AI Summary & Key Takeaways
AI InsightIn chronic lymphocytic leukemia, CAT activity was found to be significantly decreased and in chronic myeloid leukemia, it was found to be in normal ranges of activity although in both types of chronic leukemia, the activities were lower than the normal control group with respect to averages.
📌 3 Key Takeaways
Abstract
Catalase (CAT) enzyme activities were measured in erythrocytes isolated from untreated patients with chronic leukemia, by using Aebi's method. In chronic lymphocytic leukemia, CAT activity was found to be significantly decreased and in chronic myeloid leukemia, it was found to be in normal ranges of activity although in both types of chronic leukemia, the activities were lower than the normal control group with respect to averages. These results suggest that catalase as an erythrocyte antioxidant enzyme may play an important role in chronic leukemias. [Journal of Turgut ÖzalMedical Center 1997;4(1):7-9] KeyWords : Catalase, chronic leukemia, erythrocyte
Özet
Kronik lösemili hastalarda, eritrosit içi katalaz aktiviteleri, henüz tedaviye başlanmadan önce, Aebi'nin yöntemi kullanılarak tayin edildi. Her iki tip kronik lösemide de katalaz aktiviteleri, ortalamalara bakıldığında normal kontrol grubundan daha düşük olduğu halde, sadece kronik lenfositik lösemide istatistik olarak anlamlı düşüklük saptandı. Bu bulgular, katalazın eritrosit içi bir antioksidan enzim olarak kronik lösemilerde önemli bir role sahip olabileceğini düşündürmektedir. [Turgut Özal Tıp Merkezi Dergisi 1997;4(1):7-9] Anahtar kelimeler: Katalaz, kronik lösemi, eritrosit