Journals / Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi / 2020 / Cilt: 33 - Sayı: 2

Rapid efficacy of mirtazapine in the treatment of hyperemesis gravidarum with esophagus perforation and ketonuria in a normoglycemic patient: a case report

Pages
206–209
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, the appropriateness of using mirtazapine in the treatment of pregnant patients needs to be discussed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hyperemesis gravidarum is a medical condition that may cause serious consequences for fetus and mother.
📊
Key Findings & Data:The aim of our report was to present a successful treatment with mirtazapine for a 28-year-old pregnant patient who developed esophageal perforation and ketonuria while being normoglycemic due to severe and treatment-resistant hyperemesis gravidarum.
💡
Conclusion & Impact:However, the appropriateness of using mirtazapine in the treatment of pregnant patients needs to be discussed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Hyperemesis gravidarum is a medical condition that may cause serious consequences for fetus and mother. The treatment regimen in patients with severe and treatment-resistant conditions is unclear. While antiemetics are known to be used for hyperemesis gravidarum in the literature, mirtazapine has been used effectively in some treatment-resistant cases. On the other hand, to the best of our knowledge, no reports on the efficacy of mirtazapine in cases of severe and treatment-resistant hyperemesis gravidarum have been published in the literature. The aim of our report was to present a successful treatment with mirtazapine for a 28-year-old pregnant patient who developed esophageal perforation and ketonuria while being normoglycemic due to severe and treatment-resistant hyperemesis gravidarum. This case revealed that mirtazapine may be effective even in severe cases of hyperemesis gravidarum. In addition, the effectiveness of mirtazapine in the treatment of hyperemesis gravidarum has been confirmed. However, the appropriateness of using mirtazapine in the treatment of pregnant patients needs to be discussed.

🔖

Cite This Article

KUL, A. T., GUNDOGMUS, I., AYDİN, M. B. (2020). Rapid efficacy of mirtazapine in the treatment of hyperemesis gravidarum with esophagus perforation and ketonuria in a normoglycemic patient: a case report. Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi, Cilt: 33 - Sayı: 2, 206–209. https://ajindex.com/articles/149137

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. de Boer TH, Nefkens F, van Helvoirt A, van Delft AM. Differences in modulation of noradrenergic and serotonergic transmission by the alpha-2 adrenoceptor antagonists, mirtazapine, mianserin and idazoxan. J Pharmacol Exp Ther 1996; 277:852-860
  2. Guclu S, Gol M, Dogan E, Saygili U. Mirtazapine use in resistant hyperemesis gravidarum: report of three cases and review of the literature. Arch Gynecol Obstet 2005; 272:298-300
  3. Ozcankaya R, Acar A. A comparison of amitriptyline and mırtazapine side effects in depression treatment. Bull Clin Psychopharmacol 2001; 11:17-27
  4. Hrdlicka M, Beranova I, Zamecnikova R, Urbanek T. Mirtazapine in the treatment of adolescent anorexia nervosa. Case-control study. Eur Child Adolesc Psychiatry 2008; 17:187- 189
  5. Pae CU. Low-dose mirtazapine may be successful treatment option for severe nausea and vomiting. Prog Neuropsychopharmacol Biol Psychiatry 2006; 30:1143-1145
  6. Kim SW, Shin IS, Kim JM, Kang HC, Mun JU, Yang SJ, et al. Mirtazapine for severe gastroparesis unresponsive to conventional prokinetic treatment. Psychosomatics 2006; 47:440- 442
  7. Simsek Y, Celik O, Yilmaz E, Karaer A, Yildirim E, Yologlu S. Assessment of anxiety and depression levels of pregnant women with hyperemesis gravidarum in a case-control study. J Turk Ger Gynecol Assoc 2012; 13:32-36
  8. Kender EE, Yuksel G, Ger C, Ozer U. Eating attitudes, depression and anxiety levels of patients with hyperemesis gravidarum hospitalized in an obstetrics and gynecology clinic. Dusunen Adam The Journal of Psychiatry and Neurological Sciences 2015; 28:119-126
  9. Chan RL, Olshan AF, Savitz DA, Herring AH, Daniels JL, Peterson HB, et al. Maternal influences on nausea and vomiting in early pregnancy. Matern Child Health J 2011; 15:122-127
  10. Buyukkurt S, Demir SC, Ozgunen FT, Evruke IC, Kadayifci O, Guzel AB. Evaluation and Treatment of the Patients with Nausea and Vomiting in Pregnancy: Review. Turkiye Klinikleri J Gynecol Obst 2008; 18:106-116
  11. Kavakci O, Yenicesu GI. Eye movement desensitization and reprocessing [EMDR] for hyperemesis gravidarum: a case series. Dusunen Adam The Journal of Psychiatry and Neurological Sciences 2014; 27:335-341
  12. Saks B. Mirtazapine: treatment of depression, anxiety, and hyperemesis gravidarum in the pregnant patient. A report of 7 cases. Arch Womens Ment Health 2001; 3:165-170
  13. Naguy A. Mirtazapine for major depression developed after hyperemesis gravidarum. Am J Ther 2019; 26:e661-e662
  14. Rohde A, Dembins