Journals / Journal of Experimental and Clinical Medicine / 2026 / Volume: 41 Issue: 3

Association between COVID-19 vaccination during pregnancy and SGA in a rural area

Pakize Özge Karkın(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ İSTANBUL KANUNİ SULTAN SÜLEYMAN EĞİTİM VE ARAŞTIRMA HASTANESİ)0000-0003-3296-8887
Gözde Sezer(MANİSA CELÂL BAYAR ÜNİVERSİTESİ, MANİSA SAĞLIK YÜKSEKOKULU)0000-0003-2961-9221
Pages
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Publication Date
2024-09-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Pregnant women are skeptical about the COVID-19 vaccine, but inactivated and mRNA COVID-19 vaccine administration during pregnancy seems safe in terms of SGA incidence.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Vaccines were the most crucial factor in ending the COVID-19 pandemic.
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Key Findings & Data:Different types of COVID-19 vaccines were administered worldwide to all ages, including pregnant women.
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Conclusion & Impact:Pregnant women are skeptical about the COVID-19 vaccine, but inactivated and mRNA COVID-19 vaccine administration during pregnancy seems safe in terms of SGA incidence.
🔬Design:Research Article
📍Scope:2021 Verileri
⚙️Variables:COVID-19 · small for gestational age · vaccination

Abstract

Vaccines were the most crucial factor in ending the COVID-19 pandemic. Different types of COVID-19 vaccines were administered worldwide to all ages, including pregnant women. This study aimed to evaluate if different types of COVID-19 vaccines applied during pregnancy affect the "Small for Gestational Age" (SGA) incidence in a rural area of Turkey. A retrospective cohort study was performed with 146 completed pregnancies between 2021 and 2022. The health repository was scanned to obtain COVID-19 vaccination status during pregnancy, the type of COVID-19 vaccine administered and fetal birth weight. The presence of SGA was detected by using a gender-specific Fenton growth chart in newborns. We investigated the incidence of SGA for the whole study population and vaccinated group, as well as the types and trimesters of COVID-19 vaccination during pregnancy. There was no statistical significance between all pregnancies and vaccinated women during pregnancy in terms of SGA incidence (p>0.05). Either COVID-19 vaccination during pregnancy or type of COVID-19 vaccines or trimester of application did not statistically change the incidence of SGA (p>0.05). Pregnant women are skeptical about the COVID-19 vaccine, but inactivated and mRNA COVID-19 vaccine administration during pregnancy seems safe in terms of SGA incidence.

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Cite This Article

Karkın, P. Ö., Sezer, G. (2024). Association between COVID-19 vaccination during pregnancy and SGA in a rural area. Journal of Experimental and Clinical Medicine, Volume: 41 Issue: 3. https://ajindex.com/articles/1422651

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References (22)

  1. Altın Z. Covid-19 pandemisinde yaşlılar. Tepecik Eğit. ve Araşt. Hast. Dergisi. 2020;30:49-57.
  2. Dsouza DD, Quadros S, Hyderabadwala ZJ, Mamun MA. Aggregated COVID-19 suicide incidences in India: Fear of COVID-19 infection is the prominent causative factor. Psychiatry Res. 2020;290:113145.
  3. NASPAG Position Statement on COVID-19 Vaccines and Gynecologic Concerns in Adolescents and Young Adults. J Pediatr Adolesc Gynecol. 2021;34(4):439-440.
  4. Jing Y, Run-Qian L, Hao-Ran W, Hao-Ran C, Ya-Bin L, Yang G, et al. Potential influence of COVID-19/ACE2 on the female reproductive system. Mol Hum Reprod. 2020;26(6):367-373.
  5. Seymen CM. COVID-19 pandemisinin kadın fertilitesi üzerine etkileri. Gazi Sağlık Bilimleri Dergisi. 2020; 5(3): 1-7.
  6. Yıldırım Baş F. Pandemide aşılamanın önemi ve COVİD 19 aşılama çalışmaları. SDÜ Tıp Fakültesi Dergisi. 2021; 28: 245-248.
  7. Li M, Wang H, Tian L, Pang Z, Yang Q, Huang T, et al. COVID-19 vaccine development: milestones, lessons and prospects. Signal Transduct Target Ther. 2022;7(1):146.
  8. Park JW, Lagniton PNP, Liu Y, Xu RH. mRNA vaccines for COVID-19: what, why and how. Int J Biol Sci. 2021;17(6):1446-1460.
  9. Wainstock T, Yoles I, Sergienko R, Sheiner E. Prenatal maternal COVID-19 vaccination and pregnancy outcomes. Vaccine. 2021;39(41):6037-6040.
  10. Gurol-Urganci I, Jardine JE, Carroll F, Draycott T, Dunn G, Fremeaux A, et al. Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection at the time of birth in England: national cohort study. Am J Obstet Gynecol. 2021;225(5):522.
  11. Hadar E, Dollinger S, Wiznitzer A. Coronavirus disease and vaccination during pregnancy and childbirth: a review of the Israeli perspective and experience. J Matern Fetal Neonatal Med. 2022;35(25):7794-7805.
  12. Trostle ME, Limaye MA, Avtushka V, Lighter JL, Penfield CA, Roman AS. COVID-19 vaccination in pregnancy: early experience from a single institution. Am J Obstet Gynecol MFM. 2021;3(6):100464.
  13. Arcangeli T, Thilaganathan B, Hooper R, Khan KS, Bhide A. Neurodevelopmental delay in small babies at term: a systematic review. Ultrasound Obstet Gynecol. 2012;40(3):267-275.
  14. Köksal N, Özkan H, Gider C, Kılıçbay İ, Kılıçbay F, Can S, et al. Gestasyon Haftasına Göre Düşük Doğum Ağırlığı SGA Olan Bebeklerin Uzun Süreli İzlemi. Güncel Pediatri. 2004; 2(2): 73-79.
  15. Gökçay G, Furman A, Neyzi O. Updated growth curves for Turkish children aged 15 days to 60 months. Child Care Health Dev. 2008;34(4):454-63.
  16. Fenton TR, Kim JH. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatr. 2013;13:59.
  17. Centers for disease control and prevention. COVID-19 Vaccines While Pregnant or Breastfeeding. [Internet]. 2022 [Updated Oct. 20, 2022; cited 2024 Jan]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/pregnancy.html
  18. Maternal – Fetal Tıp ve Perinatoloji Derneği [Internet]. Gebelerde ve Emziren Annelerde Covıd-19 Aşıları İle İlgili Türkiye Maternal Fetal Tıp Ve Perinatoloji Derneği Görüşü. 2021 [Updated Oct. 20, 2022; cited 2024 Jan]. Available from: https://www.tmftp.org/files/uzman-gorusleri/gebelerde_covid19_asisi.pdf.
  19. Lipkind HS, Vazquez-Benitez G, DeSilva M, Vesco KK, Ackerman-Banks C, Zhu J, et al. Receipt of COVID-19 Vaccine During Pregnancy and Preterm or Small-for-Gestational-Age at Birth - Eight Integrated Health Care Organizations, United States, December 15, 2020-July 22, 2021. MMWR Morb Mortal Wkly Rep. 2022;71(1):26-30.
  20. Ma Y, Shan Z, Gu Y, Huang Y. Safety and efficacy of inactivated COVID-19 vaccines in women vaccinated during the first trimester of pregnancy. Int J Infect Dis. 2023;130:196-202.
  21. Rahmati M, Yon DK, Lee SW, Butler L, Koyanagi A, Jacob L, et al. Effects of COVID-19 vaccination during pregnancy on SARS-CoV-2 infection and maternal and neonatal outcomes: A systematic review and meta-analysis. Rev Med Virol. 2023;33(3):e2434.
  22. Blakeway H, Prasad S, Kalafat E, Heath PT, Ladhani SN, Le Doare K, et al. COVID-19 vaccination during pregnancy: coverage and safety. Am J Obstet Gynecol. 2022;226(2):236.e1-236.e14