Journals / Türkiye Çocuk Hastalıkları Dergisi / 2026 / Cilt: 10 Sayı: 3

Primary Cutaneous T-Cell Lymphoma in Children: Report of Two Cases

Çocuklarda Primer Kutanoz T- Hücreli Lenfoma: İki Olgu Sunumu

Derya Özyörük(Ankara Children’s Hematology and Oncology Hospital, Department of Pediatrics, Division of Pediatric Oncology, Ankara, Turkey)
Suna Emir(Ankara Children’s Hematology and Oncology Hospital, Department of Pediatrics, Division of Pediatric Oncology, Ankara, Turkey)
Hacı Ahmet Demir(Ankara Children’s Hematology and Oncology Hospital, Department of Pediatrics, Division of Pediatric Oncology, Ankara, Turkey)
Esra Karakuş(Ankara Children’s Hematology and Oncology Hospital, Department of Pediatrics, Division of Pediatric Oncology, Ankara, Turkey)
Cengiz Bayram(Ankara Children’s Hematology and Oncology Hospital, Department of Pediatrics, Division of Pediatric Oncology, Ankara, Turkey)
Bahattin Tunç(Ankara Children’s Hematology and Oncology Hospital, Department of Pediatrics, Division of Pediatric Oncology, Ankara, Turkey)
Pages
213–215
Publication Date
2016-08-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After a biopsy and metastatic work up, one patient was diagnosed as primary cutaneous peripheral T-cell lymphoma, unspecified, and the other as primary cutaneous CD30 positive ALK negative anaplastic large cell lymphoma

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Primary cutaneous lymphomas in children are rare and constitute a heterogeneous group in regard to histological subtype, clinical course and prognosis.
📊
Key Findings & Data:Here, we present the clinical characteristics and outcomes of two children with primary cutaneous lymphoma with different histopathologic subtypes.
💡
Conclusion & Impact:After a biopsy and metastatic work up, one patient was diagnosed as primary cutaneous peripheral T-cell lymphoma, unspecified, and the other as primary cutaneous CD30 positive ALK negative anaplastic large cell lymphoma
🔬Design:Makale
📍Scope:Comprehensive Sample
⚙️Variables:Kutanöz anaplastik büyük hücreli lenfoma · Periferik T hücreli lenfoma · Primer kutanöz lenfoma

Abstract

Primary cutaneous lymphomas in children are rare and constitute a heterogeneous group in regard to histological subtype, clinical course and prognosis. Here, we present the clinical characteristics and outcomes of two children with primary cutaneous lymphoma with different histopathologic subtypes. They had been diagnosed as a skin abscess initially but had not responded to systemic antibiotherapy and dressing. After a biopsy and metastatic work up, one patient was diagnosed as primary cutaneous peripheral T-cell lymphoma, unspecified, and the other as primary cutaneous CD30 positive ALK negative anaplastic large cell lymphoma

Özet

Primer kutanöz lenfomalar çocukluk çağında çok nadir olup histolojik alt tip, klinik seyir ve prognoz bakımından farklılık gösterirler. Burada farklı histopatolojik özelliklere sahip iki primer kutanöz lenfoma olgusu sunulmaktadır. Her iki olgunun ortak özelliği sistemik antibiyotik ve pansuman tedavilerine yanıt vermeyen cilt apsesi ile başvurmuş olmalarıydı. Biyopsi ve evreleme çalışmalarından sonra bir olgu primer kutanöz periferik T hücreli lenfoma, tanımlanamayan, diğer olgu ise primer kutanöz CD30 pozitif ALK negatif anaplastik büyük hücreli lenfoma tanısı aldı.

🔖

Cite This Article

Özyörük, D., Emir, S., Demir, H. A., Karakuş, E., Bayram, C., Tunç, B. (2016). Primary Cutaneous T-Cell Lymphoma in Children: Report of Two Cases. Türkiye Çocuk Hastalıkları Dergisi, Cilt: 10 Sayı: 3, 213–215. https://ajindex.com/articles/1435763

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References (11)

  1. Fink-Puches R, Chott A, Ardigo M, et al. The spectrum of cutaneous lymphomas in patients less than 20 years of age. Pediatr Dermatol 2004;21:525-33.
  2. Willemze R, Hodak E, Zinzani PL, Specht L, Ladetto M. Primary cutaneous lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2013;(24 Suppl 6): 149-54.
  3. Querfeld C, Guitart J, Kuzel TM, Rosen ST. Primary cutaneous lymphomas: A review with current treatment options. Blood Rev 2003;17:131-42.
  4. Oliveira MC, Pereira LB, Rodrigues PC, Sampaio KC, Oliveira BM, Viana MB. Initial cutaneous manifestation of lymphomas in children. An Bras Dermatol 2011;86:799-802.
  5. Windsor R, Stiller C, Webb D. Peripheral T-cell lymphoma in childhood: Population-based experience in the United Kingdom over 20 years. Pediatr Blood Cancer 2008;50:784-7.
  6. Hung TY, Lin YC, Sun HL, Liu MC. Primary cutaneous anaplastic large cell lymphoma in a young child. Eur J Pediatr 2008;167: 111-3.
  7. Bekkenk MW, Vermeer MH, Jansen PM, van Marion AM, Canninga-van Dijk MR, Kluin PM, et al. Peripheral T-cell lympho- mas unspecified presenting in the skin: Analysis of prognostic fac- tors in a group of 82 patients. Blood 2003;102:2213-9.
  8. Kumar S, Pittaluga S, Raffeld M, Guerrera M, Seibel NL, Jaffe ES. Primary cutaneous CD30-positive anaplastic large cell lymphoma in childhood: Report of 4 cases and review of the literature. Pediatr Dev Pathol 2005;8:52-60.
  9. Ju E, Adigun C, Dunphy C, Gold S, Morrell DS. Anaplastic large cell lymphoma: An unusual presentation in a 7-year-old girl. Pediatr Dermatol 2012;29:498-503.
  10. Tomaszewski MM, Moad JC, Lupton GP. Primary cutaneous Ki- 1(CD30) positive anaplastic large cell lymphoma in childhood. J Am Acad Dermatol 1999;40:857-61.
  11. Daar G, Küpeli S, Yalçın B, Kesik V, Orhan D, Buyukpamukçu M. Primary cutaneous anaplastic large cell lymphoma. Pediatr Hematol and Oncol 2010: 27:558–63.