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Journals / Acta Medica / 2018 / Cilt: 49 - Sayı: 2

Determining Thyroid Disorders in Younger Age Group (pre-Pubertal, Peri-Pubertal & Pubertal) Individuals: An Observational Study

Madeeha SUBHAN
Waleed SADIQ
Sanniyah SUBHAN
Pages
15–30
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This disease can’t be prevented but early diagnosis can reduce complications that can be life threatening.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Determine thyroid disorders in younger age group (pre-Pubertal, Peri- Pubertal & Pubertal) individuals.
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Key Findings & Data:Method: : Blood samples were obtained from patients advised assessment of thyroid hormone levels, during an eight month period spanning from May to December 2010.
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Conclusion & Impact:This disease can’t be prevented but early diagnosis can reduce complications that can be life threatening.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Özet

Objective: Determine thyroid disorders in younger age group (pre-Pubertal, Peri- Pubertal & Pubertal) individuals. Method: : Blood samples were obtained from patients advised assessment of thyroid hormone levels, during an eight month period spanning from May to December 2010. Only those subjects were included for this study, which had been evaluated for all three parameters of thyroid function (T3, T4, and TSH). The assessment of free frac- tion of T3 and T4 was carried out keeping in view their diagnostic advantage over the total hormones. Serum thyroid hormones from patients’ serum were estimated by using the Roche Elecsys 2010 immunoassay analyzer installed at the Reproductive Physiology department of the National Institute of` Health, Islamabad. It is an auto- mated analyzer with inbuilt software system, and is based on electrochemiluminis- cence. Data of all subjects were expressed as Mean±SD, and compared statistically by correlation, and student’s “t” test. Result: Serum samples of 12 pre-pubertal (6-9 years) subjects were evaluated for their thyroid functions. Results of 8 subjects showed normal thyroid hormone levels, and 3 different patterns of abnormal activity were observed. In peri-pubertal subjects (10- 15 years) Serum of 28 (19 female and 9 male) subjects in this age group (10-15 years) were evaluated for thyroid function, and 19 subjects showed normal results constitut- ing 14 female and 5 males. In pubertal subjects serum samples of 37 individuals of this age group (16-19 years) were evaluated for thyroid function. Out of which 25 individ- uals showed normal thyroid activity, and FT4 and TSH had significant (p<0.05) nega- tive correlation (r= -0.3799) with them. Conclusion: About 200 million people in the world have some form of thyroid dis- ease. Thyroid disorders are common endocrine disorders encountered in Pakistan. This disease can’t be prevented but early diagnosis can reduce complications that can be life threatening.

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Cite This Article

SUBHAN, M., SADIQ, W., SUBHAN, S. (2018). Determining Thyroid Disorders in Younger Age Group (pre-Pubertal, Peri-Pubertal & Pubertal) Individuals: An Observational Study. Acta Medica, Cilt: 49 - Sayı: 2, 15–30. https://ajindex.com/articles/143686

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References (8)

  1. Lemaire D. Thyroid anatomy. https://reference.medscape.com/ article/835535-overview (accessed May 2017) Akhtar P, ur-Rehman K, Orfi SD, et al. Assessment of iodine levels in the Pakistani diet. Nutrition 2004; 20: 783–87. doi.org/10.1016/j. nut.2004.05.019 Knudsen, Laurberg N P, Lonc B, et al. Small differences in thy-roid function may be important for body mass index and the oc-currence of obesity in the population. J. Clin. Endocriol. Mctab. 2005; 90: 4019– 4024. https://doi.org/10.1210/jc.2004-2225. 2005;
  2. Triggiani V, Tafaro E, Giagulli V A, et al. Role of iodine, seleni-um and other micronutrients in thyroid function and disorders. Endocr Metab Immune Disord Drug Targets. 2009; 9(3): 277-94.
  3. Ciloglu F, Peker I, Pehlivan A, et al. Exercise intensity and its effects on thyroid hormones. Neuroendocrinol Lett. 2005; 26: 830–834. 2005;
  4. Scorza F A, Arida R M, Cysneiros R M, et al. Hyperthyroidism and sudden unexpected death in epilepsy. Med Hypotheses. R, Machado H. and Subclinical, Cavalheiro E.A. (ed): 2010. 74: 692– 4. https://doi.org/10.1016/j.mehy. 2009.10.045 Negro R, Soldin OP, Obregon MJ, et al. Hypothyroxinemia and-pregnancy. Endocr Pract 2011; 17: 422–29. Millichap JG. Etiologic classification of attention-deficit/hy-peractivitydisorder. Pediatrics 2008; 121: 358– 65. https://doi. org/10.1542/peds.2007-1332
  5. Molashenko NV, Sviridenko NI, Platonova NM. The specific fea-turesof thyrotoxicosis and euthyroid hyperthyroxinemia devel-oped due to the use of cordarone. Klin Med (Mosk) 2004; 82: 35–9.
  6. Sanger N, Stahlberg S, Manthey T. Effects of an oral contracep-tive containing 30 mcg ethinyl estradiol and 2 mg dienogest on thyroid hormones and androgen parameters:conventional vs. extended-cycle use. Contraception 2008; 77: 420–25. https://doi. org/10.1016/j.contraception. Azim W, Ali A, Azim S. Rational thyroid screening by thyroid stim-ulating hormone assay. Biomedical. 2008; 24: 89–91. Shamon M.An overview of thyroid disease. https://www.very-wellhealth.com/thyroid- 4014636 (accessed May 2017) Cooper D S. Subclinical Hypothyroidism. N Eng J Med. 2000, 345:260–265. 10.1056/NEJM200107263450406 M, Shamon. New guideline say million More at Thyroid Risk, Disease and Condition (updated June) 03, 2009; retrieved 20/04/2011.
  7. Niafar M, Najafipour F, Bahram A. Subclinical Thyroid Disorders In Postmenopausal Women of Iran. JCDR 2009; 3: 1853–58.
  8. Rubina M, Rizvi SSR, Huda S, et al. Spectrum of Thyroid Diseases,An Experience in the Tertiary care and Teaching Hospital