Journals / Androloji Bülteni / 2019 / Cilt: 21 - Sayı: 2

Oocyte and sperm mitochondria

Oosit ve sperm mitokondrileri

Pages
62–66
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Data analysis starting from 2018 to backwards were obtained from Pubmed.

📌 3 Key Takeaways

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Objective & Hypothesis:Oocyte and sperm mitochondria also play an important role because of the DNA they possess, besides motility through oxidative phosphorylation and the energy production needed for some functions.
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Key Findings & Data:This is because all mitochondria in the embryo are oocyte originated, mutations in mitochondrial DNA are transmitted maternally to new generations, and cause maternally inherited mitochondrial diseases.
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Conclusion & Impact:Data analysis starting from 2018 to backwards were obtained from Pubmed.
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Oocyte and sperm mitochondria also play an important role because of the DNA they possess, besides motility through oxidative phosphorylation and the energy production needed for some functions. This is because all mitochondria in the embryo are oocyte originated, mutations in mitochondrial DNA are transmitted maternally to new generations, and cause maternally inherited mitochondrial diseases. Sperm mitochondria undergoes elimination during spermatogenesis or in the early stages of embryogenesis through variable mechanisms between species, and existence of mitochondria can’t keep up. The aim of this study is to investigate the role of oocyte and sperm mitochondria on fertilization. Data analysis starting from 2018 to backwards were obtained from Pubmed.

Özet

Oosit ve sperm mitokondrilerinin oksidatif fosforilasyon yoluyla moti- lite ve bazı fonksiyonlar için ihtiyaç duyulan enerjiyi üretmeleri dışın- da, sahip oldukları DNA nedeniyle rolleri oldukça önemlidir. Bunun nedeni, embriyodaki bütün mitokondrilerin oosit kökenli olmasından dolayı, mitokondri DNA’larındaki mutasyonların maternal olarak yeni kuşaklara aktarılması ve mitokondriyal geçişli hastalıklara sebep olması- dır. Sperm mitokondrileri ise, türler arasında farklı mekanizmalar aracı- lığıyla spermatogenez esnasında veya embriyogenezin erken evrelerinde eliminasyona uğrar ve varlıklarını sürdüremezler. Bu çalışmadaki amacı- mız, oosit ve sperm mitokondrilerinin fertilizasyon üzerindeki rollerini araştırmaktır. Veriler, 2018 yılı itibarıyla Pubmed’den taranarak elde edilmiştir.

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Cite This Article

TAN, S., ÖZER, M. C., ÇİL, N., ÜNAL, M. S. (2019). Oocyte and sperm mitochondria. Androloji Bülteni, Cilt: 21 - Sayı: 2, 62–66. https://ajindex.com/articles/144616

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