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Journals / ANKEM Dergisi / 2015 / Cilt: 29 - Sayı: 1

Erythromycin Resistance in Streptococcus pyogenes : 2009-2013

Streptococcus pyogenes'te eritromisin direnci: 2009-2013

DENİZ BAHAR AKGÜN KARAPINAR
Meriç YILMAZ
Asuman ÖZBAYRA
Arif KAYGUSUZ
Nezahat GÜRLER
Nuran SALMAN
Pages
26–30
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In these isolates, erythromycin resistance rates over the years were found as 2.8 % (5 out of 174 strains) in 2009, 3.4 % (7 out of 202 strains) in 2010, 2.8 % (8 out of 276 strains) in 2011, 5.1 % (9 out of 176 strains) in 2012 and 3.6 % (12 out of 331 strains) in 2013 respectively.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Streptococcus pyogenes pharyngitis is a common childhood disease.
📊
Key Findings & Data:The aim of this retrospective study is to evaluate proportion of macrolide resistance among pharyngeal isolates of S.pyogenes from pediatric patients between 01.01.2009 and 31.12.2013.
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Conclusion & Impact:In these isolates, erythromycin resistance rates over the years were found as 2.8 % (5 out of 174 strains) in 2009, 3.4 % (7 out of 202 strains) in 2010, 2.8 % (8 out of 276 strains) in 2011, 5.1 % (9 out of 176 strains) in 2012 and 3.6 % (12 out of 331 strains) in 2013 respectively.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:S.pyogenes · eritromisin direnci · S.pyogenes

Abstract

Streptococcus pyogenes pharyngitis is a common childhood disease. The aim of this retrospective study is to evaluate proportion of macrolide resistance among pharyngeal isolates of S.pyogenes from pediatric patients between 01.01.2009 and 31.12.2013. The strains were isolated and identified by conventional methods. The antibiotic susceptibility testing was perfor- med by disc diffusion according to Clinical and Laboratory Standards Institude standards. We studied 12,597 throat cultures and were isolated 1,159 (9.2 %) S.pyogenes in five years. In these isolates, erythromycin resistance rates over the years were found as 2.8 % (5 out of 174 strains) in 2009, 3.4 % (7 out of 202 strains) in 2010, 2.8 % (8 out of 276 strains) in 2011, 5.1 % (9 out of 176 strains) in 2012 and 3.6 % (12 out of 331 strains) in 2013 respectively.

Özet

Çocukluk çağı hastalıklarının en sık görülenlerinden biri Streptococcus pyogenes farenjitidir. Bu çalışmanın amacı, 01.01.2009-31.12.2013 yılları arasında çocuk hastaların boğaz sürüntü örneklerinden izole edilen S.pyogenes’te eritromisin direnç oranlarını retrospektif olarak değerlendirmektir. Suşlar konvansiyonel yöntemler ile izole ve identifiye edilmiştir. Antibiyotik duyarlılık testi Clinical and Laboratory Standards Institude önerilerine göre disk difüzyon yöntemi ile yapılmıştır. Beş sene zaman sürecinde 12,597 boğaz kültürü örneği incelenmiş ve 1,159 (% 9.2) S.pyogenes üremesi saptanmıştır. Bu suşlarda, eritromisin direnç oranları yıllara göre sırasıyla 2009 yılında % 2.8 (n=5/174), 2010 yılında % 3.4 (n=7/202), 2011 yılında % 2.8 (n=8/276), 2012 yılında % 5.1 (n=9/176) ve 2013 yılında % 3.6 (n=12/331) olarak bulunmuştur.

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Cite This Article

KARAPINAR, D. B. A., YILMAZ, M., ÖZBAYRA, A., KAYGUSUZ, A., GÜRLER, N., SALMAN, N. (2015). Erythromycin Resistance in Streptococcus pyogenes : 2009-2013. ANKEM Dergisi, Cilt: 29 - Sayı: 1, 26–30. https://ajindex.com/articles/146177

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References (11)

  1. Bayraktar B, Başarı F, Bulut E. A grubu beta- hemolitik streptokoklarda antibiyotik duyarlılığı ve makrolid direnç fenotipi, ANKEM Derg 2008;22(3):127-31
  2. Berkiten R. Streptococcus pyogenes suşlarında eritromisin direnç fenotipleri ve 1970-2001 yılları arasında Türkiye’de izole edilen suşlarda direnç, ANKEM Derg 2003;17(4):429-34
  3. Berkiten R. Türkiye’de Streptococcus pyogenes’de makrolid direnç fenotipleri ve direnç genleri (1999-2005), ANKEM Derg 2007;21(2):108-12
  4. Bingen E, Bidet P, Mihaila-Amrouche L et al. Emergence of macrolide-resistant Streptococcus pyogenes strains in French children, Antimicrob Agents Chemother 2004;48(9):3559-62.
  5. Bisno AL, Stevens DL. Streptococcus pyogenes, “Mandell GL, Bennett JE, Dolin R (eds). Principles and Practice of Infectious Diseases, 7. baskı “ kita- bında s. 2593-2610, Elsevier, Philadelphia (2010)
  6. Cresti S, Lattanzi M, Zanchi A et al. Resistance determinants and clonal diversity in group a streptococci collected during a period of increa- sing macrolide resistance, Antimicrob Agents Chemother 2002;46(6):1816-22.
  7. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing; Nineteenth-Twenty third Informational Supplement. CLSI Document M100- S19-23. CLSI, Wayne, PA (2009-2013)
  8. Çiftçi E, Doğru Ü, Guriz H, Aysev AD, İnce E. Antibiotic susceptibility of Streptococcus pyoge nes strains isolated from throat cultures of children with tonsillopharyngitis, J Ank Med Sch 2003;25(1):15-20. http://dx.doi.org/10.1501/Jms_0000000039 9. d’Humières C, Cohen R, Levy C et al. Decline in macrolide-resistant Streptococcus pyogenes isola tes from French children, Int J Med Microbiol 2012;302(7-8):300-3.
  9. Eryılmaz M, Akın A, Arıkan Akan Ö. Boğaz kül- türlerinden izole edilen a grubu beta-hemolitik streptokokların antibiyotik duyarlılıkları, ANKEM Derg 2006;20(1):10-2
  10. Green MD, Beall B, Marcon MJ et al. Multicentre surveillance of the prevalence and molecular epi demiology of macrolide resistance among phary- ngeal isolates of group a streptococci in the USA, J Antimicrob Chemother 2006;57(6):1240-3.
  11. Grivea IN, Al-Lahham A, Katopodis GD, Syrogiannopoulos GA, Reinert RR. Resistance to erythromycin and telithromycin in Streptococcus pyogenes isolates obtained between 1999 and 20