo and in vitro scientific evidence is available for various bioactivities. In addition, analgesic, antiarthritic, antibacterial, anticancer, antifungal, antiinflammatory, antimalarial, antioxidant, and antiprotozoal activities have been observed for various parts of this plant species. Hitherto, only two bioactive compounds have been isolated from C. adansonii. Daucosterol isolated from bark showed anticancer activities and lupeol isolated from leaves showed antioxidant activities. This work supports put a basis for further studies associated with this plant species in the future.

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Cite This Article

Shanmugalingam, V., Sathasivampillai, S. V., Sebastian, P. R. (2021). BIOACTIVITIES OF ISOLATED PHYTOCHEMICAL CONSTITUENTS AND EXTRACTS OF Crateva adansonii DC.. Journal of Amasya University the Institute of Sciences and Technology, Volume: 2 Issue: 1. https://ajindex.com/articles/1505281

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References (24)

  1. Abdullahi, A., Hamzah, R., Jigam, A., Yahya, A., Kabiru, A., Muhammad, H., Sakpe, S., Adefolalu, F., Isah, M., & Kolo, M. (2012). Inhibitory activity of xanthine oxidase by fractions Crateva adansonii. Journal of Acute Disease, 1(2), 126–129. https://doi.org/10.1016/s2221-6189(13)60029-3
  2. Agboke, A.A., Attama, A. A., & Momoh, M.A. (2011). Evaluation of the antimicrobial activities of crude extract of Cryptolepis sanguinolenta and Crateva adansonii leaves and their interactions. Journal of Applied Pharmaceutical Science, 1(10), 85–89.
  3. Ahama-Esseh, K., Bodet, C., Quashie-Mensah-Attoh, A., Garcia, M., Théry-Koné, I., Dorat, J., De Souza, C., Enguehard-Gueiffier, C., & Boudesocque-Delaye, L. (2017). Anti-inflammatory activity of Crateva adansonii DC on keratinocytes infected by Staphylococcus aureus: From traditional practice to scientific approach using HPTLC-densitometry. Journal of Ethnopharmacology, 204, 26–35. https://doi.org/10.1016/j.jep.2017.04.001
  4. Burkill, H.M. (1985). The useful plants of west tropical Africa. Vol. 5. Available from: http://www.plants.jstor.org/stable/10.5555/al.apupwta5537. Accessed on 09.06.2021
  5. Gitte, T.A., Kare, M.A., & Deshmukh, A.M. (2012). Ethno- medicinal studies on barks of some medicinal plants in Marathwada (M. S.) India –I. Recent Res Sci Technol; 4:08-10.
  6. Igoli, N., Clements, C., Singla, R., Igoli, J., Uche, N., & Gray, A. (2014). Antitrypanosomal Activity & Docking Studies of Components of Crateva adansonii DC Leaves: Novel Multifunctional Scaffolds. Current Topics in Medicinal Chemistry, 14(8), 981–990. https://doi.org/10.2174/1568026614666140324120006
  7. Kewscience. (2021). Plants of the world online, Crateva adansonii DC. http://www.plantsoftheworldonline.org/taxon/urn:lsid:ipni.org:names:664873-1. Accessed on 08.06.2021
  8. Nguedia, M.Y., Tueche, A.B., Yaya, A.J.G., Yadji, V., Ndinteh, D.T., Njamen, D., & Zingue, S. (2020). Daucosterol from Crateva adansonii DC (Capparaceae) reduces 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Wistar rats. Environmental Toxicology, 35(10), 1125–1136. https://doi.org/10.1002/tox.22948.
  9. Ogunwade, I.A., Ogunbinu, A.O., Flamini, G., Cioni, P.L., & Okeniyi, S.O. (2009). Essential oil profiles of some Nigerian medicinal plants. J. Essent. Oil-Bearing Plant, 12, 225-235.
  10. Pervaiz, I., Ahmad, S., Arshad, A., Khurshid, U., & Basit, A. (2019). GC-MS metabolic profiling and anti-urease activity of non-polar fractions of Calligonum Polygonoides L. (Polygonaceae) and Crateva adansonii DC. Prodr. (Capparaceae). Tropical Journal of Pharmaceutical Research, 18(9), 1955–1960. https://doi.org/10.4314/tjpr.v18i9.25
  11. Rathinavel, T., Ammashi, S., & Shanmugam, G. (2021). Analgesic and anti-inflammatory potential of Lupeol isolated from Indian traditional medicinal plant Crateva adansonii screened through in vivo and in silico approaches. Journal of Genetic Engineering and Biotechnology, 19(1). https://doi.org/10.1186/s43141-021-00167-6
  12. Sathasivampillai, S., Rajamanoharan, P., Munday, M., & Heinrich, M., (2017). Plants currently used to treat diabetes in Sri Lankan Siddha Medicine – an ethnobotanical survey in the Eastern Province. Presented at the World Congress Integrative Medicine & Health: part three, Springer Nature, Berlin, Germany, p. 333. https://doi.org/10.1186/s12906-017-1784-2
  13. Sathasivampillai, S.V., Rajamanoharan, P.R., Heinrich, M., & Munday, M., (2015). Preparations and plants used to treat diabetes in Sri Lankan Siddha Medicine. Presented at the 3rd International Conference on Ayurveda, Unani, Siddha and Traditional Medicine, Institute of Indigenous Medicine, University of Colombo, Colombo, p. 67.
  14. Sathasivampillai, S.V., Rajamanoharan, P.R.S., & Heinrich, M., (2018). Siddha Medicine in Eastern Sri Lanka Today–Continuity and Change in the Treatment of Diabetes. Front. Pharmacol. 9. https://doi.org/10.3389/fphar.2018.01022
  15. Sathasivampillai, S.V., Rajamanoharan, P.R.S., Munday, M., & Heinrich, M., (2016). Plants used to treat diabetes in Sri Lankan Siddha Medicine – An ethnopharmacological review of historical and modern sources. Journal of Ethnopharmacology 198, 531–599. https://doi.org/10.1016/j.jep.2016.07.053
  16. Sivarajan, V.V., & Balachandran, I. (1994). Oxford and IBH Publishing Company Pvt. Ltd., 234–456.
  17. Temitope, I.B. and Felix, O.O. (2010). Phytochemical and ethnobotanical study of some selected medicinal plants from Nigeria J. Med. Plants Res., 6, pp. 1106-1118
  18. Thirumalaisamy, R., Ameen, F., Subramanian, A., Selvankumar, T., Alwakeel, S. S., & Govarthanan, M. (2020). In-Vitro and In-Silico Anti-inflammatory Activity of Lupeol Isolated from Crateva adansonii and Its Hidden Molecular Mechanism. In International Journal of Peptide Research and Therapeutics (Vol. 26, Issue 4, pp. 2179–2189). https://doi.org/10.1007/s10989-019-10006-5
  19. Thirumalaisamy, Rathinavel, Ammashi, S., & Muthusamy, G. (2018). Screening of anti-inflammatory phytocompounds from Crateva adansonii leaf extracts and its validation by in silico modeling. Journal of Genetic Engineering and Biotechnology, 16(2), 711–719. https://doi.org/10.1016/j.jgeb.2018.03.004
  20. Udeh, N., & Onoja, S. (2015). Analgesic and free radical scavenging activities of hydromethanolic extract of Crateva adansonii stem bark. Journal of Intercultural Ethnopharmacology, 4(3), 224. https://doi.org/10.5455/jice.20150430010855
  21. Zingue, S., Cisilotto, J., Tueche, A. B., Bishayee, A., Mefegue, F.A., Sandjo, L.P., Magne Nde, C.B., Winter, E., Michel, T., Ndinteh, D.T., Awounfack, C.F., Silihe, K.K., Melachio Tanekou, T.T., Creczynski-Pasa, T.B., & Njamen, D. (2016). Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo. Journal of Ethnopharmacology, 190, 183–199. https://doi.org/10.1016/j.jep.2016.06.004
  22. Zingue, S., Fogang, R.C.M., Njuh, A.N., Tchuidjou, D., Tueche, A.B., Ndinteh, D.T., & Njamen, D. (2018). In vitro and in vivo antiestrogenic effects of dichloromethane-methanol extract of Crateva adansonii DC. Indian Journal of Experimental Biology, 56(11), 795–802.
  23. Zingue, S., Gbaweng Yaya, A.J., Michel, T., Ndinteh, D. T., Rutz, J., Auberon, F., Maxeiner, S., Chun, F. K. H., Tchinda, A. T., Njamen, D., & Blaheta, R. A. (2020). Bioguided identification of daucosterol, a compound that contributes to the cytotoxicity effects of Crateva adansonii DC (Capparaceae) to prostate cancer cells. Journal of Ethnopharmacology, 247, 112251. https://doi.org/10.1016/j.jep.2019.112251
  24. Kewscience. (2021). Plants of the world online, Crateva adansonii DC. http://www.plantsoftheworldonline.org/taxon/urn:lsid:ipni.org:names:664873-1. Accessed on 08.06.2021