Journals / Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / 2018 / Cilt: 5 - Sayı: 3

Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery

Pages
80–83
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Lenght of stay in intesive care unit and overall were significantly higher in patients with SH (p: 0.0102 and p: 0.0004 respectively).

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Subclinical hyperthyroidsm is associated with negative effects on cardiovascular system.
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Key Findings & Data:Patient’s clinical characteristics, surgical details and post-operative mortality and morbidities were recorded.Patients were divided into two groups according to their TSH level with cut-off point of 0,35 was assumed.
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Conclusion & Impact:Lenght of stay in intesive care unit and overall were significantly higher in patients with SH (p: 0.0102 and p: 0.0004 respectively).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:subclinical hyperthroidism · cardio-vascular disease · coronary artery by-pass

Abstract

Introduction: Subclinical hyperthyroidsm is associated with negative effects on cardiovascular system. We aimed to evaluate the association between pre-operative thyroid hormones and post-operative outcome in patients undergoing coronary artery by-pass graft (CABG) surgery. Methods: A hundred and eighty nine patients with isolated CABG surgery were included into the study. Patient’s clinical characteristics, surgical details and post-operative mortality and morbidities were recorded.Patients were divided into two groups according to their TSH level with cut-off point of 0,35 was assumed. Results: The first group consists of 16 patients (9%) with subclinical hyperthyroid (SH) and the second group includes 173 euthyroid patients. In post-operative period; the incidence of arrhythmia, renal failure and inotropy requirement were significantly higher in SH group (p<.0001, p: 0.0002 and p<.0001 respectively) The incidence of peri-operative mortality was similar between groups. (p: 0.0860). Lenght of stay in intesive care unit and overall were significantly higher in patients with SH (p: 0.0102 and p: 0.0004 respectively). Discussion and Conclusion: Pre-operative subclinical hyperthyroidsm didn’t effect peri-operative mortality but may lead to higher postoperative complications such as arrhythmia, renal failure and low cardiacoutput syndrome in patients undergoing CABG surgery.

Özet

Introduction: Subclinical hyperthyroidsm is associated with negative effects on cardiovascular system. We aimed to evaluate the association between pre-operative thyroid hormones and post-operative outcome in patients undergoing coronary artery by-pass graft (CABG) surgery. Methods: A hundred and eighty nine patients with isolated CABG surgery were included into the study. Patient’s clinical characteristics, surgical details and post-operative mortality and morbidities were recorded.Patients were divided into two groups according to their TSH level with cut-off point of 0,35 was assumed. Results: The first group consists of 16 patients (9%) with subclinical hyperthyroid (SH) and the second group includes 173 euthyroid patients. In post-operative period; the incidence of arrhythmia, renal failure and inotropy requirement were significantly higher in SH group (p<.0001, p: 0.0002 and p<.0001 respectively) The incidence of peri-operative mortality was similar between groups. (p: 0.0860). Lenght of stay in intesive care unit and overall were significantly higher in patients with SH (p: 0.0102 and p: 0.0004 respectively). Discussion and Conclusion: Pre-operative subclinical hyperthyroidsm didn’t effect peri-operative mortality but may lead to higher postoperative complications such as arrhythmia, renal failure and low cardiacoutput syndrome in patients undergoing CABG surgery.

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Cite This Article

AVCI, E., DOLAPOĞLU, A., KIZILGÜL, M. (2018). Effect of Subclinical Hyperthyroidsm on the Outcome of Coronary Artery Graft Bypass Surgery. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Cilt: 5 - Sayı: 3, 80–83. https://ajindex.com/articles/148675

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References (1)

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