Journals / Akademik Gastroenteroloji Dergisi / 2015 / Cilt: 14 - Sayı: 3

Oesophageal heterotopic gastric mucosa: how often? How important? A case-control study

Özofageal heterotopik gastrik mukoza: ne kadar sık? Ne kadar önemli? Bir vaka-kontrol çalışması

Pages
106–112
DOI
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Conclusion: The presence of heterotopic gastric mucosa was more frequent in patients with upper oesophageal symptoms resistant to treatment; male patients under 50 years of age; and, in patients with a history of Barrett’s esophagus.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Aims: Heterotopic gastric mucosa is a columnar mucosal islet, commonly located in the cervical esophagus, that is usually asymptomatic and nonprogressive.
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Key Findings & Data:Materials and Method: In this study, we retrospectively analyzed data from patients who underwent gastroscopy between January 2009 and December 2013, excluding procedures performed for unknown indications, or repeated, or urgent gastroscopies.
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Conclusion & Impact:Conclusion: The presence of heterotopic gastric mucosa was more frequent in patients with upper oesophageal symptoms resistant to treatment; male patients under 50 years of age; and, in patients with a history of Barrett’s esophagus.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Background and Aims: Heterotopic gastric mucosa is a columnar mucosal islet, commonly located in the cervical esophagus, that is usually asymptomatic and nonprogressive. In this study, we aimed to evaluate the clinicopathological features of heterotopic gastric mucosa cases in our clinic that were diagnosed using endoscopy. Materials and Method: In this study, we retrospectively analyzed data from patients who underwent gastroscopy between January 2009 and December 2013, excluding procedures performed for unknown indications, or repeated, or urgent gastroscopies. After completing epidemiological analysis, an age and gender matched control group was attained from patients whose gastroscopy was done due to dyspepsia. We compared clinico- pathological characteristics of the heterotopic gastric mucosa and con- trol groups. Results: A total of 12.767 patients, 7.244 (56.7%) female, were included in the study. Mean patient age was 52.4±16.5 years. Heterotopic gastric mucosa accounted for 137 (1.1%) of the cases. Ninety percent were in the proximal esophagus. The highest hetero- topic gastric mucosa rates in follow up examiniations were idenntified as: Barrett’s esophagus (6.5%), upper esophageal symptoms (2%), and nausea/vomiting (1.7%). Heterotopic gastric mucosa prevalence was 0.7% in females and 1.5% in males (p <0.01). The average age of the heterotopic gastric mucosa group was significantly younger than the non- heterotopic gastric mucosa group (47.9±15 and 52.5±16, p <0.01). Conclusion: The presence of heterotopic gastric mucosa was more frequent in patients with upper oesophageal symptoms resistant to treatment; male patients under 50 years of age; and, in patients with a history of Barrett’s esophagus.

Özet

Giriş ve Amaç: Heterotopik gastrik mukoza genellikle servikal özofagusta yerleşen, çoğunlukla asemptomatik olan ve ilerleyici olmayan kolumnar mukozal adacıktır. Çalışmamızda kliniğimizde endoskopik olarak heterotopik gastrik mukoza tanısı konan vakaların klinikopatolojik özelliklerini değerlendirmeyi amaçladık. Gereç ve Yöntem: Çalışmada Ocak 2009-Aralık 2013 tarihleri arasında gastroskopi yapılan vakaların verileri retrospektif olarak incelendi. Endikasyonu bilinmeyen, mükerrer ve acil vakalar çalışma dışı bırakıldı. Epidemiyolojik analizler sonrası dispepsi yakınması ile gastroskopi yapılan gruptan heterotopik gastrik mukoza olguları ile yaş ve cinsiyet eşlenik bir kontrol grubu oluşturuldu. Heterotopik gastrik mukoza ve kontrol grubunun klinikopatolojik özellikleri karşılaştırıldı. Bulgular: Çalışmaya 7244’ü kadın (%56.7) toplam 12.767 hasta alındı. Hastaların yaş ortalaması 52.4±16.5 yıl idi. 137 vakada (%1.1) heterotopik gastrik mukozaya rastlandı. Vakaların %90.1’i proksimal özofagusta idi. Heterotopik gastrik mukoza oranı en yüksek işlem endikasyonları; Barrett özofagus kontrol (%6.5), üst özofageal semptomlar (%2) ve bulantı kusma (%1.7) idi. Heterotopik gastrik mukoza prevalansı kadınlarda %0.7 iken erkeklerde %1.5 bulundu (p<0.01). Heterotopik gastrik mukoza grubunun yaş ortalaması non-heterotopik gastrik mukoza grubuna göre anlamlı biçimde düşüktü (47.9±15 ve 52.5±16, p<0.01). Sonuç: Tedaviye dirençli üst özofageal şikayetleri olan, 50 yaşın altındaki erkek olgularda ve Barrett özofagusu öyküsü olan hastalarda heterotopik gastrik mukoza bulunma ihtimali daha yüksektir.

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Cite This Article

KÖKSAL, A. R., ALKIM, H., BOĞA, S., BAYRAM, M., ŞEN, İ., ÖZAĞARI, A. A., ALKIM, C. (2015). Oesophageal heterotopic gastric mucosa: how often? How important? A case-control study. Akademik Gastroenteroloji Dergisi, Cilt: 14 - Sayı: 3, 106–112. https://ajindex.com/articles/148379

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