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Journals / Turgut Özal Tıp Merkezi Dergisi / 2026 / Cilt: 16 Sayı: 1

The Importance of Regional Cytotoxic Infusion in Treatment of Colorectal Hepatic Metastasis

Kolorektal Hepatik Metastazların Tedavisinde Sitotoksik Regional İnfüzyonun Yeri

Abuzer Dirican
Sezai Yılmaz
Pages
57–61
Publication Date
2009-02-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Key words: Colorectal Hepatic Metastasis, Regional Hepatic Chemotherapy

📌 3 Key Takeaways

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Objective & Hypothesis:The goals of regional cytotoxic hepatic infusion are to maximize the concentration of chemotherapeutic drugs reaching malignant tumors, to increase tumor cells' cytotoxic drug uptake and to minimize systemic toxicity.
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Key Findings & Data:In this paper we have purposed to emphasis the importance and current way of regional hepatic infusion chemotherapy.
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Conclusion & Impact:Key words: Colorectal Hepatic Metastasis, Regional Hepatic Chemotherapy
🔬Design:Makale
📍Scope:Comprehensive Sample
⚙️Variables:Kolorektal Hepatik Metastazlar · Regional Hepatik Kemoterapi · Colorectal Hepatic Metastasis

Abstract

The goals of regional cytotoxic hepatic infusion are to maximize the concentration of chemotherapeutic drugs reaching malignant tumors, to increase tumor cells' cytotoxic drug uptake and to minimize systemic toxicity. In this paper we have purposed to emphasis the importance and current way of regional hepatic infusion chemotherapy. While some investigators preferred the portal vein for regional chemotherapy in the past, currently, hepatic artery chemotherapy more frequently prefer for regional infusion chemotherapy. Key words: Colorectal Hepatic Metastasis, Regional Hepatic Chemotherapy

Özet

Sitotoksik regional hepatik infüzyonun amaçları; malign tümöre ulaşan kemoterapötik konsantrasyonu en yüksek seviyelere çıkarmak, tümör hücrelerinin sitotoksik ajan uptake'ini arttırmak ve sistemik toksisiteyi azaltmaktır. Bu makalede regional hepatik infüzyonal kemoterapinin önemini ve en uygun infüzyon yollarını vurgulamayı amaçladık. Daha önceleri portal ven de regional infüzyon kemoterapisi için kullanılmış olmakla beraber, bugün daha çok hepatik arter tercih edilmektedir. Anahtar kelimeler: Kolorektal Hepatik Metastazlar, Regional Hepatik Kemoterapi

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Cite This Article

Dirican, A., Yılmaz, S. (2009). The Importance of Regional Cytotoxic Infusion in Treatment of Colorectal Hepatic Metastasis. Turgut Özal Tıp Merkezi Dergisi, Cilt: 16 Sayı: 1, 57–61. https://ajindex.com/articles/1433968

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