Journals / Türk Pediatri Arşivi / 2026 / Cilt: 28 Sayı: 1

Physiopathology and Treatment in Meningococcal Sepsis

Meningokok Sepsisinde Fizyopatoloji ve Tedavi

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Publication Date
1993-03-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Mortality in meningcoccal sepsis is still very high despite appropriate chemotherapy and advanced intensive care facilities Cytokines and mediators secreted after bacterial lipopolysaccaharide stimulation are responsible for hemodynamic and metabolic disorders The basic therapeutic principles are administration of antibiotics and intravenous fluids New therapeutic measures such as plasmapheresis leucopheresis and administration of anticytokines antibodies may prove effective in the future Key words: Meningococcal Sepsis Physiopathology Treatment

📌 3 Key Takeaways

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Objective & Hypothesis:Mortality in meningcoccal sepsis is still very high despite appropriate chemotherapy and advanced intensive care facilities Cytokines and mediators secreted after bacterial lipopolysaccaharide stimulation are responsible for hemodynamic and metabolic disorders The basic therapeutic principles are administration of antibiotics and intravenous fluids New therapeutic measures such as plasmapheresis leucopheresis and administration of anticytokines antibodies may prove effective in the future Key words: Meningococcal Sepsis Physiopathology Treatment
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Key Findings & Data:Mortality in meningcoccal sepsis is still very high despite appropriate chemotherapy and advanced intensive care facilities Cytokines and mediators secreted after bacterial lipopolysaccaharide stimulation are responsible for hemodynamic and metabolic disorders The basic therapeutic principles are administration of antibiotics and intravenous fluids New therapeutic measures such as plasmapheresis leucopheresis and administration of anticytokines antibodies may prove effective in the future Key words: Meningococcal Sepsis Physiopathology Treatment
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Conclusion & Impact:Mortality in meningcoccal sepsis is still very high despite appropriate chemotherapy and advanced intensive care facilities Cytokines and mediators secreted after bacterial lipopolysaccaharide stimulation are responsible for hemodynamic and metabolic disorders The basic therapeutic principles are administration of antibiotics and intravenous fluids New therapeutic measures such as plasmapheresis leucopheresis and administration of anticytokines antibodies may prove effective in the future Key words: Meningococcal Sepsis Physiopathology Treatment
🔬Design:Makale
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Mortality in meningcoccal sepsis is still very high despite appropriate chemotherapy and advanced intensive care facilities Cytokines and mediators secreted after bacterial lipopolysaccaharide stimulation are responsible for hemodynamic and metabolic disorders The basic therapeutic principles are administration of antibiotics and intravenous fluids New therapeutic measures such as plasmapheresis leucopheresis and administration of anticytokines antibodies may prove effective in the future Key words: Meningococcal Sepsis Physiopathology Treatment

Özet

SummaryMortality in meningcoccal sepsis is still very high despite appropriate chemotherapy and advanced intensive care facilities Cytokines and mediators secreted after bacterial lipopolysaccaharide stimulation are responsible for hemodynamic and metabolic disorders The basic therapeutic principles are administration of antibiotics and intravenous fluids New therapeutic measures such as plasmapheresis leucopheresis and administration of anticytokines antibodies may prove effective in the future Key words: Meningococcal Sepsis Physiopathology Treatment

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Cite This Article

Tüysüz, B., Özlü, İ. (1993). Physiopathology and Treatment in Meningococcal Sepsis. Türk Pediatri Arşivi, Cilt: 28 Sayı: 1. https://ajindex.com/articles/1438113