Molar Gebelik Sonucu Gelişen Hipertiroidizm Olgusunda Plazmaferez Tedavisi

Key Findings & Data:Laboratu- var tetkiklerinde artmış human chorionic gonadotropin (hCG), baskılanmış tiroid stimulan hormon (TSH) ve artmış serbest ti- roid hormon düzeyleri görüldü.

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Conclusion & Impact:Histopatolojik incelemede non-invaziv mol hidati- form tanısı doğrulandı.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

18 yaşında kadın hasta karın ağrısı, yorgunluk, bulantı, kusma, ellerde titreme ve vajinal kanama şikayeti ile başvurdu. Laboratu- var tetkiklerinde artmış human chorionic gonadotropin (hCG), baskılanmış tiroid stimulan hormon (TSH) ve artmış serbest ti- roid hormon düzeyleri görüldü. Laboratuar tetkikleri ile birlikte tiroid doppler ve uterus ultrasonografi incelemesi sonucunda molar gebelik sonucu gelişen hipertiroidizm tanısı düşünüldü. Plazmaferez tedavisi ile hastanın semptomların da düzelme ve serbest tiroid hormonlarında normal düzeye gerileme sağlandı. Plazmaferez tedavisi sonrası hastaya dilatasyon ve küretaj tedavisi uygulandı. Histopatolojik incelemede non-invaziv mol hidati- form tanısı doğrulandı.

Özet

We recently encountered the case of an 18-year-old female com- plaining of abdominal pain, fatigue, nausea, vomiting, tremor of the hands, and vaginal bleeding. Her blood test revealed highly elevated human chorionic gonadotropin (hCG) levels, suppressed thyroid-stimulating hormone (TSH) levels, and in- creased free thyroid hormone levels. Molar pregnancy and hyper- thyroidism were suspected based on highly elevated hCG levels and suppressed TSH levels with the co-existence of ultrasono- graphic findings of the uterus and thyroid Doppler images. Her symptoms and thyroid hormone levels responded well to plas- mapheresis. Subsequently, the patient underwent dilatation and curettage for hydatidiform mole. Histopathology of the products verified the diagnosis of complete hydatidiform mole with no in- vasion. The patient is currently stable, and her hCG and thyroid hormone levels are within normal reference ranges.

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Cite This Article

KİRAC, C. O., BALDANE, S., KEBAPCILAR, A. G., İPEKÇİ, S. H., UÇAR, M. G., ÇELİK, Ç., KEBAPCILAR, L. (2018). Molar Gebelik Sonucu Gelişen Hipertiroidizm Olgusunda Plazmaferez Tedavisi. Bezmiâlem Science, Cilt: 6 - Sayı: 4, 320–322. https://ajindex.com/articles/150113

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