Journals / 7tepe Klinik / 2019 / Cilt: 15 - Sayı: 2

Platelet rich fibrin application in apical resection operations: Case series

Apikal rezeksiyon operasyonlarında trombositten zengin fibrin uygulaması: Olgu serisi

Pages
253–257
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to the clinical and radiographic results of the patients at periodic controls, PRF appeared to be effective in the regeneration of bone gap space providing an alternative to conventional surgical treatment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:During the healing of bone cavities formed after apical resection, the desired results are not always obtained.
📊
Key Findings & Data:For this reason, regenerative treatments have begun to be applied in apical resection cavities.
💡
Conclusion & Impact:According to the clinical and radiographic results of the patients at periodic controls, PRF appeared to be effective in the regeneration of bone gap space providing an alternative to conventional surgical treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

During the healing of bone cavities formed after apical resection, the desired results are not always obtained. For this reason, regenerative treatments have begun to be applied in apical resection cavities. Platelet-rich fibrin (PRF) is a second-generation platelet product derived from the blood of the same individual and used to obtain a membrane rich in plateletes and growth factors. In this case series, clinical and radiographic results of PRF placement onto the operation area after apical resection were presented. All the necrotic and inflamed tissue were removed from the periapical region during the surgical procedure of three patients referred to the endodontic clinic with indication of apical resection. Following application of PRF to the defect area which is prepared by centrifugation of the venous blood taken from the patients, wound site was sutured. According to the clinical and radiographic results of the patients at periodic controls, PRF appeared to be effective in the regeneration of bone gap space providing an alternative to conventional surgical treatment.

Özet

Apikal rezeksiyon sonrası oluşturulan kemik kavitelerinin iyileşmeleri sırasında her zaman istenilen sonuçlar elde edilememektedir. Bu nedenle apikal rezeksiyon kavitelerinde rejeneratif tedaviler uygulanmaya başlanmıştır. Trombositten zengin fibrin (TZF) bireyin kanının santrifüj edilerek trombosit ve büyüme faktörlerinden zengin bir membran elde etmeyi sağlayan ikinci nesil trombosit ürünüdür. Bu vaka serisinde apikal rezeksiyon işlemi sonrası operasyon bölgesine yerleştirilen TZF’nin klinik ve radyografik olarak sonuçları sunulmuştur. Endodonti kliniğinden apikal rezeksiyon endikasyonu ile sevk edilen 3 hastaya cerrahi işlem sırasında periapikaldeki tüm nekrotik ve iltihaplı dokunun küretajı yapılmış ve defekt bölgesine hastalardan alınan venöz kanın santrifüj edilmesiyle hazırlanan TZF uygulanarak yara yeri süture edilmiştir. Hastaların periyodik kontrollerindeki klinik ve radyografik sonuçlarına göre; TZF’nin kemik kavitesi boşluğunun rejenerasyonunda etkili olduğu ve konvansiyonel cerrahi tedaviye alternatif bir rejeneratif tedavi şekli olabileceği kanısındayız.

🔖

Cite This Article

YILDIRIM, A., TOKER, H., KANMAZ, F., ALTUNBAŞ, N. (2019). Platelet rich fibrin application in apical resection operations: Case series. 7tepe Klinik, Cilt: 15 - Sayı: 2, 253–257. https://ajindex.com/articles/144195

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Sjögren U, Hägglund B, Sundqvist G, Wing K. Factors affecting the long term results of endodontic treatment. J Endod 1990; 16:498-504
  2. Navarre SW, Steiman HR. Root-end fracture during retropreparation: A comparison between zirconium nitride-coated and stainless steel microsurgical ultrasonic instruments. J Endod 2002; 28:330-332
  3. Brown, D C. Advances in Endodontik Surgery. Part I Dental Update, September 1995 4. Arisu HD, Sadik B, Bala O, Turkoz E. Computer-assisted evaluation of micro leakage after apical resection with laser and conventional techniques. Lasers Med Sci 2008; 23:415-420
  4. Balcı H, Toker H. Trombositten zengin fibrin: Özellikleri ve diş hekimliğinde kullanımı. Acta Odontologica Turcica, 2012; 29(3): 183 6. Choukroun J, Diss A, Simonpieri A, Girard MO, Schoeffler C, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate, Part IV: Clinical effects on tissue healing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 101: E56-60 7. Choukroun J, Diss A, Simonpieri A, Girard MO, Schoeffler C, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part V: Histologic evaluations of PRF effects on bone allograft maturation in sinus lift. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 101: 299- 303 8. Dohan DM, Choukroun J, DissA, Dohan SL, DohanAJ. Platelet-rich fibrin (PRF): a second generation platelet concentrate. Part III: leucocyte activation: a new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 101: e51-55
  5. Van Hinsbergh VW, Collen A, Koolwijk P. Role of fibrin matrix in angiogenesis. Ann N YAcad Sci 2001; 936:426- 437
  6. Anitua E, Andia I, Ardanza B, Nurden P, Nurden AT. Autologousplatelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004; 91(1):4-15
  7. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, et al. Platelet-rich fibrin(PRF): A second-generation platelet concentrate. Part II: Plateletrelated biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Oral Endod 2006; 101:45-50
  8. Nurden AT. Platelets, inflammation and tissue regeneration. Thromb Haemost 2011; 105(1):13-33
  9. Pierce GF, Mustoe TA, Altrock BW, Deuel TF, Thomason A. Role of platelet-derived growth factor in wound healing. J Cell Biochem. 1991; 45:319-326 14. Bolander ME. Regulation of fracture repair by growth factors. Proc Soc Exp Biol Med. 1992; 200: 165-170 15. Sharma A, Pradeep AR. Autologous Platelet-Rich Fibri