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Journals / Current Perspectives on Medicinal and Aromatic Plants / 2026 / Volume: 9

Mangrove-Derived Phytochemicals: Therapeutic Role in Depression and Hypertension Management

Mangrovdan Elde Edilen Fitokimyasallar: Depresyon ve Hipertansiyon Yönetiminde Terapötik Rolü

Dudu Altıntaş Gündüz(DÜZCE ÜNİVERSİTESİ)0000-0002-5133-2799
Ufuk Koca(GAZİ ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİ)0000-0002-5216-7588
Pages
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Publication Date
2026-07-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The present study will investigate the impact of mangroves on hypertension and depression.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Abstract Mangrove is the name given to a group of trees and shrubs living in salt soils that provide oxygen to the plant through their lenticels in marshy and low-oxygen soils.
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Key Findings & Data:Mangroves are an important source for a wide range of wood, such as construction, shelters, fences, and non-wood forest products such as honey, sugar, alcohol, vinegar, foliage for fodder and cattle.
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Conclusion & Impact:The present study will investigate the impact of mangroves on hypertension and depression.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Antidepressant · Antihypertensive · Mangroves

Abstract

Abstract Mangrove is the name given to a group of trees and shrubs living in salt soils that provide oxygen to the plant through their lenticels in marshy and low-oxygen soils. Mangroves are an important source for a wide range of wood, such as construction, shelters, fences, and non-wood forest products such as honey, sugar, alcohol, vinegar, foliage for fodder and cattle. Various Mangrove species were also identified to treat different ailments, including skin diseases, bleeding, and snake bites, abscesses, orthopedic problems, rheumatism, kidney disorders, diabetes, ulcers, boils, asthma, hepatitis, fever, leprosy, smallpox, dysentery, epilepsy, and hypertension in ethnobotanical surveys in different countries. For instance, in the Comoros and Mauritius Islands, a decoction prepared from the root of a mangrove shrub B. gymnorhiza and five to seven leaves of Piper borbonense boiled in two cups of water, is taken to treat haemorrhage, moreover, also used for diabetes and hypertension. The mangrove plant species are a good source of potential bioactive compounds, such as flavonoids, polyphenols, terpenes, tannins and alkaloids, which exhibit variety of therapeutic properties. Although many mangrove species have been used to treat ailments traditionally by local inhabitants for an extended period, following folk traditions, the number of studied extensively. Due to such rich phytochemical composition, pharmacological studies revealed their effects on various diseases. Among them, antidepressant and antihypertensive properties are also remarkable. Antidepressant effects are explained through mechanisms such as regulating neurotransmitters such as serotonin, dopamine, and norepinephrine, modulation of the HPA axis, and reduction of oxidative stress. Likewise, effects against hypertension are associated with ACE inhibition, improvement of vascular endothelial function, and diuretic effects. The present study will investigate the impact of mangroves on hypertension and depression.

Özet

Mangrov, bataklık ve düşük oksijenli topraklarda yaşayan ve bitkiye lentiselleri aracılığıyla oksijen sağlayan ağaç ve çalı gruplarına verilen isimdir. Mangrovlar, inşaat, barınaklar, çitler gibi çok çeşitli odun ve bal, şeker, alkol, sirke, yem ve sığırlar için yapraklar gibi odun dışı orman ürünleri için önemli bir kaynaktır. Ayrıca, farklı ülkelerde yapılan etnobotanik araştırmalarda, çeşitli mangrov türlerinin deri hastalıkları, kanama, yılan ısırıkları, apseler, ortopedik sorunlar, romatizma, böbrek rahatsızlıkları, diyabet, ülserler, çıbanlar, astım, hepatit, ateş, cüzzam, çiçek hastalığı, dizanteri, epilepsi ve hipertansiyon gibi çeşitli rahatsızlıkların tedavisinde kullanıldığı belirlenmiştir. Örneğin, Komor ve Mauritius adalarında, B. gymnorhiza adlı mangrov çalısının kökünden ve Piper borbonense bitkisinin beş ila yedi yaprağından iki bardak suda kaynatılarak hazırlanan bir dekoksiyon, kanamayı tedavi etmek için kullanılır; ayrıca diyabet ve hipertansiyon tedavisinde de kullanılır. Mangrov bitki türleri, flavonoidler, polifenoller, terpenler, tanenler ve alkaloidler gibi çeşitli terapötik özellikler gösteren potansiyel biyoaktif bileşikler açısından zengin bir kaynaktır. Birçok mangrov türü, halk geleneklerine bağlı olarak uzun süredir yerel halk tarafından çeşitli rahatsızlıkların tedavisinde kullanılmış olsa da, kapsamlı bir şekilde incelenenlerin sayısı azdır. Bu zengin fitokimyasal bileşim nedeniyle, farmakolojik çalışmalar çeşitli hastalıklar üzerindeki etkilerini ortaya koymuştur. Bunlar arasında antidepresan ve antihipertansif özellikleri de dikkat çekicidir. Antidepresan etkiler, serotonin, dopamin ve norepinefrin gibi nörotransmitterlerin düzenlenmesi, HPA ekseninin modülasyonu ve oksidatif stresin azaltılması gibi mekanizmalarla açıklanmaktadır. Benzer şekilde, hipertansiyona karşı etkiler, ACE inhibisyonu, vasküler endotel fonksiyonunun iyileştirilmesi ve diüretik etkilerle ilişkilidir. Bu çalışma, mangrovların hipertansiyon ve depresyon üzerindeki etkisini araştıracaktır.

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Cite This Article

Gündüz, D. A., Koca, U. (2026). Mangrove-Derived Phytochemicals: Therapeutic Role in Depression and Hypertension Management. Current Perspectives on Medicinal and Aromatic Plants, Volume: 9. https://doi.org/10.38093/upmap.1947667c

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