Journals / İstanbul Tıp Fakültesi Dergisi / 2021 / Cilt: 84 - Sayı: 2

GLIOBLASTOMA PRESENTED WITH DEPRESSION AND PERSONALITY CHANGES: A CASE REPORT

DEPRESYON VE KİŞİLİK DEĞİŞİKLİLERİ İLE ORTAYA ÇIKAN GLİOBLASTOMA: BİR OLGU SUNUMU

Pages
281–284
Publication Date
2021-04-25
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case, a 7x4 cm-sized lesion with a mass effect from the left frontoparietal region and extending to the temporal lobe was found.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Glioblastoma is the most common poor prognosis brain tumor in adults.
📊
Key Findings & Data:In this article, a 57-year-old man admitted to emergency unit with social isolation, anhedonia, loss of appetite, sleep disturbances and personality changes is reported.
💡
Conclusion & Impact:In this case, a 7x4 cm-sized lesion with a mass effect from the left frontoparietal region and extending to the temporal lobe was found.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Glioblastoma · anhedoni · depresyon

Abstract

Glioblastoma is the most common poor prognosis brain tumor in adults. Although neurological signs are often seen as first symptoms at clinical course of GBM, pychiatric symptoms also accompany the presentation. Mood and personality changes, anxiety and psychosis are the most common psychiatric symptoms in presentation of GBM. In this article, a 57-year-old man admitted to emergency unit with social isolation, anhedonia, loss of appetite, sleep disturbances and personality changes is reported. In this case, a 7x4 cm-sized lesion with a mass effect from the left frontoparietal region and extending to the temporal lobe was found.

Özet

Glioblastoma, erişkinlerde en sık görülen kötü prognozlu bir beyin tümörüdür. Her ne kadar GBM’nin klinik seyrinde ilk semptomlar nörolojik belirtiler şeklinde olsa da, psikiyatrik belirtiler de eşlik edebilir. Duygudurum ve kişilik değişiklikleri, anksiyete ve psikoz GBM’de en sık görülen psikiyatrik belirtilerdir. Bu yazıda, acil servise sosyal içe çekilme, anhedoni, iştahsızlık, uyku düzensizliği ve kişilik değişiklileri ile başvuran 57 yaşında bir erkek hasta bildirilmiştir. Bu olguda, beyin görüntüleme incelemelerinde 7x4 cm büyüklüğünde sol frontoparietal bölgeden başlayıp temporal loba uzanan ve kitle etkisi gösteren bir lezyon saptandı.

🔖

Cite This Article

KAPICI, Y., KAPICI, O. B., EGELİ, A., TEKİN, A. (2021). GLIOBLASTOMA PRESENTED WITH DEPRESSION AND PERSONALITY CHANGES: A CASE REPORT. İstanbul Tıp Fakültesi Dergisi, Cilt: 84 - Sayı: 2, 281–284. https://ajindex.com/articles/148171

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Ostrom QT, Gittleman H, Fulop J, Liu M, Blanda R, Kromer C, et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2008-2012. Neuro Oncol 2015
  2. 17(Suppl 4):iv1-62. [CrossRef] 2. Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med 2008
  3. [CrossRef] 3. Keschner M, Bender MB, Strauss I. Mental symptoms associated with brain tumor: a study of 530 verified cases. JAMA 1938
  4. [CrossRef] 4. Madhusoodanan S, Danan D, Moise D. Psychiatric manifestations of brain tumors: diagnostic implications. Expert Rev Neurother 2007
  5. 7(4):343-9. [CrossRef] 5. Mugge L, Mansour TR, Crippen M, Alam Y, Schroeder J. Depression and glioblastoma, complicated concomitant diseases: A systemic review of published literature. Neurosurg Rev 2020
  6. 43(2):497-511. [CrossRef] 6. Leo RJ, Frodey JN, Ruggieri ML. Subtle neuropsychiatric symptoms of glioblastoma multiforme misdiagnosed as depression. BMJ Case Reports CP 2020
  7. 13(3):e233208 [CrossRef] 7. Cheema FA, Badr A, Iqbal J. Glioblastoma multiforme presenting as treatmentresistant depression. J Neuropsychiatry Clin Neurosci 2010
  8. 22(1):123-e126. [CrossRef] 8. Madhusoodanan S, Danan D, Moise D. Psychiatric manifestations of brain tumors: diagnostic implications. Expert Rev Neurother 2007
  9. 7(4):343-9. [CrossRef] 9. Moise D, Madhusoodanan S. Psychiatric symptoms associated with brain tumors: a clinical enigma. CNS Spectr 2006
  10. 11(1):28-31. [CrossRef] 10. Yapıcı-Eser H, Onay A, Öztop-Çakmak Ö, Egemen E, Vanlı-Yavuz EN, Solaroğlu İ. Rare case of glioblastoma multiforme located in posterior corpus callosum presenting with depressive symptoms and visual memory deficits. BMJ Case Rep 2016
  11. pii:bcr2016216505. [CrossRef] 11. Zhang YY, Ruan LX, Zhang S. Rapid progression of glioblastoma multiforme: a case report. Oncol Lett 2016
  12. 12(6):4803-6. [CrossRef] 12. Szczepanski SM, Knight RT. Insights into human behavior from lesions to the prefrontal cortex. Neuron 2014
  13. 83(5):1002-18. [CrossRef] 13. Dixon ML, Thiruchselvam R, Todd R, Christoff K. Emotion and the prefrontal cortex: an integrative review. Psychol Bull 2017
  14. 143(10):1033. [CrossRef] 14. Franssen A, Sienaert P. Temporal glioblastoma presenting as catatonia. BMJ Case Rep 2019
  15. 12(3):e224017. [CrossRef] 15. Petzold J, Severus E, Meyer S, Bauer M, Daubner D, Krex D, Juratli TA. Glioblastoma multiforme presenting as postpartum depression: a case report. J Med Case Rep 2018
  16. 12(1):1-4. [CrossRef] 16. Zivković N, Marko