Journals / Journal of Experimental and Clinical Medicine / 2026 / Volume: 42 Issue: 1

Endovascular management of a persistent primitive trigeminal artery aneurysm initially misdiagnosed as pituitary adenoma: A case report

Anil Erol(EGE ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, BEYİN VE SİNİR CERRAHİSİ ANABİLİM DALI)0000-0002-6190-2732
Bilal Bahadır Akbulut(EGE ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, BEYİN VE SİNİR CERRAHİSİ ANABİLİM DALI)0000-0002-7983-5056
Celal Cinar(EGE ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, RADYOLOJİ ANABİLİM DALI)0000-0002-3237-9268
Mustafa Serdar Bölük(EGE ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, BEYİN VE SİNİR CERRAHİSİ ANABİLİM DALI)0000-0002-9406-4114
Taşkın Yurtseven(EGE ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, BEYİN VE SİNİR CERRAHİSİ ANABİLİM DALI)0000-0001-7982-8115
Hüseyin Biçeroğlu(EGE ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, BEYİN VE SİNİR CERRAHİSİ ANABİLİM DALI)0000-0003-2306-0826
Pages
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Publication Date
2025-03-28
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It also highlights the critical role of imaging techniques in identifying rare vascular anomalies.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Persistence of primitive intracranial embryonic anastomoses such as the permanent primitive trigeminal artery (PPTA) is rare, with the PPTA representing 80-85% of these cases.
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Key Findings & Data:We report a 64-year-old woman, initially evaluated for headache and dizziness, where cranial computed tomography (CT) incidentally suggested a hypodense sellar lesion.
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Conclusion & Impact:It also highlights the critical role of imaging techniques in identifying rare vascular anomalies.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:aneurysm · carotid-vertebrobasilar anastomoses · case report

Abstract

Persistence of primitive intracranial embryonic anastomoses such as the permanent primitive trigeminal artery (PPTA) is rare, with the PPTA representing 80-85% of these cases. Aneurysms associated with PPTA are rare. This presents diagnostic and therapeutic challenges. We report a 64-year-old woman, initially evaluated for headache and dizziness, where cranial computed tomography (CT) incidentally suggested a hypodense sellar lesion. Subsequently, on CT angiography, a 9 mm saccular aneurysm in the PPTA and an 18 mm aneurysm in the right internal carotid artery (ICA) cavernous segment were identified. Endovascular treatment with flow diverter stent implantation was successfully performed, followed by post-operative ticagrelor and acetylsalicylic acid therapy. The patient was discharged neurologically intact after three days of care in the hospital and there was no deterioration in neurological examination at 1-year follow-up. This case underscores the necessity of careful angiographic evaluation in patients with suspected pituitary masses to avoid potentially catastrophic misdiagnoses. It also highlights the critical role of imaging techniques in identifying rare vascular anomalies.

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Cite This Article

Erol, A., Akbulut, B. B., Cinar, C., Bölük, M. S., Yurtseven, T., Biçeroğlu, H. (2025). Endovascular management of a persistent primitive trigeminal artery aneurysm initially misdiagnosed as pituitary adenoma: A case report. Journal of Experimental and Clinical Medicine, Volume: 42 Issue: 1. https://ajindex.com/articles/1422618

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