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Journals / ANKEM Dergisi / 2014 / Cilt: 28 - Sayı: 2

Pegylated Interferon Alpha-Induced Ulcerative Oral Lichen Planus That Formed on the Buccal Mucosa and Lip

PEGİLE İNTERFERON ALFANIN İNDÜKLEDİĞİ DUDAK VE BUKKAL MUKOZADA OLUŞAN ÜLSERATİF ORAL LİKEN PLANUS

Nevin İNCE
Aslı ŞENOL
Ali İhsan GÜLEÇ
Mehmet Faruk GEYİK
Pages
68–71
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It should be taken into account that ulcerative lichen planus on lips may also develop in addition to oral mucosal lesions caused by PEG IFN-alpha.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 55 year-old male patient was ref erred to our outpatient clinic with ulcerative lesions on her lower lip and oral muco- sa in 42th week of pegylated interf eron alpha (PEG IFN-alpha) treatment f or chronic hepatitis C.
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Key Findings & Data:Ulcerative oral lichen planus (OLP) was diagnosed with the biopsy obtained f rom the lesions.
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Conclusion & Impact:It should be taken into account that ulcerative lichen planus on lips may also develop in addition to oral mucosal lesions caused by PEG IFN-alpha.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 55 year-old male patient was ref erred to our outpatient clinic with ulcerative lesions on her lower lip and oral muco- sa in 42th week of pegylated interf eron alpha (PEG IFN-alpha) treatment f or chronic hepatitis C. Ulcerative oral lichen planus (OLP) was diagnosed with the biopsy obtained f rom the lesions. OLP cases, that result, recur or exacerbate as a result of interf eron therapy, have been presented in literature. It should be taken into account that ulcerative lichen planus on lips may also develop in addition to oral mucosal lesions caused by PEG IFN-alpha.

Özet

Kronik hepatit C (KHC) tanısıyla pegile interf eron alf a (PEG IFN-alf a) tedavisi başlanan 55 yaşında erkek hasta, teda- visinin 42. haf tasında alt dudakta ve oral mukozada ülsere lezyon gelişmesi nedeniyle kliğimize başvurmuştur. Lezyonlardan alınan biyopsi sonucunda ülseratif oral liken planus (OLP) saptanmıştır. OLP, etiyolojisi tam olarak bilinmeyen, deri ve mükoz membranları tutabilen bir hastalıktır. İnterf eron tedavisi sonucu alevlenen veya yeni ortaya çıkan OLP vakaları litera- türde bildirilmiştir. PEG IFN-alf a’ya bağlı oral mukoza lezyonları ile birlikte dudakta da ülseratif liken planus gelişebileceği göz önünde bulundurulmalıdır.

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Cite This Article

İNCE, N., ŞENOL, A., GÜLEÇ, A. İ., GEYİK, M. F. (2014). Pegylated Interferon Alpha-Induced Ulcerative Oral Lichen Planus That Formed on the Buccal Mucosa and Lip. ANKEM Dergisi, Cilt: 28 - Sayı: 2, 68–71. https://ajindex.com/articles/148509

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References (13)

  1. Aman W, Mousa S, Shiha G, Mousa SA. Current status and future directions in the management of chronic hepatitis C, Virol J 2012;2;9:57
  2. Carrozzo M, Brancatello F, Dametto E et al. Hepatitis C virus-associated oral lichen planus: is geographical heterogeneity related to HLA-DR6? J Oral Pathol Med 2005;34(4):204-8.
  3. Chainani-Wu N, Lozada-Nur F, Terrault N. Hepatitis C virus and lichen planus: a review, Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98(2):171-83.
  4. Dalekos GN, Christodoulou D, Kistis KG, Zervo EK, Hatzis J, Tsianos EV. A prospective evaluation of dermatological side effects during alpha inter- feron therapy for chronic viral hepatitis, Eur J Gastroenterol Hepatol 1998;10(11):933-9.
  5. Dusheiko G. Side effects of alpha interferon in chronic hepatitis C, Hepatology 1997;26(3 Suppl 1):S112-21.
  6. Erbağcı Z. HCV enfeksiyonunun interferonla tedavisi sırasında ülserleşen lokalize liken planus, TURKDERM 1999;33(1):53-4
  7. Gencoglan G, İnanir İ, Sahin O, Gunduz K. Imiquimod 5 % cream for isolated lichen planus of the lip, J Dermatolog Treat 2011;22(1):55-9.
  8. Grossmann Sde M, Teixeira R, de Aguiar MC, do Carmo MA. Exacerbation of oral lichen planus lesions during treatment of chronic hepatitis C with pegylated interferon and ribavirin, Eur J Gastroenterol Hepatol 2008;20(7):702-6.
  9. Guijarro Guijarro B, López Sánchez AF, Hernández Vallejo G. Presence of lichen planus during a cour- se of interferon alpha-2a therapy for a viral chro- nic C hepatitis, Med Oral 2001;6(5):358-63
  10. Guner R, Keske S, Hasanoglu I, Tasyaran M. Pityriasis rosea associated with pegylated interfe- ron alpha and ribavirin treatment in a patient with chronic hepatitis C, Balkan Med J 2013;30(2): 253-4.
  11. Ismail SB, Kumar SK, Zain RB. Oral lichen planus and lichenoid reactions: etiopathogenesis, diagno- sis, management and malignant transformation, J Oral Sci 2007;49(2):89-106.
  12. Itin PH, Schiller P, Gilli L, Buechner SA. Isolated lichen planus of the lip, Br J Dermatol 1995;132(6): 1000-2.
  13. Kartal ED, Colak H, Ozgunes I, Usluer G. Exacerb