Journals / Androloji Bülteni / 2017 / Cilt: 19 - Sayı: 2

The impact of environmental stress factors on sperm

Çevresel stres faktörlerinin sperm hücreleri üzerine etkisi

Pages
61–64
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this compilation, it is aimed to show the effects of new environmental factors on spermatogenesis which we are frequently exposed and arise due to technological development

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Sperm cells are morphologically, functionally and metabolically very different from other cells in the body.
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Key Findings & Data:The increase in the numbers of defective sperms can be attributed to genetic and environmental factors.
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Conclusion & Impact:In this compilation, it is aimed to show the effects of new environmental factors on spermatogenesis which we are frequently exposed and arise due to technological development
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Sperm cells are morphologically, functionally and metabolically very different from other cells in the body. For this reason, the response of sperm cells to stress factors is different from somatic cells. The increase in the numbers of defective sperms can be attributed to genetic and environmental factors. Increasing environmental toxins, electromagnetic radiation and xenobiotics have a negative effect on the sperm cells, parallel to the development of industrial and technological industries. The negative effects of toxins, chemicals, pesticides, metal ions and radiation on sperm concentration, motility, morphology and nuclear structure have been proven in the literature. In studies comparing fertility with semen parameters, it has been shown that persistent environmental pollutants are one of the factors affecting reproductivity. The presence of active pharmacological agents in the waste water is another proven factor that Deoxyribonucleic acid (DNA) fragmentation and sperm cell damage can be increased. Considering all these, it seems that many environmental agents can reduce male reproductive potential by producing defective sperm cells. In this compilation, it is aimed to show the effects of new environmental factors on spermatogenesis which we are frequently exposed and arise due to technological development

Özet

Sperm hücreleri morfolojik, fonksiyonel ve metabolik açıdan vücuttaki diğer hücrelere göre oldukça farklılık gösterir. Bu nedenle, sperm hücrelerinin stres faktörlerine tepkisi somatik hücrelerden farklı olmaktadır. Defektif sperm sayısındaki artış genetik ve çevresel faktörlere bağlanabilir. Endüstriyel ve teknolojik sanayinin gelişmesine paralel olarak, artan çevresel toksinler, elektromanyetik radyasyon ve ksenobiyotiklerin sperm hücreleri üzerine negatif etkisi de ön plana çıkmaktadır. Toksinlerin, kimyasalların, tarım ilaçlarının, metal iyonlarının ve radyasyonun, sperm konsantrasyonu, hareketliliği, morfolojisi ve nükleer yapısı üzerine kötü etkileri literatürde kanıtlanmıştır. Semen parametreleri ile doğurganlığı karşılaştıran çalışmalarda, kalıcı çevresel kirleticilerin üremeyi etkileyen faktörlerden biri olduğu gösterilmiştir. Atık sularda aktif farmakolojik ajanların olmasının sperm Deoksiribonükleik asit (DNA) fragmantasyonunu arttırdığı ve sperm hücre hasarı yapabildiği, kanıtlanmış diğer bir faktördür. Tüm bunlar göz önüne alındığında, birçok çevresel ajanın sperm hücrelerinde defektler meydana getirerek erkek üreme potansiyelini düşürdüğü görülmektedir. Bu derlemede, sık maruz kalınan ve teknolojik gelişmeye bağlı olarak ortaya çıkan yeni çevresel faktörlerin spermatogenez üzerine etkilerinin gösterilmesi amaçlanmaktadır

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Cite This Article

PELİT, E. S., KATI, B., AKIN, Y., YENİ, E. (2017). The impact of environmental stress factors on sperm. Androloji Bülteni, Cilt: 19 - Sayı: 2, 61–64. https://ajindex.com/articles/147572

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References (14)

  1. KAYNAKLAR 1. Aitken RJ. Human spermatozoa: revelations on the road to conception. F1000Prime 2013
  2. doi: 10.12703/P5-39 2. Buck Louis GM, Sundaram R, Schisterman EF, Sweeney AM, Lynch CD, et al. Persistent environmental pollutants and couple fecundity: the LIFE study. Environ Health Perspect 2013
  3. 231– 6. doi: 10.1289/ehp.1205301 3. Rocco L, Peluso C, Cesaroni F, Morra N, Cesaroni D, Stingo V. Genomic Damage in Human Sperm Cells Exposed In Vitro to Environmental Pollutants. J Environment Analytic Toxicol 2012
  4. doi: 10.4172/2161-0525.1000117 4. Klassen CD, Amdur MO, Doull L. Casarett and Doull’s Toxicology: the basic science of poisons, 3rd ed. New York: Macmillan Publishing Co.
  5. Overstreet JW, Samuels SJ, Day P, Hendrickx AG, Prahalada S, et al. Early indicators of male reproductive toxicity. Risk Anal 1988
  6. 21–6. 6. Anderson D, Yu TW, Browne MA. The use of the same image analysis system to detect genetic damage in human lymphocytes treated with doxorubicinin the Comet and fluorescence in situ hybridization (FISH) assay. Mutat Res 1997
  7. 69–77. 7. Sakkas D, Alvarez JG. Sperm DNA fragmentation: mechanisms of origin, impact on reproductive outcome, and analysis. Fertil Steril 2010
  8. 1027–36. doi: 10.1016/j.fertnstert.2009.10.046 8. Delbès G, Hales BF, Robaire B. Toxicants and human sperm chromatin integrity. Mol Hum Reprod 2010
  9. 14–22. doi: 10.1093/molehr/gap087 9. Aitken RJ, De Iuliis GN, Finnie JM, Hedges A, McLachlan RI. Analysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: development of diagnostic criteria. Hum Reprod 2010
  10. 2415–26. doi: 10.1093/ humrep/deq214 10. Delbès G, Hales BF, Robaire B. Toxicants and human sperm chromatin integrity. Mol Hum Reprod 2010
  11. 14–22. doi: 10.1093/molehr/gap087 11. Garolla A, Torino M, Miola P, Caretta N, Pizzol D, Menegazzo M, Bertoldo A, Foresta C. Twenty-four-hour monitoring of scrotal temperature in obese men and men with a varicocele as a mirror of spermatogenic function. Hum Reprod 2015
  12. 1006–13. doi: 10.1093/humrep/dev057 12. Sheynkin Y, Jung M, Yoo P, Schulsinger D, Komaroff E. Increase in scrotal temperature in laptop computer users. Hum Reprod 2005
  13. 452–5. doi: 10.1093/humrep/deh616 13. Levine RJ, Brown MH, Bell M, Shue F, Greenberg GN, et al. Airconditioned environments do not prevent deterioration of human semen quality during the summer. Fertil Steril 1992
  14. 1075–83. 14. Levine RJ. Seasonal variation of semen quali