Journals / İstanbul Tıp Fakültesi Dergisi / 2021 / Cilt: 84 - Sayı: 2

CLINICOPATHOLOGIC FEATURES OF PROBABLY MALIGNANT ADNEXAL MASSES WITHOUT SIGNS OF ASCITES AND CARCINOMATOSIS

ASİT VE KARSİNOMATOZİS BULGUSU OLMAYAN YÜKSEK OLASILIKLA MALİGN ADNEKSİYEL KİTLELERİN KLİNİK VE PATOLOJİK ÖZELLİKLERİ

Pages
192–196
Publication Date
2021-04-25
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Patients with a suspicious adnexal mass, even if ascites or carcinomatosis are not existing, have a high rate of malignancy and should be managed considering this risk.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Our objective was to assess the patients who have probable early stage ovarian cancer.
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Key Findings & Data:Materal and Method: Between 2010-2018, 208 patients with isolated adnexal masses who underwent surgery due to presumed malignancy were analyzed.
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Conclusion & Impact:Conclusion: Patients with a suspicious adnexal mass, even if ascites or carcinomatosis are not existing, have a high rate of malignancy and should be managed considering this risk.
🔬Design:Research Article
📍Scope:2010-2018 Verileri
⚙️Variables:Adneksiyal kitle · over kanseri · malignite

Abstract

Objective: Our objective was to assess the patients who have probable early stage ovarian cancer. Materal and Method: Between 2010-2018, 208 patients with isolated adnexal masses who underwent surgery due to presumed malignancy were analyzed. We excluded patients with radiologic evidence of ascites and tumour implants. Results: According to the final pathology reports, 52 (25%) of 208 patients had benign tumours, 46 (22%) were borderline, and 110 (53%) patients’ tumours were malignant. The most unexpected benign tumours were serous cystadenofibroma. Of the malignant tumours, 3 were uterine sarcomas, 8 were metastatic ovarian tumours (all gastrointestinal origin), and 99 were primary ovarian cancers. Seventy-six of 99 primary ovarian cancers were epithelial and 23 were nonepithelial. The most common histologic types were respectively serous and endometrioid adenocarcinoma. Seventy-six percent of primary ovarian cancers were early stage (stage 1-2) and 24% were advanced stage (stage 3-4). Conclusion: Patients with a suspicious adnexal mass, even if ascites or carcinomatosis are not existing, have a high rate of malignancy and should be managed considering this risk.

Özet

Amaç: Amacımız muhtemelen malign adneksiyel kitlesi olan hastaları değerlendirmektir. Gereç ve Yöntem: 2010-2018 yılları arasında salt adneksiyal kitlesi olan ve malignite riski nedeniyle ameliyat yapılan 208 hastanın medikal verileri incelendi. Radyolojik olarak asit ve tümöral implant bulgusu olan hastalar çalışma dışı bırakıldı. Bulgular: Nihai patoloji raporlarına göre 208 hastanın 52'si (%25) benign, 46'sı (%22) borderline ve 110'u (%53) malign idi. En beklenmedik benign tümör seröz kistadenofibrom idi. Malign tümörlerin 3'ü uterin sarkom, 8'i metastatik over kanseri (tümü gastrointestinal kaynaklı), 99'u primer over kanseri idi. Doksan dokuz primer over kanserinin 76'sı epitelyal, 23'ü nonepitelyal idi. En sık görülen histolojik tipler sırasıyla, seröz ve endometrioid adenokarsinom idi. Primer over kanserlerinin %76'sı erken evrede (evre 1-2), %24'ü ileri evrede (evre 3-4) idi. Sonuç: Şüpheli adneksiyal kitlesi olan hastalarda, asit veya karsinomatosiz bulgusu olmasa bile, yüksek malignite riski mevcuttur ve bu risk göz önünde bulundurularak yönetilmelidir.

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Cite This Article

ÇELİKSOY, H. Y., SÖZEN, H., BAKTIROĞLU, H. M., TOPUZ, S., SALİHOĞLU, Y. (2021). CLINICOPATHOLOGIC FEATURES OF PROBABLY MALIGNANT ADNEXAL MASSES WITHOUT SIGNS OF ASCITES AND CARCINOMATOSIS. İstanbul Tıp Fakültesi Dergisi, Cilt: 84 - Sayı: 2, 192–196. https://ajindex.com/articles/142515

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References (2)

  1. Noone AM, Howlader N, Krapcho M, Miller D, Brest A, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2015, National Cancer Institute
  2. Van Calster B, Van Hoorde K, Valentin L, Testa AC, Fischerova D, Van Holsbeke C, Savelli L, Franchi D, Epstein E, Kaijser J, Van Belle V, Czekierdowski A, Guerriero S, Fruscio R, Lanzani C, Scala F, Bourne T, Timmerman D, International Ovarian Tumour Analysis Group Evaluating the risk of ovarian cancer before surgery using the ADNEX model to differentiate between benign, borderline, early and advanced stage invasive, and secondary metastatic tumours: prospective multicentre diagnostic study. BMJ. 2014;349:g5920. [CrossRef] 3. Bristow RE, Berek JS. Surgery for ovarian cancer: how to improve survival. Lancet 2006;367:1558–60. [CrossRef] 4. Greving JP, Vernooij F, Heintz APM, van der Graaf Y, Buskens E. Is centralization of ovarian cancer care warranted? A cost‐effectiveness analysis Gynecol Oncol 2009;113:68–74. [CrossRef] 5. Vergote I, De Brabanter J, Fyles A, Bertelsen K, Einhorn N, Sevelda P, et al. Prognostic importance of degree of differentiation and cyst rupture in stage I invasive epithelial ovarian carcinoma. Lancet 2001;357:176–82. [CrossRef] 6. Demir RH, Marchand GJ. Adnexal Masses Suspected to Be Benign Treated with Laparoscopy. JSLS. 2012;16(1):71–84. [CrossRef] 7. American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins— Gynecology. Gynecologists’ Committee on Practice, Practice Bulletin No. 174: evaluation and management of adnexal masses. Obstet Gynecol 2016;128:e210–26. [CrossRef] 8. National Institutes of Health Consensus Development Conference Statement. Ovarian cancer: screening, treatment, and follow-up. Gynecol Oncol 1994; 55:S4. [CrossRef] 9. McDonald JM, Doran S, DeSimone CP, Ueland FR, DePriest PD, Ware RA, Saunders BA, Pavlik EJ, Goodrich S, Kryscio RJ, van Nagell JR Jr. Predicting risk of malignancy in adnexal masses. Obstet Gynecol. 2010 Apr;115(4):687-94. [CrossRef] 10. Heintz AP, Odicino F, Maisonneuve P, et al. Carcinoma of the fallopian tube. Int J Gynaecol Obstet 2006; 95:S145 [CrossRef] 11. Dodge JE, Covens AL, Lacchetti C, et al. Management of a suspicious adnexal mass: a clinical practice guideline. Curr Oncol 2012;19:E244–57. [CrossRef] 12. Engelen MJ, Kos HE, Willemse PH, Aalders JG, de Vries EG, Schaapveld M, et al. Surgery by consultant gynecologic oncologists improves survival in p